Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Elizabeth (Betsy) Ness-Edelstein Ann
ID:
Cooperative Development Program Evaluation
REFNo: SS1664ES

Assess how the specific work of Health Partners in Uganda is contributing to the overall program objectives,● Contribute to the evidence base on effective cooperative development approaches.,● Identify the assumptions or gaps in the project’s design or management approach to help inform a new project design,● Illuminate ways in which the entire project is making progress toward the stated Project Purpose or not,
USA 2023-03-21 3:04:41 2026-03-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jennifer  Kealy
ID:
Community Engagement in Paediatric Biobanking Governance in Uganda.
REFNo: SS1651ES

The aim of this study is to provide IARC and the Ugandan Government with actionable recommendations concerning the development of paediatric biobanking guidelines. The primary objective is to identify the key ethical issues/concerns for researchers, laboratory staff, and health authorities in Uganda, specifically related to public trust in biobanking, and how trust/ trustworthiness could be addressed in paediatric biobanking governance as well as how the community might be engaged.
• Does it hold true that trust/ trustworthiness is contextual and that effectively would preclude any harmonisation of guidelines for biobanking? Or is there any common ground on which to build global /international guidelines,
• What are the gaps in biobanking in Uganda, particularly with respect to paediatric biobanking and,
• How can Uganda create paediatric biobanking guidelines that reflect the needs identified by communities and what would this look like, and,
• How can biobanks show they are trustworthy through their governance and what does that look like to Uganda? Is it sufficient to be transparent and accountable or are other cultural/economic/religious/aspects that parents consider in their assessment of trust in a biobank?
• How can ethical considerations related to biobank governance be addressed in an inclusive, collaborative and deliberative manner

USA 2023-03-16 12:41:09 2026-03-16 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Verdolin
ID:
Establishing a Long-Term Behavioral and Ecological Monitoring Research Program in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park
REFNo: NS500ES

1) Understand the factors contributing to within and between group variability in parasite infection and transmission; 2) Characterize the diet of mountain gorillas across different habitats in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 3) Explore habitat use and spatial dynamics of mountain gorillas in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 4) Collaborate with UWA to yield insights critical for the protection and management of mountain gorillas and other species in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 5) Characterize the biodiversity of Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park, including genomics of multiple species using opportunistically collected fecal samples. These species include but would not be limited to forest elephants and pangolins.
USA 2023-03-16 12:39:44 2026-03-16 Natural Sciences Non-Clinical Trial Non-degree Award
Jesse Rudy Lynn
ID: UNCST-2023-R008208
Prevalence of property Grabbing among widows in Uganda
REFNo: SS1677ES

To establish the total number of people protected in the different project areas districts as a result of Redeem’s program interventions., 1)To understand the indirect consequences of attempted and successful land/property grabbing for widows and orphans in the aftermath of the events, 2)To ascertain the criminal, violent or other means used by perpetrators to victimize widows and orphans through grabbing property or land in Uganda., 3)To determine the prevalence of property grabbing from widows in targeted areas of Uganda, 4)To measure the annual burden of property grabbing in the selected case work areas ,
USA 2023-04-03 15:40:08 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vesall Nourani
ID: UNCST-2022-R009221
Impact of on-demand irrigation service : Evidence from Uganda
REFNo: SS2112ES

Do certain intermediaries (providers of agricultural inputs) facilitate efficient information aggregation and dissemination of farming knowledge between farmers?,
USA 2024-08-05 13:11:25 2027-08-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emma Thurau G
ID: UNCST-2023-R007945
Balancing nutrients and toxins in Black and White colobus monkey(Colobus guereza) diet
REFNo: NS521ES

1. Determine if black and white colobus monkeys use sensory information to select their foods. 2. Determine how plant secondary metabolites (toxins) and nutrients impact black and white food selection and tree visitation rates.
USA 2023-06-30 12:47:56 2026-06-30 Natural Sciences Non-Clinical Trial Degree Award
Zeina Makhoul
ID: UNCST-2022-R009779
Nutrition Assessment for Children with Disabilities and Children without Family Care
REFNo: HS2826ES

The study purpose is to fill longstanding gaps in data on nutrition and feeding for children with disabilities and children living in childcare institutions in Uganda. Our overall hypothesis is that children with disabilities and children living in institutions in Uganda have very high rates of malnutrition, face significant barriers to accessing appropriate nutrition services and support, and merit increased prioritization in policies, practices, and investments. Our objectives are to: 1. Estimate the prevalence of malnutrition, feeding difficulties, and inappropriate feeding practices among children with disabilities and children living in institutions. 2. Assess the perceived barriers to adequate nutrition and feeding among families of children with disabilities and children living in institutions. 3. Understand nutrition and feeding-related support needs of children with disabilities, children living in institutions, and their caregivers 4. Identify the gaps and opportunities in nutrition and feeding services and policies for children with disabilities and children living in institutions; and disseminate recommendations to inform relevant policies and practices.
USA 2023-06-20 11:37:36 2026-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jedediah Silver
ID: UNCST-2023-R007939
The Effects of Cassava Drying Technology on Commercialization and Consumption Smoothing
REFNo: SS1700ES

The main goals of the pilot RCT are to ascertain the technical efficiency of the machines, the viability of the model where agents operate the machines and charge a fee for drying, and to observe how harvest and sales timing, consumption and cropping decisions change when farmers gain access to drying technology. In addition, we will explore additional mechanisms including varying the contract structure, and getting a sense of which channels are most salient to focus on (e.g. how likely we would be to detect effects on intertemporal smoothing beyond addressing the barriers to adoption to a seemingly profitable technology).
USA 2023-04-20 21:05:53 2026-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emily Brownell
ID:
Stories from the Substrate: East African History from the Soil
REFNo: SS1870ES

“Stories from the Substrate” takes shape around several research questions but most fundamentally it asks: What might the history of East Africa look like if we start from the soil? Starting from the soil suggests a point of view, and a trajectory as well as a subject. Together, this offers an opportunity to rework some of the well-trod territory of East African historiography, highlighting new themes and subjects. In African history, scholars have overwhelmingly trained their attention on people and events rather than thinking from and with nonhuman things. What then, comes into focus when we work from the soil, bringing together unlikely stories from which to consider the region’s history? Divided into three parts, this project gathers twentieth century histories of how East Africans have been engaged with animals, plants, and minerals through the substrate.[2] Together, these histories reveal narratives of labor, health, science, and environments by focusing on everyday negotiations of life in the region. Working from government archives, scientific studies, travelers accounts, and oral history interviews to write a series of thematic chapters, this project looks to the relationship between people and soil to build a non-elite history of the region. In starting from the soil, this project is important not just for the stories and actors it highlights, but also what it decenters. In the case of East Africa, this means eliding the ethnic and racial logics of the colonial archive, decentering political events and figures that have dominated the region’s historiography, and reworking narratives of environmental change that centre on colonial development schemes.
USA 2023-08-03 16:00:15 2026-08-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Courtney Blair
ID:
Understanding Ugandan Smallholder Farmers’ Perspectives on Risk in the Context of Input Adoption
REFNo: SS1724ES

To understand how agribusiness interact with smallholder farmers and the types of information they provide,To understand how idiosyncratic shocks impact rural households' ability to purchase agricultural inputs,
USA 2023-09-27 17:47:11 2026-09-27 Social Science and Humanities Non-Clinical Trial Degree Award
Dean Karlan
ID:
Sustainable Market Inclusive Livelihood Pathways to Self-Reliance (SMILES)
REFNo: SS1737ES

Leverage community knowledge to improve program impacts by allocating asset transfers to groups instead of individuals,Evaluate the impact of asset transfers on program participants,Evaluate the impact of MSD on households who are targeted by MSD but not eligible for the graduation program,Evaluate the impact of the graduation program with MSD on program participants,Integrate market system development within the graduation program,Improve cost-efficiency of interventions,Improve efficiency of allocation of capital,
USA 2023-07-19 11:08:08 2026-07-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
James Russell Michael
ID:
Fire and Climate in the Rwenzori Mountain National Park
REFNo: NS531ES

To develop a long-term record of fire in high-elevation areas of the Rwenzori Mountain National Park. With this record, we will investigate the relationship between fire and climate change through time. Our ultimate objective is to determine whether changes in air temperature cause changes in fire frequency through time. This will allow us to better predict changes in fire regime in the future.
USA 2023-05-11 15:00:00 2026-05-11 Natural Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Validating a Measure of Girls’ Agency: A Five-Country Validation & Adaptation of the AMPLIFY Agency Survey
REFNo: SS1726ES

Determine measurement invariance of the AMPLIFY Agency measure across study countries to assess the comparability of derived scores across different countries.,Assess the validity of use of the AMPLIFY Agency survey as a pre-post program outcome evaluation measure overall and in each study country.,Assess the content and construct validity of the AMPLIFY Agency survey as a four-dimension measure of adolescent girls’ agency in each of the 5 study countries (Kenya, Tanzania, Rwanda, Uganda and Malawi).,Assess the reliability of the AMPLIFY Agency survey as a measure of adolescent girls’ agency in each of the 5 study countries (Kenya, Tanzania, Rwanda, Uganda and Malawi).,
USA 2023-05-31 15:26:05 2026-05-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kelsey Morgan Babikov Rae
ID:
Adapting and Piloting a Survivor-Led Case Management Tool ("Freedom Greenlight")
REFNo: SS1827ES

2. The research aims to pilot the Freedom Greenlight tool in Uganda. There are two phases to the research project. Phase 1 - Tool Adaptation (Nearly Completed) During Phase 1, we aimed to validate the usage of the Freedom Greenlight tool in Uganda. Key Willow personnel and survivors participated in a workshop with these guiding questions: 1. Which word choices, images, and indicators from the global Freedom Greenlight are culturally recognizable and contextually relevant? Which need to be adapted for relevance to the Uganda context, and in what way? 2. Which locally relevant indicators should be added to the tool when it is used by Willow’s Uganda-based aftercare program? All adaptations are reviewed by research personnel, experts in the Greenlight methodology, and a clinical psychologist. The adaptations will be incorporated into the tool before Phase 2 begins. Phase 2 - Pilot Freedom Greenlight (Duration: Enroll participants for six months beginning in November/December 2022; collect endline data through November 2023) We will pilot the tool, using random assignment of participants in order to evaluate the effectiveness of using the Freedom Greenlight case management tool compared to current standards of care. We are interested in learning how the Freedom Greenlight process impacts well-being, economic outcomes, and reintegration outcomes. Interviews will be conducted to further understand case managers’ and participants’ experiences with the Freedom Greenlight,1. Adapting and Piloting a Survivor-Led Case Management Tool (“Freedom Greenlight”),
USA 2023-07-27 21:01:23 2026-07-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sarah Juster
ID: UNCST-2023-R007855
Tree-Based Interventions in the Imvepi Refugee Settlement in Uganda
REFNo: NS544ES

Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from staff of UNCHR, OPM through additional interviews and attending settlement Refugee Welfare Council and Local Council meetings,Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from staff of UNCHR, OPM through additional interviews and attending settlement Environment and Livelihood sector meetings,Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from Refugee Welfare Council and Local Council members,Gain overarching context for Tree-Based Intervention implementation in Imvepi ,Specifically code transcripts to synthesize themes related to NGO staff perspectives on the challenges of Tree-Based Intervention implementation and recommended programming adjustments,Employ content-analysis coding and axial coding of transcripts of staff interviews and organizational documents for qualitative synthesis of organizational activities and characteristics,Use a comparative table to specifically assess patterns in terms of overlap between Tree-Based Intervention activities and characteristics of the promoting NGO,Synthesize the characteristics and activities of four NGOs promoting Tree-Based Interventions in Imvepi,Compare the environmental characteristics of Tree-Based Interventions across four NGOs in Imvepi, including species choice and integration of TBI activities with local ecological features,Compare social dimensions of Tree-Based Interventions across four NGOs in Imvepi, including the integration of local perspectives and staff, focus on socioeconomic benefits of trees to participants, and inclusion of women as staff and program participants,Compare the nature, source, and duration of Tree-Based Intervention funding across four NGOs in Imvepi,Compare Tree-Based Intervention characteristics across four NGOs in the Imvepi refugee settlement,Identify which specific tree-based intervention activities (in the categories of conserving, planting, and facilitated re-sprouting trees) each of four NGOs in Imvepi are engaged with,Compare Tree-Based Intervention activities among four non-governmental organizations in the Imvepi refugee settlement,
USA 2023-05-04 16:39:21 2026-05-04 Natural Sciences Non-Clinical Trial Degree Award
Thomas McHale
ID: UNCST-2022-R008812
Optimizing the Dose of Flucytosine for Cryptococcal Meningitis
REFNo: HS2940ES

Determine if 50 mg/kg/day of 5-FC has a similar mortality benefit compared to 100 mg/kg/day,Reduce the cost and supply burden of treating an individual with cryptococcal meningitis,Determine if 50 mg/kg/day of 5-FC is a safer dosage compared to 100 mg/kg/day of 5-FC,Determine if 50 mg/kg/day of 5-FC is has a similar rate of cryptococcal clearance from CSF compared to 100 mg/kg/day,Determine the optimal dose of 5-FC for for management of induction phase of therapy for cryptococcal meningitis,
USA 2023-07-05 11:41:24 2026-07-05 Medical and Health Sciences Clinical Trial Degree Award
Christopher Daly
ID:
An Assessment of Maternal Recognition of Neonatal Sepsis following Implementation of Standardized Newborn Discharge Education in Western Uganda
REFNo: HS2902ES

The primary objective of this study is to identify whether implementing a newborn discharge education checklist and providing an educational module in the maternity ward setting will lead to improvement in mothers’ ability to identify the danger signs of neonatal illness. Secondary objectives will include identifying maternal barriers to education, identifying maternal opinions on educational needs, and identifying how mothers will seek care in case of neonatal sepsis concerns.
USA 2023-07-06 17:17:42 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janelle Wagnild
ID:
Evaluation of risk communication campaigns and development of a practical handbook for member states
REFNo: SS1825ES

To conduct a systematic evaluation of the reach and impact of national risk communication campaigns in four African countries (Ghana, Nigeria, Sierra Leone and Uganda) on SF medical products, paying careful attention to possible differences by socioeconomic group, urban/rural settings, region, age and gender. Drawing on the evaluation findings, to develop an evidence-based practical handbook for WHO Member States (globally) on strengthening risk communication on SF medical products, sharing best practice and ensuring feasibility for use in resource-constrained contexts.
USA 2023-07-27 20:56:49 2026-07-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
SOMACHI KACHIKWU
ID:
Designing Effective Online Professional Development for Teachers in Rural Schools: Evidence from a community primary school in Rural Uganda
REFNo: SS1826ES

The purpose of this qualitative research is to investigate how technology can be utilized to improve access to online professional development in rural schools. The intention is to capture the teacher's perceptions as it is relevant to designing practical and sustainable solutions. Gaining insight into how existing online professional development impacts teacher efficacy will highlight the highs, lows, and existing gaps that need to be addressed to strengthen teaching and learning in rural communities.
USA 2023-10-10 15:41:57 2026-10-10 Social Science and Humanities Non-Clinical Trial Degree Award
Monica Swahn H
ID: UNCST-2021-R012004
TOPOWA Cohort Study
REFNo: HS2959ES

Through a prospective cohort of AGYW, determine if SeSTT modifies the pathways between proximal social and environmental stressors and mental health outcomes, through the RDoC constructs of negative valence, sustained threat, and arousal and regulatory systems. We will measure threat reactivity in fear conditioning, ratio of salivary cortisol, dehydroepiandrosterone (DHEA) and α-amylase, validate drug and alcohol use through urinalysis, sleep quality and environmental stressors (Garmin Vivoactive 3 wearable sensors, 5 daily diaries).,
USA 2023-07-06 17:06:28 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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