Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Cathlyn  Atukunda
ID: UNCST-2022-R009265
Exploring the implementation of new PrEP methods during periconception, throughout pregnancy, and after childbirth
REFNo: HS6260ES

Aim 1a: Explore preliminary implementation strategies for injectable cabotegravir (CAB) and other long-acting PrEP agents for people of reproductive potential in rural Alabama and Uganda.


Aim1b: Informed by the qualitative findings, we will design a survey to quantify the perceived barriers and facilitators and assess feasibility and acceptability of the implementation strategies proposed in Aim 1a. We propose to survey N~120 key stakeholders (KS) across the two sites.

Approach (Aims 1a-b): Using rapid qualitative methods to analyze in-depth interviews and focus group discussion conducted with ~24 key stakeholders (ministry of health, clinic administrators, clinicians) and ~50 consumers (people of reproductive potential) across the two sites. We will then survey ~120 key stakeholders across sites to assess feasibility and acceptability of the implementation strategies identified in the qualitative work (Aim 2b).

Aim 2. Select implementation strategies for a future adaptive trial through a modified Delphi process.
Approach: Stakeholders will be convened for site-specific group meetings to hear suggestions for implementation strategies and adaptations, and asked rank their preferences. These data and information from the literature will inform the design of an adaptive trial for evaluating implementation strategies for novel PrEP for people of reproductive potential in rural Uganda and Alabama.

Uganda 2025-08-18 13:55:55 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anne Akello Ruth
ID: UNCST-2022-R009131
ASSESSMENT OF OCCUPATIONAL HAZARDS AND HEALTH EFFECTS AMONG WORKERS OF GRAIN MILLS IN SOROTI CITY, UGANDA
REFNo: HS6278ES

1. To identify occupational hazards in work places within grain mills in Soroti city.
2. To establish knowledge, attitudes and practices (KAP)on occupational hazards among workers of grain mills in Soroti city.
3. To examine the status of implementation of OSH policies by owners and workers of the grain mills in Soroti city.
4. To determine the health effects of exposure to occupational hazards among workers of grain mills in Soroti city
5. To establish the factors that influence occurrence of occupational hazards and health effects among workers of grain mills in Soroti city.

Uganda 2025-10-01 12:20:18 2028-10-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Mariam Nanteza Ssesanga
ID: UNCST-2025-R020432
Research Funding for Ugandan Institutions (2015-2025): A decadal analysis and an exploration of institutional sustainability and individual experiences amid recent global funding Cuts.
REFNo: SS4186ES

i. To analyze research funding patterns and trends for Ugandan institutions from 2015 to 2025, examining changes in funding sources, volumes, and allocations.
ii. To explore the perspectives and lived experiences of individual researchers in Uganda regarding the impact of recent funding cuts by the US and other global north funders.
iii. To investigate the actions, strategies, and adaptability measures adopted by Ugandan research institutions to sustain operations and research activities in response to recent global funding reductions.

Uganda 2025-09-12 16:40:30 2028-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Pauline Amuge Mary
ID: UNCST-2023-R005532
LC-REVITALIZE – A Long Covid Repurposed Drug Study
REFNo: HS6370ES

-To assess the efficacy of repurposed drugs compared to their
respective placebos in reducing standardized symptom severity scores
in participants with Long Covid.
-To compare the symptom burden (e.g., anxiety, depression, overall
well-being) in participants with Long Covid treated with repurposed
drugs versus their respective placebos.
- To assess whether symptom burden worsens in participants with Long
Covid treated with study drugs versus placebo, specifically when
symptoms are reported across multiple scales.
- To assess changes in exercise capacity over time of participants with
Long Covid treated with study drugs versus their respective placebos.
- To measure specific Long Covid pathophysiological biomarkers of study
drugs versus their respective placebos.

Uganda 2025-09-12 17:00:13 2028-09-12 Medical and Health Sciences Clinical Trial Non-degree Award
VICTORIA NAKAGIMU MWAZI
ID: UNCST-2025-R020484
FOOD ENVIRONMENT, DIETARY PATTERNS AND NUTRITIONAL STATUS OF SECONDARY SCHOOL TEACHERS IN KAMPALA CITY
REFNo: HS6358ES

To assess the food environment of secondary school teachers in Kampala City, Uganda.
(ii) To analyse the food consumption patterns of secondary school teachers in Kampala City, Uganda.
(iii) To assess the nutritional status and associated factors of secondary school teachers in Kampala city.
(iv) To explore the perceptions of stakeholders on the food environment, diet and the nutritional status of secondary school teachers in Kampala City.

Uganda 2025-11-04 13:42:47 2028-11-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Alinda
ID: UNCST-2025-R020482
PHYSICAL PLANNING AND URBANIZATION IN UGANDA: A CASE OF FORT PORTAL CITY, CENTRAL DIVISION
REFNo: SS4377ES

General Objective (Purpose) of the Study The study is to evaluate the effect of physical planning on urbanization in Fort Portal City, Uganda. Specific Objectives of the Study i.To assess the effect of Urban Design on urbanisation in Fort Portal City. ii.To examine the influence of Enforcement Mechanism on Urbanisation in Fort Portal City. iii.To evaluate the contribution of Monitoring & Evaluation on urbanisation in Fort Portal
Uganda 2025-11-04 13:37:44 2028-11-04 Social Science and Humanities Non-Clinical Trial Degree Award
Patience Atukunda
ID: UNCST-2023-R005832
BUILDING ARTIFICIAL INTELLIGENCE MODELS FOR BREAST CANCER DIAGNOSIS USING CLINICAL, ULTRASOUND AND CYTOLOGY DATA
REFNo: SIR559ES

i To build and evaluate an Artificial Intelligence Model for prediction of breast cancer using clinical features ii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using ultrasound data iii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using cytology data iv To build and evaluate an Artificial Intelligence model to integrate clinical, radiology and pathology findings into one report
Uganda 2025-10-01 12:21:26 2028-10-01 Engineering and Technology Non-Clinical Trial Degree Award
Mary Acila Goretti
ID: UNCST-2025-R020322
COMPARATIVE PERFORMANCE OF THE SMALL EAST AFRICAN ZEBU AND ITS CROSSES WITH TYROLEAN GREY CATTLE IN ASWA RANCH AND LUSENKE STOCK FARM OF UGANDA
REFNo: A653ES

1. To determine morphological traits and structural indices of the Small East African Zebu and its crosses with Tyrolean Grey cattle under on station conditions in Aswa Ranch and Lusenke Stock farm.
2. To determine milk production and growth performance of the Small East African Zebu and its crosses with Tyrolean Grey cattle under on station conditions in Aswa Ranch and Lusenke Stock farm.
3. To determine reproductive performance of the Small East African Zebu and its crosses with Tyrolean Grey cattle under on station conditions in Aswa Ranch and Lusenke Stock farm.

Uganda 2025-11-04 17:55:57 2028-11-04 Agricultural Sciences Non-Clinical Trial Degree Award
Dr. James Wasike Mangeni Byanasaye
ID: UNCST-2020-R008019
DENTAL ANTIMICROBIAL STEWARDSHIP IN UGANDA - DEVELOPING AN EVIDENCE BASED INTERVENTION
REFNo: HS6561ES

Aim: To develop evidence-based, behaviour science informed antimicrobial stewardship intervention aimed at reducing antibiotic prescribing to adult patients for dental issues.
Objectives:
1. To understand the factors that influence antibiotic prescribing by health care practitioners to adult patients for dental issues.
2. To explore the perspectives of patients seeking dental care on the use of antibiotics for dental issues.
3. To explore community stakeholders' perspectives on the use of antibiotics for dental issues
4. To co-produce an evidence-based, behaviour science informed dental antibiotic stewardship intervention for Uganda.


Uganda 2025-10-24 17:32:56 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Caroline Agabiirwe Noel
ID: UNCST-2025-R020394
Development and effectiveness of the Better Health media campaign on maternal and child health-seeking behaviours in Uganda.
REFNo: HS6737ES

1. To explore the knowledge, attitudes, and practices among the target audiences related to ANC, PNC, malaria vaccine and diarrhoea management in children. 2. Assess the acceptability of the campaign among the target audience, exploring attitudes of the target audience towards the campaign and mechanisms of campaign impact. 3. Run a controlled quantitative evaluation study to assess the impact of the campaign on knowledge, beliefs, intentions and behaviours related to ANC, PNC and malaria vaccine. 4. To complement the quantitative study with controlled time series analysis of routine DHIS2 data, to examine shifts in trends in treatment seeking, ANC uptake, PNC uptake, and malaria vaccine uptake that may be attributable to the campaign.
Uganda 2025-11-07 5:08:21 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Atim
ID: UNCST-2020-R014964
Effects of biomass fuel usage on indoor air quality and associated respiratory health of women and children in Northern Uganda
REFNo: HS6606ES

1.To analyse the trends of biomass fuel usage in Uganda from 2001 to 2022. 2.To determine the factors associated with respiratory symptoms among women and children in rural and urban areas of Northern Uganda. 3.To quantify the levels of personal exposure of women to air particles (PM2.5, PM10) in the different micro-environments. 4.To explore the perspectives of the community and stakeholders regarding the impacts of cooking fuels.
Uganda 2025-11-26 14:26:18 2028-11-26 Medical and Health Sciences Non-Clinical Trial Degree Award
HAKIIMU KAWALYA
ID: UNCST-2025-R020311
Sickle Cell Modifier Genes Across Diverse Human Populations
REFNo: HS6710ES

1) To profile the most common fetal hemoglobin associated sickle cell disease modifier genes 2) To determine population specific gene expression patterns of fetal hemoglobin associated sickle cell disease modifier genes 3) To characterize inter-population Allele Frequencies of fetal hemoglobin associated sickle cell disease modifier gene variants 4) To analyze selection signals in fetal hemoglobin associated sickle cell modifier genes using human whole genome sequencing data
Uganda 2025-11-13 15:27:46 2028-11-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Kamiza Patrick
ID: UNCST-2025-R020340
Organizational Justice, compassionate Leadership, Career Motivation and Compensation satisfaction among Academic Staff in Public Universities in Uganda.
REFNo: SS4555ES

i) examine the relationship between organizational justice and compensation satisfaction amongst staff in public universities in Uganda:
ii) assess the relationship between compassionate leadership and compensation satisfaction amongst academic staff in public universities in Uganda;
iii) examine the relationship between career motivation and compensation satisfaction amongst academic staff in public Universities in Uganda;
iv) determine the relationship between organizational justice and career motivation amongst academic staff in public universities in Uganda;
v) examine the relationship between compassionate leadership and career motivation amongst academic staff in public universities in Uganda;
vi) examine the mediating role of career motivation on the relationship between organisational justice and compensation satisfaction;
vii) examine the mediating effect of career motivation in the association between compassionate leadership and compensation satisfaction.

Uganda 2026-02-02 18:33:41 2029-02-02 Social Science and Humanities Degree Award
FRANCIS  AMAYOA ANYAKA
ID: UNCST-2024-R003877
INTEGRATING ENVIRONMENTAL SUSTAINABILITY INTO RESEARCH ETHICS REVIEW IN UGANDA: PERSPECTIVES OF RESEARCH ETHICS COMMITTEE MEMBERS.
REFNo: HS7784ES

General Objective To assess the awareness, attitudes, and practices of RECs regarding environmental sustainability, and to identify practical strategies for enhancing its integration into research ethics review. Specific Objectives 1. To assess awareness among REC members regarding environmental sustainability in research. 2. To examine the attitudes and perceptions of REC members toward incorporating environmental sustainability into ethics review processes. 3. To assess current practices for integration of environmental considerations into REC ethics review processes. 4. To identify the barriers and facilitators that influence the integration of environmental sustainability into research ethics review by RECs. 5. To propose strategies for strengthening ethical oversight systems to effectively incorporate environmental sustainability into research governance.
Uganda 2026-05-28 15:58:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clara Kansiime
ID: UNCST-2020-R014325
DECOLONISING ACCOUNTABILITY PRACTICES IN NGOS: INSIGHTS FROM UGANDA
REFNo: SS4671ES

1. To review existing debates on downward accountability within the Ugandan NGO sector, exploring how accountability practices are conceptualized and implemented. 2. To examine the perspectives of local NGO practitioners, beneficiaries, and relevant stakeholders on accountability in their contexts, capturing how these practices are experienced and understood on the ground. 3. To identify and document community practices, values, and participatory approaches that could inform culturally and contextually relevant accountability mechanisms in Ugandan NGO management. 4. To propose context-sensitive accountability pathways that challenge colonial legacies and promote sustainable, equitable, and community-owned development practices
Uganda 2025-12-18 17:12:50 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
Pauline Amuge Mary
ID: UNCST-2023-R005532
Bedaquiline Roll-out Evidence in Contacts and People Living with HIV to prevent TB (BREACH-TB)
REFNo: HS6975ES

2.1.1.To estimate the safety of 1BDQ and 3HP among
adult, adolescent, and child CCs of DS-TB Index
Patients at high risk of developing TBD, as well
as adult and adolescent PLHIV in high TB burden settings

2.1.2To estimate the safety of 1BDQ and 6 months of
levofloxacin (LFX) among adult, adolescent, and
child CCs of RR-TB Index Patients at high risk of
developing TBD
2.1.3 To estimate on-time treatment completion of
1BDQ and 3HP among adult, adolescent, and
child CCs of DS-TB Index Patients at high risk of
developing TBD, as well as adult and adolescent
PLHIV in high TB-burden settings
2.1.4To estimate on-time treatment completion of
1BDQ and 6 months of levofloxacin (LFX)
among adult, adolescent, and child CCs of RRTB Index Patients at high risk of developing TBD
Uganda 2026-02-05 22:05:22 2029-02-05 Medical and Health Sciences Clinical Trial Non-degree Award
SANDRA NABATANZI
ID: UNCST-2025-R020333
Improving civil registration and vital statistics through implementation of an integrated digital maternal and perinatal death registration system at health facilities in Uganda
REFNo: HS6898ES

1. To evaluate existing information systems for maternal and perinatal death registration, including mapping data flows, and identification of barriers and enabling factors for use of an integrated digital death registry. 2. To co-design implementation strategies to improve acceptability and use of an integrated digital maternal and perinatal death registry in health facilities in Mukono district. 3. Evaluate implementation outcomes specifically, feasibility, acceptability and fidelity of using an integrated digital death registry to capture maternal and perinatal deaths and assess data quality of maternal and perinatal death reporting in health facilities in Mukono district.
Uganda 2026-01-27 19:37:43 2029-01-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Martin Okello
ID: UNCST-2025-R020344
INVESTIGATION OF PLANT-BASED MOSQUITO REPELLENTS FOR VECTOR-BORNE DISEASE CONTROL, ESPECIALLY MALARIA IN RURAL UGANDA: A MIXED METHODS APPROACH
REFNo: HS7051ES

4. To gain more understanding through existing literature/research about Lantana camara (LC) plants and other repellent/herbal plants in relations to vector borne diseases, especially malaria control/prevention in rural Uganda.
5. To collect information regarding attitude, knowledge, beliefs, and behaviours about Lantana camara (LC) plants and possibly other repellent plants in relation to malaria prevention in rural Uganda.
6. To explore factors associated with implementing the use of plant-based repellent products like Lantana plant extracts or other repellant plants as alternatives to control or prevent malaria in rural Uganda, including the feasibility, acceptability and sustainability of such approaches.

Uganda 2026-02-18 12:32:51 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Shango Patience  Jakheng Emmanuel
ID: UNCST-2025-R020526
WHOLE-GENOME CHARACTERIZATION AND PHYLOGENETIC ANALYSIS OF HUMAN PAPILLOMAVIRUS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE AT ISHAKA ADVENTIST HOSPITAL, WESTERN UGANDA.
REFNo: HS7175ES

1. To determine the prevalence of HPV infection among pregnant women attending antenatal care at Ishaka Adventist Hospital. 2. To characterize the genotype distribution and genomic diversity of HPV strains circulating among pregnant women in this population. 3. To identify risk factors associated with HPV infection among pregnant women attending antenatal care at Ishaka Adventist Hospital. 4. To characterize HPV genomic integration patterns using whole-genome sequencing, stratified by HIV status and HPV phylogenetic clade. 5. To quantify E6/E7 oncogene expression using transcriptomic analysis and assess its relationship with HPV genomic status (integrated versus episomal). 6. To determine the phylogenetic relationships of HPV strains detected among pregnant women attending antenatal care at Ishaka Adventist Hospital.
Nigeria 2026-04-20 11:04:16 2029-04-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Judith Akello
ID: UNCST-2022-R009134
Negotiating Motherhood in Gendered Cultural Spaces: Breastfeeding Student-Mothers and Staff at Lira University Through Performing Arts and Culture
REFNo: SS5146ES

• To document the institutional challenges faced by breastfeeding student-mothers and staff at Lira University within six months.
• To analyse how cultural beliefs and gender norms influence breastfeeding practices
among these mothers within eight months.
• To develop context-specific recommendations for institutional policies and programs that
support breastfeeding mothers in higher education by the end of twelve months.
Uganda 2026-04-29 15:33:41 2029-04-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
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