Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joseph Ngonzi
ID: UNCST-2019-R001579
Development of Software to Rapidly Assess Placenta Images at Birth
REFNo: HS3159ES

1. To develop AI-based software that accurately identifies a range of placental features and diagnoses from digital images.
2. To improve the reliability and robustness of the software under different conditions (e.g., different cameras, lighting).
3: To test and quantify improvements in software accuracy with medical data input (e.g., infant sex, delivery mode, and birth weight).

Uganda 2023-12-21 20:48:48 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
OPTIMIZATION, VALIDATION AND ASSESSMENT OF FEASIBILITY AND ACCEPTABILITY OF HPV TESTING USING CODA
REFNo: HS4734ES

To develop and establish a novel rapid multi-modal algorithm (CANOPY) for screening and treatment of cervical cancer integrating multiple (CODA, VIA, ML) screening modalities to improve diagnostic yield. ,To gather design feedback to improve CODA workflow and device design, and refine CODA device, assay, and workflow using this critical feedback provided by Ugandan stakeholders,To evaluate the feasibility and acceptability of CODA in a clinical setting in Uganda based on feedback from clinical, public health, and patient stakeholders,To evaluate HPV testing using CODA in comparison to other (VIA, ML, ATILA System) devices for clinicians and patients engaged in community-based cervical cancer screening. ,To determine the diagnostic accuracy of CODA a clinical setting, using FP rate and comparison with gold-standard HPV tests and cytology,We will optimize, validate and assess the feasibility and acceptability of HPV testing using CODA and develop and validate a multimodal cervical cancer screening algorithm to optimize diagnostic yield (CANOPY).,
Uganda 2024-12-10 15:49:00 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
PACO Heart Evaluation and Risk Tracking (PACO-HEART)
REFNo: HS5985ES

Main objective: 1. Determine whether women with HIV taking DTG during pregnancy are more likely to experience hypertension, have elevated cardiovascular disease risk factors, and demonstrate vascular dysfunction postpartum.

Sub-Objectives:
1. Prospectively assess postpartum cardiovascular disease risk factors in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
2. Assess vascular function in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
3. Quantify and compare biomarkers of cardiovascular disease in peripheral plasma in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
4. Examine association between placenta pathological features (already measured in PACO cohort participants) and postpartum hypertension, vascular function, and biomarkers of cardiovascular disease


Uganda 2025-09-17 13:26:00 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mahsa Abassi
ID:
Utilization of SMS Messaging Services to Improve Retention in Care of HIV-Infected Individuals in Uganda Short Title: SMS-2-Retain (S2R)
REFNo: SS62ES

The objective of the study is to determine if mobile health (mHealth) technology (text/voice-messaging services) is an effective method of improving retention in care for newly diagnosed HIV-infected individuals enrolling into care, as compared to standard of care. This is a pilot, non-blinded, randomized trial of mobile health implementation into routine HIV care. This pilot trial will be focusing on 1) two-week retention in care of all HIV-infected participants from enrollment and followed by 2) participants who have been found to have cryptococcal antigenemia, a population of participants most at risk for early morbidity and mortality.
USA 2017-03-07 2020-03-07 Social Science and Humanities Non-degree Award
Lucia Rost Aline
ID:
Negotiating time use: an inter-generational mixed methods approach to intra-household decision-making on care and domestic work in Northern Uganda
REFNo: SS59ES

My research develops an intergenerational approach to understanding intra-household decision-making on time use, especially with regards to time spent on care work—in the post-conflict setting in Northern Uganda.
Germany 2017-06-13 2020-06-13 Social Science and Humanities Degree Award
Bruno Braak Jim
ID:
Access to land and justice among South Sudanese refugees in Uganda
REFNo: SS67ES

This proposed research would contribute to my PhD dissertation. It would draw on a prior period of three months of intensive and collaborative field research in South Sudan as a basis to compare current perceptions and practices with. The objective of this proposed research would be to discover the changes and continuities in Western Equatorians’ access to land and justice mechanisms. Doing so, it hopes to shed light on the impact of the process of forced displacement to Uganda. Conceptually, this research would draw on notions and practices around authority, identity and property. Special attention will be devoted to the differentiated impact according to gender, ethnicity, and socio-economic background.
Netherlands 2017-05-09 2020-05-09 Social Science and Humanities Degree Award
Joshua Nfambi
ID:
Effect of Moringa oleifera extracts on the HIV model: A study of nutrient bioavailability and immunological responses
REFNo: HS46ES

1. To assess the presence and quantity of micronutrients in Moringa oleifera leaf extracts 2. To determine the bioavailability of the micronutrients in Moringa oleifera in a Murine model 3. To establish the effect of Moringa oleifera leaf extracts on HIV virus replication in T-lymphocytes and macrophages 4. To determine the effect of Moringa oleifera leaf extracts on secretion of chemokines, IL1, 12 TNF α and INF γ in HIV infected cells 5. To determine the effect of Moringa oleifera leaf extracts on the cell mediated immune system of a humanized HIV murine model
Uganda 2017-04-25 2020-04-25 Medical and Health Sciences Non-degree Award
Madelyn Prevost
ID:
The Entrepreneurial Spirit: Crafting subjects with regimented health and religion
REFNo: SS122ES

This project is intended to further the knowledge on HIV/AIDS, Catholicism, Non-Governmental Organizations, poverty, and work in a Ugandan context as globalization, greater access to medicine, and modernity change the cultural landscape. In addition to furthering scholarly knowledge, this project will also, ideally, help the site organization, Reach Out Mbuya remain relevant in the changing climates of donor funding, client needs, and HIV prevalence rates. Reach Out is a Catholic-based HIV/AIDS organization that seeks to provide holistic care to clients and their families through medical care, material support, subsistence projects, counseling, HIV prevention, and peer support. In Kampala, Reach Out has community sites in Mbuya, Banda, and Kinawatak; they also have an additional site in Kasaala. I will likely draw all of my participants from the Mbuya, Banda, and Kinawataka site locations; as a volunteer, I will spend most days at Mbuya, but also do work in Banda and Kinawataka sites weekly. Therefore, I will be more known to staff and clients at these locations, making recruiting participants smoother. Building off literature that demonstrates how an HIV diagnoses affects a person’s sense of self and habits (Wekesa and Coast [2013]; McGrath et al [2014]); Whyte [2014]; Bartos and MacDonald [2000]), I propose that HIV, as well as comprehensive aid programs can have unique and varied affects on a person’s employment and livelihood. Adding to this argument, I will draw on literature dealing with subject formation (how a person’s identity and behaviours are formed and changed through processes and interactions), both in secular and Christian contexts (Foucault [2000]; Koopman [2013]; Skinner [2012]; Tambling [1990]; Norget, Napolitano, and Mayblin [2017]). Using this literature, I will argue that it is a combination of the regimented HIV/AIDS treatment schedule and Catholic belief and practice encouraged and facilitated by Reach Out that creates a socially responsible and productive subjects in their clients. Working from this hypothesis, my project asks three primary questions: (1) How might being HIV positive affect an individual’s work, livelihood, and/or employment, and what role might religion play in the extent of these effects? (2) How does Reach Out’s comprehensive, holistic-based approach complement services provided by the government? (3) How does being HIV positive affect one’s social and/or economic standing, and one’s capability to remain in care?
Canada 2017-11-20 2020-11-20 Social Science and Humanities Degree Award
marie nanyanzi
ID: UNCST-2019-R001553
Point Of Entry Sauti Za Wananchi (Voices of the citizens)Extension Survey
REFNo: SS468ES

To understand the COVID-19 effects on the citizens’ experience and key services they receive during this era of COVID-19 especially ▪ Establish citizen access to safe water; ▪ Establish citizen access and usage of health services and knowledge, Attitudes and Practices (KAPs); ▪ Find out level of participation/involvement/interaction in development and public activities /institutions; ▪ Find out access and usage of financial services amongst citizens; ▪ Find out how; what and when citizen access different type of information including government and development information. ▪ Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different guidelines, policies; laws and regulations etc
Uganda 2020-09-28 2023-09-28 Social Science and Humanities Non-degree Award
marie nanyanzi
ID: UNCST-2019-R001553
Sauti Za Wananchi (Voices of citizens) Baseline Survey Panel II
REFNo: SS887ES

o Gather opinions from the citizens on the key services they receive especially
ï‚§ Establish citizen access to safe water;
ï‚§ Establish citizen access and usage of health services;
ï‚§ Establish the citizens attitudes and practices on issues related to COVID-19
ï‚§ Find out level of participation/involvement/interaction in development and public activities /institutions;
ï‚§ Find out access and usage of financial services amongst citizens;
ï‚§ Find out how; what and when citizen access different type of information including government and development information.
ï‚§ Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different policies; laws and regulations etc

Uganda 2021-07-05 2024-07-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kate Scow
ID:
Innovations  in Dry Season Horticulture for Women and Smallholders in East Africa -Production and Marketing for income, nutrition, and climate resilience
REFNo: A14ES

Dry season vegetable production has been identified as a high priority in the largely rainfed (>97%) agricultural systems of Uganda. Off season vegetable supplies are currently inadequate to meet human nutritional needs. As rainfall patterns become increasingly unpredictable and rapid population expansion places more pressure on food systems, demand for vegetables will further outstrip supplies. This spin-off project builds on the team’s previous participatory work in Uganda to convene stakeholders from public and private sectors and develop innovations in small scale dry season vegetable production for women farmers in East Africa. We will develop a research and development approach resulting in release of horticulture irrigation innovations tested at five ‘innovation sites’ over three field seasons in Eastern Uganda and create a framework for local public and private sector organizations to develop small scale irrigation systems. We will work closely with smallholder women farmers who are often excluded from irrigation and marketing developments. We will: i) work at five locations over three dry seasons to test dry season vegetable production systems with farmers, research partners, district staff, NGO partners, and university students, ii) assess agronomic, economic, market, nutrition, and gender impacts of the innovations; and iii) develop scale-out options for the most promising technologies. Ugandan partners include two regional NGOs, three institutes of the National Agricultural Research Organization, and one university. Development of a co-innovation systematic approach for assessing and supporting innovations in dry season vegetable production will strengthen small scale farmer enterprises targeted to local markets and family consumption.
USA 2017-10-31 2020-10-31 Agricultural Sciences Non-degree Award
Florence Brisset-Foucault
ID:
Registering and Identifying People in Uganda A Historical Approach
REFNo: SS210ES

Today, norms and practices of biometric identification are objects of global fascination, curiosity, anxiety or scrutiny. Yet, in the case of Africa, identification documents have hardly been central to scholarship. In order to fill this important gap, this study proposes to focus on the history of official/administrative documents of identification in Uganda, as objects of governmentality (Foucault, 2004). A great variety of identification documentation will be included, as empirical objects of study: birth certificates, voters’ cards, introduction letters by Local councils, party-membership cards, as well as other forms of nominative documentation such as land certificates and drivers’ licenses. The idea is that the daily uses of these objects and the popular representations attached to them will inform us on the parameters of public action, ordinary social life, the imagination of identities and civic cultures. By better understanding Ugandans' previous experiences of identification, it is expected that this research will inform best practices in terms of the documentation and verification of identities, and of the implication of these processes on the State and on society.
France 2019-01-15 2022-01-15 Social Science and Humanities Non-degree Award
Sandrine Perrot
ID: UNCST-2019-R001546
The Bureaucratisation of Legal Identities in colonial and post-colonial Uganda: A Socio-History of State Registration and Documentation of Individuals
REFNo: SS2227ES

My main objective is to generate original insights on the construction of bureaucratic knowledge and techniques of identification and their impact on state construction and practices of citizenship in Uganda. Our goal is to
1. Identify the (un)favourable contexts for the introduction of identification policies
2. Map the players involved in identification over time
3. Highlight the changes in the instruments of identification
4. Examine the circulation of these practices
5. Observe the impact of state identification and registration on the practices of citizenship and the relation to the state
At this stage of my research, I would like to focus on three non-exclusive lines of enquiry: the debate surrounding the first identity cards during late colonialism; the documentation of non-indigenous people, and in particular the citizenship crisis of Asians in the 1960s and 1970s; and finally, the intense periods of identification during electoral periods, and more specifically the processes of voter registration.

France 2024-02-05 13:28:32 2027-02-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Iain Darbyshire Andrew
ID:
Identifying Tropical Important Plant Areas in Uganda
REFNo: NS11ES

Tropical Important Plant Areas (TIPAs) are sites of global importance for conserving the world’s plant diversity, measured through three criteria: threatened species, threatened habitats and high botanical richness. This project will support the identification of TIPAs in the forests of west and central Uganda through conducting field surveys of key sites, selected through prior analysis of herbarium data for Uganda. For each site, we will assess its current status including how intact the forest habitats are, what management practices are in place and what threats are evident. Species of high conservation importance will be specifically targeted, and an assessment made of their abundance at each site. Rapid species inventories, including collection of herbarium specimens, will also be carried out particularly at lesser known forest sites. The field data accumulated will feed into the identification of TIPAs based on the presence of threatened species, threatened habitats and assemblages of important species including those of socio-economic value; these will be published online through the IPA database. The current proposed period of fieldwork is a pilot phase of a wider TIPAs project and will focus on selected sites in the southwest of Uganda. It is envisaged that this pilot will support the development and funding of a larger project on TIPAs in Uganda.
UK 2017-04-25 2020-04-25 Natural Sciences Non-degree Award
Aaron Mulyanyuma Ayeta
ID:
Political parties influencing Uganda's Public Policy Formulation in nascent Hydrocarbon Industry.
REFNo: SS74ES

i. Examine the influence of ideologies of political parties on public policy formulation process in Uganda’s hydrocarbon industry. ii. Assess the influence of political parties’ manifestos and Parliamentary caucuses on Public Policy formulation in hydrocarbon industry in Uganda. ii. Assess the influence of political parties’ manifestos and Parliamentary caucuses on Public Policy formulation in hydrocarbon industry in Uganda. iii. Assess the effectiveness of political party representation in Parliament and their influence public policy formulation in hydrocarbon industry in Uganda. iv. Evaluate challenges affecting political parties in influencing public policy on hydrocarbon industry in Uganda.
Uganda 2017-06-20 2020-06-20 Social Science and Humanities Degree Award
Travis Lybbert
ID:
Innovation & Intellectual Property Policy in the Ugandan Agri-Food Sector: Insights from coffee seed supply chains and tropical fruit processing
REFNo: A16ES

1. To understand the role of innovation and intellectual property (IP) in the Ugandan agricultural sector 2. To identify business, technical, institutional, and policy constraints that limit or otherwise dilute the impact of agricultural R&D, innovation and technology diffusion in the Ugandan agricultural sector
USA 2017-06-19 2020-06-19 Agricultural Sciences Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
MYCOPLASMA PNEUMONIA AMONG HIV-EXPOSED AND UNEXPOSED CHILDREN IN UGANDA: BURDEN, GENOTYPES, RISK AND OUTCOME
REFNo: HS56ES

1.To determine the burden of atypical bacterial pneumonia among HIV-exposed and unexposed children with respiratory illnesses in Mulago hospital. 2.To determine the risk factors for atypical bacterial pneumonia among children with acute respiratory symptoms 3.To determine the outcome of children with atypical pneumonia 4.To describe the relationship between the genotypes of Mycoplasma pneumoniae and resistance to macrolide antibiotics.
Uganda 2017-06-21 2020-06-21 Medical and Health Sciences Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Improving neonatal outcomes through early detection and management of hypoxaemia: The role of routine pulse oximetry
REFNo: HS132ES

1.To evaluate the effect of routine pulse oximetry on neonatal outcomes in the first 24 hours of life. 2.To determine the utility of pulse oximetry compared to clinical signs in detection of hypoxaemia in neonates with possible serious bacterial infections at lower level facilities 3.To assess the feasibility and acceptability of routine pulse oximetry by healthcare workers and caretakers of newborn babies. 4.To determine the cost-effectiveness of routine pulse oximetry in identifying neonates with hypoxaemia. 5.To describe the maternal factors that predict hypoxaemia in the newborn babies
Uganda 2020-03-06 2023-03-06 Medical and Health Sciences Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Evaluating the implementation and clinical outcomes of a mobile health tool to guide management of acute respiratory illnesses in young children
REFNo: HS2004ES

1.To evaluate outcomes of implementation following deployment of the refined Acute Lower Respiratory Illness Treatment Evaluation (ALRITE) mHealth decision support tool in routine clinical practice in two primary care health facilities in Uganda.

2.To further refine the ALRITE user interface, algorithm, and implementation strategy using feedback from objective 1 in order to create a fully functional mHealth application ready for use in primary care facilities in Uganda.

3.To explore clinical and care delivery outcomes, in children aged 1-59 months, before and after ALRITE deployment.

Uganda 2022-08-01 13:20:32 2025-08-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Children’s Air Pollution Profiles in Africa (CAPPA)
REFNo: HS1695ES

• To collect personal air pollution exposure data, activity profiles, and lung function measurements from a total of 420 children with asthma symptoms aged between 12 and 16 years in 7 African cities.
• To analyse personal air pollution data for exposure patterns and peak exposures, and to compare air pollution as well as activity profiles of children in relation to their socioeconomic and geographical backgrounds both within and between countries and compare with measured data from school-age children in London
• To explore potentially detrimental effects of air pollution, and feasibility of mitigation strategies in children with asthma symptoms.


Uganda 2022-01-14 2025-01-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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