Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Dickens Akena Howard
ID: UNCST-2019-R000179
Developing a peer support model for depression care in patients with diabetes mellitus, and testing it’s efficacy on patient outcomes; a randomized control trial.
REFNo: HS20ES

The main study objective will be developing a peer support model of depression care for patients with DM and testing its efficacy on clinical outcomes
Uganda 2017-02-24 2020-02-24 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
The effect of psycho-education on clinical outcomes among patients with a first episode psychosis in central Uganda - A pilot randomized control trial
REFNo: HS1026ES

The study objectives are to (a) Conduct formative work and develop a manual for delivering psycho-education messages by Village Health Team (VHTs) members to individuals with first episode psychosis (FEP) and their families in central Uganda. (b) Examine the efficacy of psycho-education on symptom severity, stigma and retention in care. (c) Document feasibility and acceptability of implementing this intervention as well as barriers to its implementation
Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Integration of mental health care in communities affected by the COVID-19 pandemic - A cluster randomized trial of 24 villages in central Uganda
REFNo: HS1009ES

Our objectives will include: (a) Documenting MHL, PD, MDD, GAD, PTSD and SUD levels in the study population, (b) Determining the effectiveness of a psycho-education intervention delivered by village health team (VHT) members on study outcomes, (c) Determining the cost and cost effectiveness of delivering a psycho-education intervention, and (d) linking individuals in need of mental health care with the MOH psychosocial teams.
Uganda 2020-12-15 2023-12-15 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Genetics of Post-Traumatic Stress Disorders (PTSD) in African Ancestry Populations
REFNo: HS3156ES

(i) Expand knowledge of the genetic architecture of PTSD in the African continent through large-scale sample collection and analysis, (ii) Increase understanding of the high burden of trauma and PTSD faced by African populations and (iii) Enhance neuropsychiatric genetic research capacity in Uganda through the training of scientists and support the development of locally led research programs


Uganda 2023-09-19 8:11:56 2026-09-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
NeuroGAP follow up study on Anhedonia, OCD, Discrimination, and Suicidality
REFNo: HS3158ES

1.Characterize anhedonia, OCD, stigma, and suicidality using diagnoses and item-level data collected across the NeuroGAP samples. 2. Generate high-quality harmonized phenotype data across psychiatric conditions in the study population, and 3. Conduct genetic analyses aimed at identifying genes linked to anhedonia, OCD, stigma and suicidality in the NeuroGAP-Psychosis the Ugandan populations, develop population-valid polygenic risk scores and contribute data to global meta-analyses aimed at identifying genes for these psychiatric conditions in African and trans-ethnic populations.
Uganda 2023-09-08 14:00:44 2026-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Cultural adaptation of the coordinated specialty care (NAVIGATE) in Uganda
REFNo: HS6280ES

Study objective: The study objectives will include

Objective 1. Culturally adapting and locally contextualizing NAVIGATE into a CSC manual (NAVIGATE-UG) for use in Uganda.

Objective 2: Documenting the feasibility and acceptability of using the adapted NAVIGATE-UG manual

Uganda 2025-08-18 13:24:11 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Neuropsychiatric Genetics of African Populations - Psychosis, II NeuroGAP-Psychosis II
REFNo: HS6452ES

i). Expand knowledge of the genetic architecture of schizophrenia and bipolar disorder in the African continent
through large-scale sample collection and analysis in Uganda
ii) Increase understanding of the genetics of African populations, through various methods for biospecimen
collection
iii) Enhance neuropsychiatric genetic research capacity in Africa through the training of scientists and supporting
the development of locally-led research programs
Uganda 2025-08-27 14:38:09 2028-08-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOHN FAITH MAGOLO FAITH
ID:
APPROPRIATENESS OF EARLY WARNING SYSTEMS IN THE MANAGEMENT OF CLIMATE CHANGE IMPACTS IN MT. ELGON REGION IN EASTERN UGANDA
REFNo: SS13ES

1. To find out the level of risk Knowledge in the management of the impacts of Climate change in the Mt. Elgon region in Eastern Uganda. \r\n2. To establish the level of technical monitoring in the management of the impacts of climate change in the Mt. Elgon region in Eastern Uganda. \r\n3. To investigate the appropriateness of communication on the management of the impacts of climate change in the Mt. Elgon region in Eastern Uganda.\r\n4. To establish the appropriateness of response capability on the management of the impacts of climate change in the Mt. Elgon region in Eastern Uganda. \r\n
Uganda 2016-12-21 2019-12-21 Social Science and Humanities Degree Award
Christopher Tumwine
ID:
A QUALITATIVE STUDY OF THE AGRICULTURAL LIVELIHOOD SUPPORT PROGRAMME TO PERSONS LIVING WITH HIV IN UGANDA
REFNo: HS1954ES

To assess whether HIV programmes in Uganda still need to provide livelihoods’ support to persons living with HIV in the era-of test and treat. To examine clients’ perspectives on changes/benefits experienced as a result of participating in the agricultural livelihood support programme. To examine challenges which have been experienced by clients as result of participating in the agricultural livelihood support programme. To examine key stakeholders’ perspectives on the process, benefits and challenges of the agricultural livelihood support programme to HIV clients.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jesca Audo Harriet
ID: UNCST-2019-R000209
STUDENT LEARNING ACTIVITIES IN BIOLOGY LESSONS AS MEDIATORS OF SELF-EFFICACY AND GENERIC SKILLS IN UGANDA’S NEW LOWER SECONDARY CURRICULUM
REFNo: SS3915ES

The following objectives will serve as the study's direction. 1.To determine the level of student learning activities designed for students during Biology lessons in the lower secondary schools. 2.To determine the level of acquisition of generic skills among students during Biology lessons in the lower secondary schools. 3.To investigate the relationship between self-efficacy and student learning activities during Biology lessons in the lower secondary schools. 4.To examine the relationship between self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary school. 5.To examine the relationship between student learning activities and generic skills acquisition among students during Biology lessons in in the lower secondary schools. To investigate the mediating effect of student learning activities in relation to self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary schools.
Uganda 2025-06-20 7:34:34 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Peter Schüle
ID:
World-wide phylogeny and biodiversity of beetle associated nematodes and faunistic data of different groups of insects: Carabidae, Cicindelidae, Scarabaeidae and Odonata
REFNo: NS5ES

 Increasing the knowledge of the inventory of the Cicindelidae species of Uganda\r\n Obtaining better knowledge about biogeographic patterns about Carabidae and other beetle groups in Uganda\r\n include the data of Central African Nematodes into the world-wide research project on the biogeography of Nematodes\r\n
Germany 2016-11-07 2019-11-07 Natural Sciences Non-degree Award
Robert Kalyesubula
ID:
Task Shifting Screening and Measurement of Blood Pressure and Blood Sugars by Community Health Workers for Early Detection and Referral of Hypertension and Diabetes in Rural Uganda.
REFNo: SS821ES

1. To train CHWs in detection, referral, and promotion of continuity for diabetes and
hypertension care among community members in Nakaseke district, Uganda.
2. To assess the ability of trained CHWs to detect and refer patients with diabetes and or hypertension in Nakaseke district.
3. To determine compliance to diabetes and hypertension referral care among community
members in Nakaseke district
Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Effectiveness of a community health worker delivered care intervention for hypertension control in Uganda: a stepped wedge, cluster randomized control trial.
REFNo: HS1917ES

To assess the effectiveness of a CHW-delivered intervention for hypertension control in Uganda.,
Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Human-centered design to adapt and inform an integrated chronic disease management program in Uganda using mobile payment services. (Acronym: IMPEDE CVD)
REFNo: HS2445ES

1)To understand patient and provider perspectives on the potential and acceptability of financing schemes and mHealth interventions aimed at strengthening behavior in relation to ideal drug availability and uptake among NCD patients (Work Package (WP) 1a).
2)To develop together with end-users a prototype for a mobile phone-based solution (including mobile-based nudges) to increase the availability and uptake of NCD drugs (WPs 1b, and 2).
3)To test the prototype, establishing proof of concept, and to assess end-users’ experiences interacting with two versions of the prototype (comparing two saving models), including how users make and evaluate payment management decisions, in preparation for a subsequent study (WP 3).
Uganda 2022-10-20 18:01:35 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Sara Cavallo
ID:
Linking Banana Xanthomonas wilt and agro-ecological intensification to food practices in Kabarole District, Uganda
REFNo: SS37ES

This research seeks to understand the knowledge networks that have formed in light of Banana Xanthomonas Wilt and how knowledge is translated from scientists to extension to farmers and how knowledge flows influence landscapes.
USA 2016-12-06 2019-12-06 Social Science and Humanities Degree Award
Grace Ryan Kathryn
ID:
MIND ME Uganda: using Mental health INformation anD Monitoring and Evaluation systems to evaluate recovery-oriented mental health services in Kampala and Entebbe, Uganda
REFNo: HS12ES

The aim of this research is to carry out a mixed-methods evaluation of the Brain Gain II project and its mental health information and monitoring and evaluation (MIND ME) system, in order to inform policy regarding the continuation and scale-up of recovery-oriented mental health interventions in Uganda.\r\n\r\nObjectives include:\r\n\r\n1.To evaluate Brain Gain II’s MIND ME system, using mixed-methods to assess eight key implementation outcomes, including: acceptability, adoption, appropriateness, cost, coverage, feasibility, fidelity, sustainability\r\n\r\n2.To generate evidence on the effectiveness of Brain Gain II interventions using MIND ME\r\n\r\n3.To evaluate the general process and impact of implementing the Brain Gain II programme, by triangulating evidence generated through MIND ME with evidence generated through original research\r\n
USA 2016-12-06 2019-12-06 Medical and Health Sciences Degree Award
Twaha Rwegyema
ID:
Assessment of Dietary Patterns for People Living with HIV seeking health services from Regional Referral Hospitals in Uganda
REFNo: HS13ES

1. To identify the foods commonly consumed by PLHIV attending HIV clinics at RRH in Uganda.\r\n2. To compare dietary patterns of malnourished and non-malnourished HIV patients attending HIV clinics at RRH in Uganda.\r\n3. To explore demographic, socio-economic and hospital care factors associated with dietary patterns among HIV patients attending HIV clinics at RRH in Uganda.\r\n4. To identify and compare coping mechanisms during food scarcity between the malnourished and non-malnourished HIV patients attending HIV clinics at RRH in Uganda.
Uganda 2016-11-23 2019-11-23 Medical and Health Sciences Non-degree Award
Harriet Birabwa-Oketcho
ID:
SERVICE QUALITY AND PATIENT SATISFACTION WITH HEALTH SERVICES AT BUTABIKA HOSPITAL
REFNo: HS2275ES

General objective
The general objective of the study is to examine the relationship between service quality and patient satisfaction with health services at Butabika Hospital.




Specific Objectives
1. To determine the level of service quality of health services at Butabika Hospital.
2. To determine the level of patient satisfaction with health services at Butabika Hospital.
3. To determine the relationship between the service quality and patient satisfaction with health services at Butabika Hospital.
4. To assess the relationship between the patient related factors and patient satisfaction with health services at Butabika Hospital.

Uganda 2022-07-20 17:46:10 2025-07-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Birabwa-Oketcho
ID:
FORMAL AND ALTERNATIVE CARE SERVICES FOR SEVERE MENTAL ILLNESS: AN EXPLORATIVE PHASED MIXED METHODS STUDY MAPPING PATTERNS AND PERSPECTIVES ON USE AND COLLABORATION
REFNo: HS3616ES

1. To determine the patterns of use of AHCPs among patients with severe mental illness.
2. To determine factors associated with use of AHCPs among patients with severe mental illness.
3. To explore perspectives of persons with severe mental illness and their caregivers regarding use of AHCPs and formal healthcare.
4. To explore perspectives of health care personneland AHCPs regardinguse offormal service providers and the AHCPs.
5. To explore perspectives of health care personnel and AHCPs regarding collaboration between formal service providers and the AHCPs.
Uganda 2024-03-14 18:34:15 2027-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Kiene Maria
ID:
Use, Acceptability and Feasibility of a Pilot mHealth Intervention in Control of Diarrhoea in Kayunga District Uganda
REFNo: HS16ES

The proposed project will assess the use, acceptability and feasibility of a mHealth (mobile-phone technology for health) intervention that uses mHealth to help caregivers in rural Uganda establish tailored information on appropriate at-home care for diarrhoea or referrals for treatment based on the patient/child’s symptoms. \r\n\r\nThe specific objectives are:\r\n1. Obtain community feedback on the preliminary version of the mHealth intervention to refine the intervention, the app—user interactions, and procedures for promoting the intervention in the community.\r\n2. Make the intervention to one community of approximately 3,000 residents for 3 months and evaluate: use, acceptability, and feasibility of the intervention. \r\n3. Based on the findings, revise the mHealth intervention for testing in a larger trial to assess its effectiveness in reducing the time to treatment, cases of severe diarrhoea, and mortality. \r\n
USA 2016-10-18 2019-10-18 Medical and Health Sciences
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