Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Norma Ojehomon
ID: UNCST-2025-R022318
 Navigating Global Health Governance: The Social Life of Data, Sustainability, Local Ownership, and Governance Amid the Realignment of U.S. Aid and USAID
REFNo: SS4720ES

The study aims to examine how recent shifts in U.S. foreign assistance and global health governance are being interpreted, negotiated, and experienced by practitioners, policymakers, and stakeholders, with a focus on implications for sustainability, local ownership, and data governance. Specifically, the study seeks to:

1. Document practitioner perspectives on the dissolution of USAID and the reconfiguration of global health governance structures.


2. Examine how notions of sustainability and local ownership are being articulated and operationalized during this transition.


3. Explore the role of data, evidence, and reporting systems in shaping decision-making and power relations in the post-USAID landscape.

 USA 2026-02-10 16:04:18 2029-02-10 Social Science and Humanities Non-Clinical Trial Degree Award
Zoe Turner Jayne
ID: UNCST-2025-R022328
 The evolution of collective conflict in banded mongooses
REFNo: NS1127ES

Examine the evolution of conflict in a cooperative breeding mongoose (Mungos mungo), through a thorough exploration of temporal scales and individual roles prior to, during, and consequence to conflict.

Develop the use of a novel UAS imaging method integrated with ATLAS remote live tracking technology to widen the understanding of conflict in cooperative and cohesive animal species beyond what is typically observable.
 UK 2026-02-10 16:07:23 2029-02-10 Natural Sciences Non-Clinical Trial Degree Award
Susan Lamunu Shereni
ID: UNCST-2025-R022324
 Assessment and development of infectious diseases institute environment, social, and governance strategy, policy, and net zero roadmap
REFNo: SS5056ES

To assess and develop a comprehensive sustainability framework for the Infectious Diseases Institute (IDI) that strengthens institutional resilience, compliance, and accountability in alignment with local and international standards.1. To identify sustainability risks, gaps, opportunities, and strengths relative to Ugandan legal requirements, funder expectations, and international standards (e.g., GRI, IFRS, SDGs). 2. To map and engage key internal and external stakeholders to understand sustainability priorities, perceptions, and expectations of IDI’s sustainability performance. 3. To evaluate IDI’s environmental impact, including greenhouse gas (GHG) emissions, waste management, and resource utilisation. 4. To develop an institutional sustainability strategy, policy, and implementation roadmap. 5. To develop a Net Zero plan and monitoring and evaluation (M&E) matrix. 6. To develop an Environmental Aspects and Impacts Register to guide ongoing environmental management and compliance.
 Uganda 2026-04-10 19:10:56 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nalwanga Lillian Edith
ID: UNCST-2025-R022342
 HYPOXIC ISCHAEMIC ENCEPHALOPATHY CASEFATALITY, AND ITS ASSOCIATED FACTORS AMONG NEONATES AT KAYUNGA REGIONAL REFERRAL HOSPITAL
REFNo: HS7419ES

Main Objective 1. To determine the case fatality rate and its associated factors among neonates diagnosed with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital. Specific Objectives 1. To determine the case fatality rate among neonates diagnosed with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital between 1st January 2022 to 31st December 2025. 2. To identify maternal and intrapartum factors associated with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital. 3. To identify neonatal factors associated with the hypoxic-ischaemic encephalopathy case fatality rate at Kayunga Regional Referral Hospital.
 Uganda 2026-04-27 11:40:12 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Tom Joseph Mukasa
ID: UNCST-2025-R022357
 INTEGRATING LIFECYCLE SUSTAINABILITY ASSESSMENT METRICS INTO COST MANAGEMENT PRACTICES: A MODEL-BASED APPROACH FOR UGANDA\'S PUBLIC SECTOR CONSTRUCTION PROJECTS
REFNo: SIR645ES

This research aims to develop a model for integrating Lifecycle Sustainability Assessment (LCSA) metrics into cost management practices within Uganda's public sector construction projects. This model seeks to enhance cost accuracy, improve transparency, and achieve better sustainability outcomes. To achieve the general objective, the research will focus on the following specific objectives: 1. Analyse the current cost management practices in Uganda’s public sector construction projects. 2. Evaluate the applicability of Lifecycle Sustainability Assessment metrics in Uganda's public sector construction projects. 3. Investigate the prospects for integrating Lifecycle Sustainability Assessment metrics into public sector cost management practices. 4. Develop a model for integrating Lifecycle Sustainability Assessment metrics into public sector construction cost management practices.
 Uganda 2026-07-09 18:42:31 2029-07-09 Engineering and Technology Non-Clinical Trial Degree Award
Sseremba Mark
ID: UNCST-2025-R022376
 Performance Management Reforms in Uganda,s Public Service: An Exploration of the Experiences of Key Implementers of Performance Agreement
REFNo: SS4719ES

General objective To explore the experiences of key implementers of performance management reforms – performance agreements in the Uganda public service. Specific objectives of the study The research will address the following specific objectives: 1) To explore the endogenous and exogenous drivers that led to the introduction of performance agreements in Uganda’s public service. 2) To explore what implementers perceive as critical factors responsible for the successful implementation of performance agreements in the Uganda Public Service 3) To explore, from the perspective of implementers, the effect of performance agreements on the functioning of Uganda's public service.
Uganda 2026-01-27 19:32:42 2029-01-27 Social Science and Humanities Non-Clinical Trial Degree Award
Martin Bakunda
ID: UNCST-2025-R022360
 FINANCIAL LITERACY AND FINANCIAL WELLBEING A MODERATED MEDIATED RELATIONSHIP OF SOCIAL CAPITAL AND FINANCIAL STRESS AMONG MICRO AND SMALL BUSINESS OWNERS IN KAMPALA, UGANDA
REFNo: SS5363ES

I. To examine the effect of Financial Literacy on Financial Wellbeing II. To determine the effect of Financial Stress on Financial Wellbeing III. To assess the effect of Social Capital on Financial Wellbeing IV. To examine the effect of Financial Literacy on Financial Stress V. To examine the mediation effect of Financial Stress on the relationship between Financial Literacy and Financial wellbeing VI. To examine the moderating effect of social capital on the relationship between financial literacy and financial stress VII. To assess the moderating effect of social capital on relationship between financial literacy and financial wellbeing VIII. To examine the moderating effect of social capital on the relationship between financial stress and financial wellbeing IX. To analyze the moderation effect of social capital on the indirect relationship between financial literacy and financial wellbeing through financial stress
Uganda 2026-05-28 16:33:41 2029-05-28 Social Science and Humanities Degree Award
Mélissa Berthet
ID: UNCST-2025-R022378
 Commitment to joint action in chimpanzees and gorillas
REFNo: NS1125ES

The goal of the project is to investigate how wild chimpanzees and wild mountain gorillas signal and maintain their joint commitment to joint behavioural actions (for example, travelling together or defending territory).
 France 2026-02-02 18:37:54 2029-02-02 Natural Sciences Non-Clinical Trial Non-degree Award
Frank Kaharuza Mugisha
ID: UNCST-2025-R022389
 ASSESSING THE CONTRIBUTION OF THE SAFE BIRTH AFRICA (SBA) PROJECT IN UGANDA: AN IMPLEMENTATION RESEARCH STUDY ON HEAT-STABLE CARBETOCIN AND TRANEXAMIC ACID FOR POSTPARTUM HAEMORRHAGE PREVENTION AND TREATMENT
REFNo: HS7496ES

The General objective is to generate evidence on the implementation effectiveness and contribution of the Safe Birth Africa project in improving equitable access to and utilization of HSC and TXA for postpartum haemorrhage prevention and treatment in Busoga region and Kampala, Uganda. The specific objectives are 1. To assess the implementation fidelity of SBA interventions (HSC and TXA) across different health facility levels in Busoga region and Kampala. 2. To explore the facilitators and barriers to implementation of the SBA interventions across the pilot sites and regions. 3. To understand health worker experience in the use of HSC for prevention and TXA for treatment of PPH.
Uganda 2026-05-28 15:11:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Davis Kibirige
ID: UNCST-2025-R022421
 Optimal oral glucose-lowering monotherapy in two non-overweight or non-obese African populations with recently diagnosed type 2 diabetes (GLAD STUDY)
REFNo: HS6792ES

Primary Objective
1. To compare the glycaemic response of the three generic and commonly used oral glucose-lowering monotherapies (glimepiride, sitagliptin, and metformin) in non-overweight or non-obese participants with recently diagnosed type 2 diabetes living in Uganda and Cameroon
Secondary Objective
1. To compare the tolerability (measured by discontinuation of therapy within 12 months of treatment initiation) of three generic oral glucose-lowering monotherapies (glimepiride, sitagliptin, and metformin) when used in non-overweight or non-obese adult Ugandans and Cameroonians with newly diagnosed T2D
2. To compare the side effects (including weight change and hypoglycaemia, over 12 months of treatment initiation) of three generic oral glucose-lowering monotherapies (glimepiride, sitagliptin, and metformin) when used in non-overweight or non-obese adult Ugandans and Cameroonians with newly diagnosed T2D.
3. To compare the quality of life and treatment satisfaction, as measured by the diabetes treatment satisfaction questionnaire (DTSQ) and the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), over 12 months of treatment initiation, associated with the use of the three generic oral glucose-lowering monotherapies (glimepiride, sitagliptin, and metformin) in non-overweight or non-obese adult Ugandans and Cameroonians with newly diagnosed T2D.

 Uganda 2026-02-12 12:40:30 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Nshakira
ID: UNCST-2025-R022416
 Comprehensive Immunization Coverage Survey in 54 Districts of Uganda.
REFNo: HS6888ES

1. To estimate the coverage of routine immunization among children aged 12-35 months in the 54 selected districts across the different regions of Uganda. 2. To determine factors associated with immunization uptake and missed immunizations among children aged 12-35 months across the districts of focus. 3. To assess factors affecting the implementation of the immunization program activities, and elaborate the main barriers to equitable and universal service coverage.
Uganda 2026-01-27 19:45:03 2029-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DerrickBukenya Kato
ID: UNCST-2025-R022430
 THE SPATIAL VARIATIONS IN WATER QUALITY AND BIOLOGICAL COMMUNITIES OF SELECTED TRIBUTARIES IN THE UGANDAN PART OF THE LAKE ALBERT BASIN
REFNo: NS1240ES

ii. To determine the spatial variation in the water quality parameters of selected streams and nearshore zones of Lake Albertiii. To determine the in-stream and riparian zone habitat integrity scores at the selected sites along the selected streams
 Uganda 2026-04-29 15:36:31 2029-04-29 Natural Sciences Non-Clinical Trial Degree Award
JOEL KASIBANTE ALBERT
ID: UNCST-2025-R022443
 MIXED-METHODS IMPACT EVALUATION OF THE DIMITRA CLUBS PROJECT IN UGANDA’S AMOLATAR DISTRICT
REFNo: SS4697ES

Main Objective / Purpose The impact evaluation seeks to understand how participation in Dimitra Clubs influences women’s empowerment and social inclusion. It will assess changes in social cohesion—such as trust, community participation, collective problem-solving, and conflict resolution. The evaluation will further examine how the Clubs strengthen women’s agency, confidence, decision-making power, and access to social and economic resources, while also observing shifts in gender norms among both women and men. Lastly, the study aims to determine whether involvement in the Clubs reduces experiences of intimate partner violence. Specific Objectives (Polished & Summarised) 1. To evaluate how the Dimitra Clubs enhance women’s intrinsic agency, including autonomy over income decisions and overall self-efficacy. 2. To explore changes in intra-household gender dynamics, including men’s engagement in domestic roles and how household resources are controlled or allocated. 3. To determine whether participation in the Clubs is associated with a reduction in intimate partner violence. 4. To assess the influence of the Clubs on participants’ social cohesion, focusing on trust, relationships, community participation, and confidence in local institutions.
Uganda 2026-04-10 14:58:12 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Walakira
ID: UNCST-2025-R022446
 Combating Antimalarial Resistance: An AI-Driven Approach to Identify andPrioritize Key Parasite Mutations
REFNo: HS7367ES

1. To use AI-driven variant prediction, structural modeling, and clinical-epidemiological data integration to identify and prioritize Plasmodium falciparum mutations associated with drug and vaccine resistance.

2. To predict the pathogenicity of mutations across the P. falciparum genome.

3. To identify mutations located in active or functionally critical regions of prioritized P. falciparum genes by applying variant effect prediction and protein structure modeling tools.

4. To link predicted pathogenic mutations with available epidemiological and clinical metadata to identify variants of public health importance, including those associated with treatment failure, disease severity, or vaccine response.
 Uganda 2026-06-25 22:18:53 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonah Im
ID: UNCST-2025-R022465
 Assessing the Health, Educational, and Psychosocial Impact of Rainwater Purification Systems in Kijoto Parish, Uganda
REFNo: HS7133ES

The purpose of this research is to evaluate the social, psychological, and health-related impact of newly installed rainwater catchment, purification, and storage systems at three primary schools in Kitojo Parish, Uganda. These systems were implemented by the Healthy Hands Initiative and Raising the Communities in February 2025 to address water insecurity and its associated burdens in rural areas.
This study has the following specific aims:

Aim 1:
Assess the impact of clean water access on community quality of life, mental health, and safety.
We will examine how rainwater systems influence the day-to-day lives of community members, with a focus on time savings, perceived improvements in health and well-being, reduced anxiety around water access, and improved safety (e.g., reduced long-distance water collection, particularly for women and children).

Aim 2:
Explore the effects of clean water systems on educational outcomes and student well-being.
We will investigate how water access affects teacher-reported attendance, student focus, and general classroom dynamics. We hypothesize that improved access to clean water correlates with higher attendance and fewer health-related absences.

Aim 3:
Identify implementation factors that affect system adoption and sustainability.
Using qualitative methods grounded in implementation science frameworks (e.g., RE-AIM or CFIR), we will explore what factors support or hinder successful adoption and long-term maintenance of the rainwater systems. These factors may include local leadership involvement, cultural attitudes, system usability, and perceptions of ownership.

Aim 4:
Compare current water quality with prior community sources.
Water samples will be collected from the new systems and compared with samples from previously used sources to evaluate improvements in water safety.


 USA 2026-04-10 18:49:20 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ochom
ID: UNCST-2025-R022492
 REVENUE DIVERSIFICATION, FINANCIAL PLANNING AND FINANCIAL SUSTAINABILITY OF PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS5076ES

The study will be guided by the following objectives. I. To examine the extent to which grants and donations contribute to revenue diversification and financial sustainability of Uganda’s public universities. II. To assess how tuition and functional fees, as components of revenue diversification, influence the financial sustainability of Uganda’s public universities. III. To analyze the role of research and consultancy services in enhancing revenue diversification and financial sustainability of Uganda’s public universities. IV. To evaluate the contribution of commercial activities and enterprise ventures to revenue diversification and financial sustainability of Uganda’s public universities. V. To examine the mediating role of financial planning in the relationship between revenue diversification and financial sustainability of Uganda’s public universities
Uganda 2026-06-11 12:41:36 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Crispus Tashobya
ID: UNCST-2025-R022506
 INTELLECTUAL CAPITAL AND BUSINESS PERFORMANCE AMONG SMALL & MEDIUM ENTERPRISES (SMEs) IN AGRO-FOOD PROCESSING IN WESTERN UGANDA
REFNo: SS4810ES

i. To assess the effect of structural capital on business performance of agro-food processing SMEs in Western Uganda.
ii. To determine the effect of human capital on business performance of agro-food processing SMEs in Western Uganda.
iii. To analyze the effect of relational capital on business performance of agro-food processing SMEs in Western Uganda.
iv. To examine the mediating effect of innovation on the relationship between intellectual capital and business performance of agro-food processing SMEs in Western Uganda.

 Uganda 2026-02-12 13:38:44 2029-02-12 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Ariho
ID: UNCST-2025-R022515
 Prevalence and Factors Associated with Low Completion Rates of Eight Antenatal Care Visits Among Postpartum Women in Buhweju District, Uganda
REFNo: HS7381ES

1. To determine the proportion of mothers who attended eight antenatal care visits among postpartum women in Buhweju District, Uganda. 2. To examine women related factors associated with low completion rates of eight antenatal care visits among postpartum women in Buhweju District, Uganda 3. To establish the interpersonal factors contributing to low completion rates of eight antenatal care visits among postpartum women in Buhweju District, Uganda 4. To examine institutional factors influencing the low completion rates of eight antenatal care visits among postpartum women in Buhweju District, Uganda
 Uganda 2026-04-10 19:15:07 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Ruth Tullis Carolann
ID: UNCST-2025-R022526
 A Study of the use of Ficus natalensis leaves as an Anthelminthic in Goats
REFNo: A744ES

To observe the effectiveness of F. natalensis as a natural anthelminthic in goats. To evaluate the usefulness of F. natalensis to Ugandan villages
 USA 2026-03-25 11:24:36 2029-03-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Deborah Kirabo
ID: UNCST-2025-R022547
 Documentation of RAHU Peer Education Model
REFNo: SS4727ES

Objective 1: To comprehensively document RAHU\'s Peer Education Model design, implementation mechanisms, and operational approaches across five regions (Kampala, Kasese, Adjumani, Busoga, and Sebei) from 2014 to present

Objective 2: To assess the peer education model\'s performance against its three core program objectives: (a) improving young people\'s access to SRHR information for informed decision-making, (b) reducing risks and promoting individual and collective empowerment about sexual and reproductive health, and (c) strengthening interpersonal communication skills for peer-to-peer SRHR communication

Objective 3: To analyze implementation challenges, success factors, regional adaptations, and lessons learned to generate evidence-based recommendations for model replication, scaling, and policy advocacy.
 Uganda 2026-02-18 12:43:08 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
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