Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eve  Namisango
ID: UNCST-2021-R014038
Piloting the use of sub-Saharan Africa spirituality guidelines and standards to support the integration of spirituality care into routine palliative care services at Kitovu Mobile hospice
REFNo: SS5371ES

2) To build a core team of palliative care and community health workers trained in generalist spiritual care ,1) To co-design a strategy for integrating spiritual care into routine palliative care services at Kitovu Mobile,To undertake a demonstration project on how to integrate spiritual care into routine palliative care leveraging evidence-based recommendations and standards alongside appropriate measures for assessment, management/support and measuring outcomes,
Uganda 2026-06-05 16:41:18 2029-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Development of Host Biomarker-Guided Approaches to Mitigate Endemic and Emerging Biothreats
REFNo: HS7512ES

To conduct comprehensive host transcriptomic and proteomic profiling of biospecimens previously collected under IRB approved protocols meeting clinical definitions of the syndromes Pneumonia, Acute Respiratory Distress Syndrome, Sepsis and Meningoencephalitis
Uganda 2026-06-05 16:30:22 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Local Validation and Calibration Assessment of the CerviCARE Artificial Intelligence Cervicography Tool Within Routine VIA-Based Cervical Cancer Screening in Uganda: A Mixed-Methods Study with Comparative Patient and Provider Experience Assessment
REFNo: HS7752ES

Primary objective: To compare the diagnostic performance of the CerviCARE AI tool with VIA performed by experienced screening midwives and healthcare workers within routine cervical cancer screening services at the Uganda Cancer Institute and its affiliated satellite site in Mbarara, and to characterise the tool’s agreement, calibration and operational performance within routine service delivery. Secondary objectives 1. To assess the quality-assurance performance of CerviCARE using colposcopy-directed biopsy and histopathological confirmation among a targeted subset of approximately 180 participants with abnormal, suspicious, borderline or discordant screening findings within the 1,500-woman validation cohort. 2. To assess and compare patient and healthcare provider experiences of routine VIA-based cervical cancer screening delivered with and without CerviCARE support, including understanding of results, communication, acceptability, trust, dignity, workflow, provider confidence and perceived usefulness within routine service delivery. 3. To quantify inter-observer variability in VIA interpretation among study providers and to assess how CerviCARE outputs align with consensus VIA and histology in discordant cases.
Uganda 2026-06-05 16:26:45 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
Efficacy of a High-Calorie High-Protein Supplement on Weight for Age and Mid Upper Arm Circumference of Children with Special Needs in Uganda
REFNo: HS7734ES

Assess caregiver knowledge, attitudes and practices regarding the preparation, use and perceived benefits of the supplement,Assess the effect of the supplement on weight for age and mid upper arm circumference among children with CP,To analyze the nutrient composition of the 1-week pureed food menu provided at the orphanage using the MyDietAnalysis program to determine its adequacy in meeting the nutritional requirements of the children.,Develop an energy-protein dense supplement to improve nutritional status of children with Celebral Palsy and other disabilities.,To test the efficacy of a sustainable high-calorie, high-protein supplement in therapeutic care of malnourished Ugandan children with disabilities. ,
Uganda 2026-06-05 16:24:12 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Max Bobholz
ID: UNCST-2025-R021763
Health-related quality of life and environmental distress among climate-displaced communities in Uganda
REFNo: HS7560ES

4.1. General Objective
The general objective of this study is to characterize, summarize, and explore the connection between CRD and the current health-related QoL and environmental distress circumstances of CRMs in Uganda, focusing on both the national level and within a single IDP camp.


4.2. Specific Objectives
We propose two specific objectives that run in parallel to one another.
Objective 1: Characterize key stakeholders’ understanding of the causes and health-related consequences of CRD in Uganda. This objective will investigate stakeholders’ understanding of CRM circumstances in Uganda, particularly the types of climate factors contributing to displacement, the challenges faced by this population, and potential strategies for improving their health, using key informant interviews.
Objective 2: Explore how climate-related displacement experiences, aspects of vulnerability, and resilience contribute to quality of life and environmental distress (e.g., solastalgia and loss of place) throughout migration journeys of climate-related migrants in the Muhokya IDP Camp in Kasese District. Guided by an emerging method that blends geospatial mapping and narrative analysis,20 we will qualitatively explore the displacement, QoL, and distress experiences of CRMs.

USA 2026-06-05 16:22:02 2029-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Kembabazi Juliet
ID: UNCST-2025-R017646
EMPLOYEE PERCEPTIONS OF ATTRACTION AND RETENTION IN PRIVATE UNIVERSITIES IN UGANDA. A CASE OF PRIVATE CHARTERED UNIVERSITIES IN WESTERN UGANDA
REFNo: SS5050ES

THE STUDY AIMS AT EXAMINING HOW EMPLOYEE PERCEPTIONS INFLUENCE ATTRACTION AND RETENTION OF EMPLOYEES IN PRIVATE UNIVERSITIES IN WESTERN UGANDA
Uganda 2026-06-05 16:19:37 2029-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
NSUBUGA GERALD
ID: UNCST-2021-R011633
Feasibility and Acceptability Using Umbilical Cord Blood for Cancer Treatment through Stem Cell Transplantation: A Multi-Center Study Involving Pregnant Mothers, Health Workers, and Cancer Patients in Collaboration with the Uganda Blood Transfusion Service
REFNo: HS6131ES

General Objective To assess the feasibility and acceptability of collecting and using umbilical cord blood for stem cell transplantation in cancer patients based on the perceptions and readiness of pregnant mothers, health professionals, and cancer patients in selected public health facilities in Uganda. Specific Objectives 1. To determine the level of awareness and knowledge about umbilical cord blood stem cell transplantation among pregnant mothers, health professionals, and cancer patients. 2. To assess the willingness of pregnant mothers to donate umbilical cord blood for therapeutic use. 3. To evaluate the preparedness of health professionals to support UCB collection, processing, and utilization.
Uganda 2026-06-05 15:35:56 2029-06-05 Medical and Health Sciences Clinical Trial Non-degree Award
Begumisa Godfrey Magyezi
ID: UNCST-2024-R002711
Remediation of Schistosome cercaria and fecal bacteria from contaminated water sources using a constructed wetland and Electrochlorination
REFNo: NS1253ES

3. To determine the enhancement potential of the sequential vertical flow CW and EC in treatment of water contaminated with schistosome cercariae and fecal indicator bacteria,2. To determine the best practices of a vertical flow constructed wetland for schistosome cercariae and fecal contamination indicator bacteria removal,1. To establish the best practices of EC application for schistosome cercaria and fecal indicator bacteria disinfection ,To investigate the best practices for schistosome cercariae and fecal bacteria remediation from polluted water sources of the schistosomiasis hot spot region of Lake Albert, western Uganda,
Uganda 2026-06-01 18:19:31 2029-06-01 Natural Sciences Degree Award
Drake Musoki
ID: UNCST-2026-R023417
Assessing Usability and Patient preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV in Uganda.
REFNo: HS7482ES

General Objective To Assess the Usability and Patient Preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV attending Mildmay Hospital, Uganda. Specific Objectives 1. To assess Usability of the Luganda SRQ-20 by evaluating the comprehension, ease of use and completion time among PLHIV. 2. To explore patient preferences by identifying the desired mode of delivery mode (self vs health-worker administered). 3. To determine the perceived barriers and necessary adaptations to make the SRQ-20 accessible to diverse PLHIV populations (i.e. with disabilities, low literacy levels, urban vs rural).
Uganda 2026-06-01 18:18:14 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Okeny
ID: UNCST-2021-R012931
The PARSNIP Study PREVALENCE AND FACTORS ASSOCIATED WITH LOW ANTERIOR RESECTION SYNDROME AND QUALITY OF LIFE AMONG PATIENTS UNDERGOING SURGERY FOR RECTAL CANCER IN UGANDA.
REFNo: HS7451ES

Aim 1
To determine the prevalence and factors associated with low anterior resection syndrome (LARS) among patients undergoing low anterior resection for rectal cancer in Uganda.
Specific Objectives
1. To determine the prevalence of Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
2. To describe factors associated with Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
Aim 2
To evaluate the health-related quality of life and factors associated with a poor quality of life among patients who have had surgical resection for rectal cancer in Uganda.
Specific objectives
1. To determine the quality of life of patients who have had surgical resection for rectal cancer in Mulago Hospital.
2. To assess the factors associated with a poor quality of life following surgical resection for rectal cancer in Mulago Hospital.

Uganda 2026-06-01 18:15:40 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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