Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
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ESTIMATION AND EXPLANATIONS FOR THE HYPERTENSION SCREENING GAP AMONG HIV-INFECTED PATIENTS IN HIV PRIMARY CARE.
REFNo: HS118ES
1. Estimate the screening gap for hypertension among HIV-infected adults on ART attending Uganda Cares HIV primary care clinics in Masaka, Rakai and the St. Balikudembe Clinic in Kampala, Uganda over 12 months.
2. Document explanations for the screening gap for hypertension from the perspective of health providers at the Uganda Cares HIV primary care clinic in Masaka, Rakai and St. Balikudembe Clinic in Kampala, Uganda.
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Uganda |
2017-11-28 |
2020-11-28 |
Medical and Health Sciences |
|
Non-degree Award |
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Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
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EVALUATION OF THE USE OF TELEDERMATOLOGY AMONG PRIMARY CARE PATIENTS IN KAMPALA
REFNo: HS3655ES
Aim 3: Define the distribution of dermatologic diagnoses that arise in primary care settings in which TD is used and their subsequent management. ,Aim 2: Evaluate the barriers and facilitators to implementation of the TD service,Aim 1: Describe the utilization of TD in ambulatory care settings. ,
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Uganda |
2024-02-02 11:24:53 |
2027-02-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
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Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS)
REFNo: HS5498ES
•Aim 1: Refine SkinScan3D Technology and Usage Protocols for Routine KS Imaging:
•Aim 2: Compare Reproducibility and Accuracy of KS Lesion Size Measurements Between SkinScan3D and Current Standard of Care Measurement.
•Aim 3: Validate and Optimize SkinScan3D Clinical Workflow in Real-World Settings.
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Uganda |
2025-04-11 16:47:49 |
2028-04-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Sarah Lofgren
ID: UNCST-2019-R001647
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The Growth Study- Group Therapy In HIV For Depression In Uganda
REFNo: HS493ES
Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
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USA |
2019-12-09 |
2022-12-09 |
Medical and Health Sciences |
|
Non-degree Award |
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Sarah Lofgren
ID: UNCST-2019-R001647
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Supervised Treadmill intervention to Reduce Inflammation and Depression through Exercise in HIV: The STRIDE Pilot Study
REFNo: HS3358ES
The objective of this study is to determine the feasibility and acceptability of an aerobic intervention via a treadmill among individuals with HIV and depression in Uganda.
3.1 Primary Endpoint: Feasibility and acceptability of Exercise as a treatment for depression in Ugandans with HIV. This will be measured by:
-Percent completion of the prescribed aerobic exercise intervention, as assessed by research staff logging participation.
3.2 Secondary Endpoint(s)/ Outcome(s):
- acceptability of the intervention assessed via a post intervention survey
-feasibility and acceptability of using a wearable exercise tracker to assess the volume of exercise, based on calories burned and steps achieved, during the intervention period among Ugandans with HIV and depression.
- measure the mean and standard deviation of baseline and 8-week serum BDNF and IL-6 level to estimate an effect size and power a future study.
- measure the mean and standard deviation of baseline and 8-week depression score via PHQ-9 to estimate an effect size and power a future study.
- measure the mean and standard deviation in aerobic fitness baseline and at 8 weeks measured via METS/watts achieved and total time/distance to estimate the effect size for a future intervention.
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USA |
2024-02-26 13:41:23 |
2027-02-26 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Robert Buwule Stalone
ID:
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Re-Engineering Research and Innovation Information in University Libraries in Uganda for Small and Medium Enterprises (SMEs) in the Agricultural Sector
REFNo: IS6ES
a) To investigate how University libraries in Uganda are facilitating access to Research and Innovation information for use by Small and Medium Enterprises in the agricultural sector in Uganda.\r\nb) To find out the extent to which University libraries in Uganda repackage Research and Innovation information for use by Small and Medium Enterprises in the agricultural sector in Uganda.
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Uganda |
2017-02-24 |
2020-02-24 |
Social Science and Humanities |
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Degree Award |
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Robert Buwule Stalone
ID:
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Use of COVID-19 surveillance applications in Uganda
REFNo: SS1477ES
To design a health-based ICT COVID-19 surveillance framework for community health,To establish the drivers and barriers of adopting health-based ICT surveillance applications in Uganda,To examine the adoption and integration of the surveillance applications in the community health practices in Uganda,To assess the efficacy of the existing health-based ICT surveillance applications in the communities in Uganda,To identify health-based ICT surveillance applications developed to mitigate the COVID-19 pandemic in Uganda,To establish the level of application of Covid-19 Surveillance applications ICT innovations in community health during the COVID-19 pandemic in Uganda with a view of suggesting a health-based ICT framework for community health,
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Uganda |
2022-11-29 12:33:19 |
2025-11-29 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Megan Swanson
ID:
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Identifying Barriers and Facilitators to Cervical Cancer Care in Kampala, Uganda
REFNo: HS29ES
The overall goal of this project is to identify the barriers to cervical cancer care in Kampala, Uganda. Specific aims are as follows:\r\n\r\nAim 1: Describe the prevalence of cervical cancer by stage and factors associated with late versus early-stage diagnoses.\r\n\r\nAim 2: Describe the intervals of time in the process of obtaining care for cervical cancer.\r\n\r\nAim 3: Describe the challenges doctors at referral hospitals face in providing cervical cancer care.\r\n
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USA |
2017-02-21 |
2020-02-21 |
Medical and Health Sciences |
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Non-degree Award |
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ALEX KAYONGO
ID: UNCST-2019-R001641
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In-vitro Susceptibility of Broncho-alveolar-derived Macrophages to Mycobacterium tuberculosis among persistently IGRA-negative TB household contacts in Uganda
REFNo: HS1767ES
Study Aim:
Phenotypic characterization of persistently IGRA-negative individuals based on in-vitro killing of luciferase-expressing recombinant Mtb in broncho-alveolar lavage.
Specific Objectives
1. To demonstrate in-vitro BAL and blood monocyte derived macrophage killing of luciferase-expressing recombinant Mtb among persistently IGRA-negative individuals.
2. To validate in-vitro BAL-derived macrophage killing assays using virulent Mtb strains identified from “the Ugandan TB cohort.
3. To compare BAL-derived macrophage expression profiles for selected cytokines, phagocytic receptors, phagosome maturation and microbial killing genes between IGRA-negative and positive individuals.
4. To compare levels of selected macrophage cytokines and chemokines in BAL supernatant between IGRA-negative and positive individuals.
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Uganda |
2022-03-03 |
2025-03-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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ALEX KAYONGO
ID: UNCST-2019-R001641
|
Airway Microbiome and Th17-mediated inflammation in COPD among HIV-infected individuals in a rural Ugandan cohort
ACRONYM: HIV-LUNG MICROBIOME (HLM) study
REFNo: HS2035ES
Study aim:
To investigate airway microbiome-driven Th17 mediated inflammation in COPD among HIV-infected individuals
Specific objectives
1. To establish a relationship between airway microbiome and Th17/Treg cellular phenotypes among HIV-infected individuals with COPD.
2. To investigate bacterial mediated Th17 up-regulation of pro-inflammatory genes among HIV-infected individuals with COPD.
3. To investigate the role of bacterial outer membrane vesicles (OMVs) in mediating dysbiosis driven Th17 immune responses among HIV individuals.
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Uganda |
2022-02-10 |
2025-02-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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ALEX KAYONGO
ID: UNCST-2019-R001641
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Mechanisms of Immune Resistance to Mycobacterium tuberculosis
REFNo: HS3165ES
Aims: In this study, we will immuno-phenotype airway microbiome signatures as innate, Th1, Th2, Th17, or Treg-inducing using a chronic airway inflammation population. We will then determine the association between airway microbiome, M.tb-specific IFN-gamma responses, and M.tb burden based on GeneXpert status to underpin immune protective microbial signatures. Finally, we will validate identified immune-protective microbial signatures as a proxy for IFN-gamma reactivity and TB immune protection in a separate cohort of persistently QFT-negative individuals compared to household LTBI controls.
|
Uganda |
2023-10-13 11:01:43 |
2026-10-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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ALEX KAYONGO
ID: UNCST-2019-R001641
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Clonotyping Airway T-cells to Uncover Microbiome-Specific Inflammotypes in HIV-Associated COPD
REFNo: HS6625ES
Study Aim:
To investigate the airway microbiome-specific inflammotypes in COPD among HIV-infected individuals in a rural Uganda.
Specific objectives
1.To determine, in vitro, the CD4+T-cell clonotypic library specific to airway bacterial species associated with COPD among HIV-infected individuals in rural Uganda.
2.To determine, ex vivo, the microbiome-specific clonotypic landscape of BAL-derived CD4+T cells from a cohort of individuals stratified by HIV and COPD in rural Uganda.
3.To validate airway microbiome-specific inflammotypes among individuals with COPD transitioning from stable disease to exacerbation and back to stable disease.
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Uganda |
2025-10-29 12:47:04 |
2028-10-29 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Imelda Namagembe
ID:
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ETHICAL CHALLENGES ENCOUNTERED BY RESEARCHERS AND INSTITUTIONAL REVIEW BOARD MEMBERS IN EMERGENCY OBSTETRICS –GYNAECOLOGY CARE RESEARCH: A CASE STUDY OF MAKERERE COLLEGE OF HEALTH SCIENCES/MULAGO HOSPITAL, UGANDA.
REFNo: HS31ES
General Objective:\r\nTo explore and document ethical challenges encountered in emergency obstetrics-gyneacology research by researchers and IRB members at Makerere College of Health Sciences/Mulago Hospital, Uganda".\r\nSpecific objectives\r\n1) To explore the ethical challenges encountered in emergency obstetrics-gynaecology research by researchers at Makerere College of Health Sciences and Mulago Hospital.\r\n2) To explore the ethical and operational challenges encountered by IRB members when reviewing / monitoring research in emergency obstetrics-gynecology. \r\n3) To document the strategies used by both researchers and IRB members to handle the ethical and operational challenges encountered in emergency obstetrics-gynecology research\r\n
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Uganda |
2017-01-31 |
2020-01-31 |
Medical and Health Sciences |
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Non-degree Award |
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Phoebe Donnelly
ID:
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Gendered Decisions and Dynamics in Eastern Africa
REFNo: SS109ES
This research is for my PhD dissertation and potentially a book or articles. My central research question asks how the attitudes and behavior of non-state armed organizations (NSAOs) towards women and girls relate to the NSAO’s broad strategy. My framework will examine four aspects of gendered strategy: 1) the role women and girls fill within NSAOs; 2) whether NSAOs use forced marriage or other regulations of relationships as a strategy; 3) how the treatment of civilian women and girls, specifically the use of gender-based violence (GBV), relates to the objectives of the NSAO; and 4) how these organizations discuss gender in their external communications. My two case studies are al-Shabaab formed in Somalia and the Lord's Resistance Army in Uganda.
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USA |
2017-12-20 |
2020-12-20 |
Social Science and Humanities |
|
Degree Award |
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Fred Bulamba
ID: UNCST-2019-R000026
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Non-Physician Anaesthetists’ training and roles in sub-Saharan Africa
REFNo: HS30ES
This study aims to 1) characterise the training programmes currently available for NPAs in sub-Saharan Africa (SSA), with respect to their structure, curricula and teaching methods, 2) characterise the output of NPA training programmes in terms of NPA roles and the proportion of total anaesthesia providers who are NPAs, and 3) explore the experience of key informants in selected locations with regard to NPA training and practice.\r\n
|
Uganda |
2017-04-25 |
2020-04-25 |
Medical and Health Sciences |
|
Non-degree Award |
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Fred Bulamba
ID: UNCST-2019-R000026
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Mapping perioperative care pathways to support surgical treatment in Low-and-Middle Income Countries
REFNo: HS642ES
The aim of this project is to understand the context of perioperative health systems in Uganda, including the main barriers encountered in the delivery of care.
Objectives:
1. Develop a collaborative approach to perioperative care pathway mapping
2. Carry out a rapid appraisal to map 5 pathways (three “Bellwether procedures and two elective procedures) in Uganda.
3. Refine the process and extend to three low- and middle-income countries
|
Uganda |
2020-09-28 |
2023-09-28 |
Medical and Health Sciences |
|
Non-degree Award |
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Ulrich Kropiunigg
ID:
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Understanding the Preventative and Protective Potential of Fathers: Safeguarding Children from Extremist Influences
REFNo: SS50ES
1.Gain a deeper understanding of extremist mechanisms at the individual psychological/ emotional\r\nlevel from the perspective of fathers.\r\n2.Investigate how fathers can be employed in shielding their children from extremist influences.\r\n3.Develop an understanding of the skills that fathers require in order to effectively prevent and protect\r\ntheir children from extremist influences.
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Austria |
2017-02-21 |
2020-02-21 |
Social Science and Humanities |
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Non-degree Award |
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Xavier Medialdea Pedrol
ID:
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Livestock diet quality and overgrazing in Queen Elizabeth National Park
REFNo: NS7ES
Understanding determinants of livestock movement on spatial and temporal dimensions and link it to the use of resources in an outside Queen Elizabeth National Park while the nutritional and healthy status of the animals is studied. This can be achieved by monitoring the diet quality and parasites of livestock and the forage availability through space and time in and near the northern part of Queen Elizabeth National Park.
|
Spain |
2017-02-28 |
2020-02-28 |
Natural Sciences |
|
Non-degree Award |
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Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
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Engaging Young People in the Development of Digital Mental Health Innovation in Africa
REFNo: SS795ES
To build a network of experts and stakeholders to develop a framework for responsible and relevant digital mental health interventions for young people in African countries
|
Uganda |
2021-05-10 |
2024-05-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
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DESIGN AND FABRICATION OF A LUMBAR MODIFIED SPINAL BRACE
REFNo: HS1558ES
Our main objective is to design, fabricate and test a modified fit-for-purpose lumbar orthosis through use of locally available raw materials whose design can be adopted by different orthopaedic workshops in low income countries. This will be achieved through the following sub aims;
1. Conduct a needs assessment to determine the needs and requirements of people with low back pain and derive specifications for a modified brace well suited for use by people in LICs.
2. Test and assess the functionality of the modified brace using simulations.
3. Fabricate a sturdy brace with locally sourced components that suits the specifications derived from the simulations so as to make it suitable for use in low income countries.
|
Uganda |
2021-07-30 |
2024-07-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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