Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Kalembe Justine
ID: UNCST-2025-R020881
 Financial Accountability and Organizational Performance of Public Sector Institutions in Uganda. A case of the Parliament of Uganda
REFNo: SS5411ES

i. To assess the relationship between financial accountability and budgetary control in the Parliament of Uganda. ii. To evaluate the effect of budget execution on the internal control systems in the Parliament of Uganda iii. To examine the mediating effect between internal control systems and organisational performance of the Parliament of Uganda. iv. To determine the Direct contribution of financial accountability to the organisational performance of the Parliament of Uganda.
Uganda 2026-07-09 18:44:42 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Platform Adaptive Randomised Trial for NEw and Repurposed Filovirus treatmentS
REFNo: HS7849ES

To evaluate the impact of potential treatments on mortality in patients with filovirus disease. ,
 Uganda 2026-06-08 21:31:41 2029-06-08 Medical and Health Sciences Clinical Trial Non-degree Award
Asiimwe Shane Ian
ID: UNCST-2024-R002876
 Postpartum urinary incontinence among mothers in Kampala, Uganda: Prevalence, factors associated, lived experiences and predictors of persistence of incontinence.
REFNo: HS7886ES

4. To explore other pelvic floor dysfunctions among women with postpartum urinary incontinence in Kampala, Uganda (Sub-study IV). ,2. To establish the prevalence and the predictors of persistence of postpartum urinary incontinence among women in Kampala, Uganda (Sub study II).,2. To describe the lived experiences of women with postpartum urinary incontinence in Kampala, Uganda (Sub study II),1. To determine the prevalence and factors associated with postpartum urinary incontinence among women in Kampala, Uganda (Sub study I) ,To determine prevalence and factors associated with postpartum urinary incontinence, describe the lived experiences of affected women and establish predictors of persistence of urinary incontinence among women who have had child birth in Kampala Uganda.,
 Uganda 2026-06-25 22:46:06 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to Monitor Grey Crowned Cranes in Uganda through Colour Band Ringing and Aerial Surveys
REFNo: NS1291ES

1. To establish a standardized crane ringing program by fitting ELSA colour rings on 20 Grey Crowned Crane chicks annually over a five-year period.
2. To track and document movement patterns and habitat use of colour-marked cranes across breeding, foraging, and dispersal landscapes.
3. To estimate survival rates and recruitment of juvenile cranes through periodic resighting of marked individuals.
4. To generate baseline biological and ecological data (including morphometrics) to address key knowledge gaps in the species’ life cycle.
5. To strengthen evidence-based conservation planning and adaptive management for Grey Crowned Crane populations in Uganda.
6. Provide data on Grey Crowned Crane populations and their distribution in Uganda
7. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
8. Identify areas where the potential exists for crane conservation interventions


Uganda 2026-07-09 19:34:31 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
Adalbert Aineomucunguzi
ID:
Understanding movements, behaviour, and habitat utilization of the Grey Crowned Crane in Uganda through Satellite Tracking
REFNo: NS1287ES

i. Identify core areas within the landscape utilized by cranes, determine their characteristics, explain why cranes prefer them, and assess their conservation status.
ii. Determine the timing of seasonal movements and the factors that influence them.
iii. Understand cross-border movements and their extent.
iv. Understand the home ranges of cranes during and after the breeding seasons.
v. Understand the annual survival rates of cranes and gain a better understanding of the causes of mortality.

 Uganda 2026-07-09 19:18:30 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
muyunga ashiraf
ID: UNCST-2025-R021888
 CUSTOMARY LAND DISPUTES ADJUDICATION AND TENURE SECURITY IN UGANDA: A CASE STUDY OF ACHOLI SUB REGION
REFNo: SS5467ES

a)To examine the legal and institutional framework governing customary land tenure adjudication in Uganda and its applicability to the Acholi context. b) To examine the jurisprudential approaches and evidentiary standards adopted by superior courts in the adjudication of customary land disputes in the Acholi sub-region. c) To assess the impact of formal judicial outcomes on tenure security within the plural adjudicatory context of the Acholi sub-region d) To propose legal and institutional reforms for strengthening the adjudication of customary land disputes and tenure security based on findings from the Acholi subregion.
 Uganda 2026-07-09 19:33:37 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Spleen carriage of the malaria parasite, immune responses and host-parasite interactions.
REFNo: HS7898ES

The overall aims of this project are to: 1) Comprehensively map and characterize the immune landscape during malaria in spleens from currently infected and exposed individuals. 2) Identify key processes driving malaria immune development and, identify and test novel therapeutic targets and vaccine platforms that can boost immune development during infection or vaccination 3) Identify the burden of Plasmodium falciparum hidden in the spleen and conduct parasite drug sensitivity testing, phenotyping, genotyping and transcriptomic analyses to compare parasites in the spleen versus those in peripheral blood
Uganda 2026-07-09 18:53:58 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick ALUKU
ID: UNCST-2026-R025007
 DETERMINANTS OF MARKET ACCESS FOR SMALLHOLDER HORTICULTURE FARMERS IN MBALE DISTRICT: A CASE STUDY OF ONION AND CARROT PRODUCERS IN WANALE SUB-COUNTY...
REFNo: A803ES

This study aims to examine the determinants of market access for smallholder horticulture farmers in Mbale district: a case study of onion and carrot producers in Wanale Sub-County. Specific objectives: The study aims to achieve the following objectives: 1. To assess the effect of market infrastructure on market access for smallholder horticulture farmers in Wanale Sub-county. 2. To examine the effect of institutional support on market access for smallholder horticulture farmers in Wanale Sub-county. 3. To determine the effect of transaction costs on market access for smallholder horticulture farmers in Wanale Sub-county. 4. To find out the other factors affecting market access for smallholder horticulture farmers in Wanale Sub-county.
 Uganda 2026-07-09 19:36:00 2029-07-09 Agricultural Sciences Non-Clinical Trial Degree Award
Betty Nyangoma
ID: UNCST-2025-R022905
 Gut Microbiome and Depression among People Living with HIV in Uganda
REFNo: HS7947ES

1: Characterize gut-microbiome composition and predicted functional pathways among 60 adults living with HIV (PLWH). 2: Evaluate whether gut microbiome composition and predicted functional pathways are associated with HIV-related factors (e.g., viral load, disease duration, and ART regimen) and depressive symptoms among Ugandan adults living with HIV in Kampala.
Uganda 2026-06-30 16:37:10 2029-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 POPULATION-BASED EVALUATION OF THE EPIDEMIOLOGY OF NON-COMMUNICABLE DISEASES AND SOCIOCULTURAL CONTEXT AMONG ADULTS OF TWO RURAL POPULATIONS IN UGANDA.
REFNo: HS7934ES

To build a cohort platform of adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda, with linkage to routinely collected clinical and/or medico-administrative data at the health centre to answer pertinent research questions about NCDs. ,To determine the trends in prevalence and incidence of Diabetes Mellitus and Hypertension among the cohort participants in among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,To document the sociocultural determinants of health to inform the development of community-led strategies for health promotion and improved quality of life among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda. ,To determine the burden of known risk factors such as obesity, lifestyle, smoking and diet, associated with Diabetes Mellitus and Hypertension among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,.To determine the prevalence of Diabetes Mellitus and Hypertension and examine associated sociocultural factors among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,
 Uganda 2026-07-09 19:26:55 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Adaptive Pan-Filovirus Therapeutics Platform Under the MEURI Framework
REFNo: HS7969ES

To systematically collect clinical and safety data to inform future therapeutic development and outbreak preparedness.,To provide monitored emergency access to investigational therapeutics for patients with filoviral disease during outbreaks.,
 Uganda 2026-06-23 16:25:48 2029-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayebare DavidSantison
ID: UNCST-2025-R023207
 POSTTRAUMATIC STRESS, SUICIDALITY AND SELF-HELP PLUS AMONG SELF-SETTLED YOUNG REFUGEES IN MBARARA CITY, SOUTHWESTERN UGANDA
REFNo: HS7984ES

1.4 Objectives 1.4.1 Broad Objective To evaluate the effect of the Self-Help Plus (SH+) on posttraumatic stress and suicidality in self-settled young refugees aged 15-24 in Mbarara City, southwestern Uganda. 1.4.2 Specific Objectives 1. To determine the prevalence of suicidality among self-settled young refugees aged 15–24 years in Mbarara City, southwestern Uganda. 2. To assess the severity of posttraumatic stress symptoms among self-settled young refugees aged 15–24 years in Mbarara City, southwestern Uganda. 3. To evaluate the effect of the Self-Help Plus (SH+) intervention on posttraumatic stress symptoms among self-settled young refugees aged 15–24 years in Mbarara City, southwestern Uganda. 4. To evaluate the effect of the Self-Help Plus (SH+) intervention on suicidality among self-settled young refugees aged 15–24 years in Mbarara City, southwestern Uganda.
Uganda 2026-06-29 14:49:40 2029-06-29 Medical and Health Sciences Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Development of a Rapid Fieldable Nanopore Sequencing-based Prognostic and Diagnostic Assay to Advance Clinical Management Decision-Making
REFNo: HS7987ES

- Verify harmonized sample preparation workflow from archived biospecimens for the integrated pathogen diagnostic and host-response assay that is run on the INSPIRE device - Verify functionality of integrated software and hardware required for the INSPIRE device on archived biospecimens
Uganda 2026-07-09 19:37:11 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred  Okuku Machyo
ID:
EVALUATING THE INTEGRATION OF PEGFILGRASTIM FOR THE MANAGEMENT OF CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS8034ES

1. To assess the feasibility and uptake of pegfilgrastim prophylaxis among eligible adult chemotherapy patients at UCI, including reach, fidelity, and vial utilization patterns.
2. To compare clinical outcomes, specifically FN incidence, infection-related hospitalizations, and chemotherapy dose delays or reductions, between pegfilgrastim recipients and historical cohorts managed without routine G-CSF prophylaxis.
3. To document baseline filgrastim prescribing patterns, dosing practices, and associated clinical outcomes prior to pegfilgrastim integration.
4. To evaluate healthcare workers’ knowledge, attitudes, and perceptions regarding FN prevention and the comparative use of pegfilgrastim versus filgrastim.
5. To identify system-level, provider-level, and process-level barriers and facilitators influencing pegfilgrastim implementation and long-term sustainability within UCI.

 Uganda 2026-07-09 19:40:59 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joan Busingye
ID: UNCST-2026-R026289
 COGNITIVE BEHAVIORAL INTERVENTIONS AND PATIENT RECOVERY AMONG INDIVIDUALS WITH MENTAL ILLNESS. A CASE OF SELECTED HOSPITALS IN CENTRAL UGANDA
REFNo: SS5507ES

1. To determine the influence of cognitive interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
2. To assess the effect of emotional interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
3. To examine the influence of behavioral interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
4. To evaluate the moderating effect of patient-related factors (age, gender, diagnosis, duration of illness, treatment adherence, and cultural beliefs) on the relationship between cognitive behavioral interventions and patient recovery in selected hospitals in Central Uganda.

 Uganda 2026-07-09 19:38:45 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Laureen Muhairwe Lumina Marie
ID: UNCST-2026-R026157
 PRICING, AVAILABILITY AND AFFORDABILITY OF BRAND AND GENERIC ESSENTIAL MEDICINES: EVIDENCE FROM UGANDA
REFNo: HS8018ES

Aim: To evaluate the pricing, availability, and affordability of brand/originator and generic essential medicines
across public, private, and NGO/mission pharmacy sectors in Uganda, and to identify barriers and facilitators
to generic substitution.
Specific Objectives:
• To determine price differences between originator and generic essential medicines across up to 8
pharmacy facilities in Uganda (public, private, NGO).
• To assess the availability of originator and generic medicines across facility types, expressed as a
percentage of medicines found in stock on the day of the survey.
• To calculate affordability of essential medicines using the days' wage methodology, expressed in days’
wages of the lowest paid government worker.
• To analyse how Uganda's NMP (2015) provisions on generic substitution are implemented in practice,
drawing on pharmacist and key stakeholder perspectives.
• To identify barriers and facilitators to generic medicine dispensing from pharmacist and key stakeholder
perspectives to inform targeted policy interventions.
• To provide evidence-based policy recommendations for Uganda’s Ministry of Health on pharmaceutical
pricing policy, generic substitution enforcement and access to essential medicine access.
 Uganda 2026-06-29 14:54:17 2029-06-29 Medical and Health Sciences Non-Clinical Trial Degree Award
ISMAH SERUNJOJI
ID: UNCST-2026-R023494
 ENTREPRENEURIAL ORIENTATION AND INNOVATION ECOSYSTEMS IN THE INDUSTRIAL SECTOR OF KAMPALA, UGANDA
REFNo: SS5386ES

1.To examine the effect of autonomy on the innovation ecosystems of the industrial sector of Kampala, Uganda. 2.To assess the effect of innovativeness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 3.To investigate the effect of risk-taking on the innovation ecosystems of the industrial sector of Kampala, Uganda. 4.To evaluate the effect of proactiveness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 5.To analyse the effect of competitive aggressiveness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 6.To investigate the effect of the moderating variables (Government, finance and infrastructure) on the innovation ecosystems of the industrial sector of Kampala, Uganda.
Ugandan 2026-07-09 18:50:21 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Kerry Holden Louise
ID:
The Promise of Science: Deliberating on health, biomedicine and democracy in the Ugandan parliament
REFNo: SS8ES

The proposed research seeks to examine whether, how and in what ways scientific capacity building in the Ugandan parliament and supporting offices and organisations improves political deliberation using health-related, biomedical and scientific knowledge.
UK 2016-07-01 2019-07-01 Social Science and Humanities Non-degree Award
Yolana Pringle
ID:
Violence and public health in East Africa, c.1950s-1980s
REFNo: SS9ES

This project represents the first historically-grounded analysis of the relationship between violence and public health in mid-twentieth century East Africa. It does so through three case studies, examining the impact of violence on the health of civilian populations and on public health responses during: Kenya’s Mau Mau rebellion (1952-9), the Rwenzururu movement in western Uganda (1960s and 1970s), and civil war in the Luwero Triangle (1982-6). The project will draw from archival material in Uganda’s National and District archives, the Kenya National Archives, and international organisations like the International Committee of the Red Cross (ICRC), UNICEF, and the World Health Organization (WHO).\r\n\r\nThe project's research objectives / questions are to determine:\r\n- To what extent did public health priorities shift during periods of collective and interpersonal violence?\r\n- How did public health officials and international organisations respond to problems of:\r\n - Infectious and communicable diseases\r\n - Water and sanitation\r\n - Nutritional diseases\r\n - Physical and psychological trauma\r\n - Access to healthcare\r\n- Who has been responsible for health during periods of collective and interpersonal violence?\r\n\r\nThrough these research questions, the project aims:\r\n- To broaden our understanding about the operation of public health in sub-Saharan Africa in the past\r\n- To shed new light on the dynamics of violence in East Africa since the 1950s\r\n- To extend our understanding of the emergence of violence as a global public health priority, and the role of East Africa within this\r\n\r\nA full research proposal is attached to this application.
 UK 2016-08-24 2019-08-24 Social Science and Humanities Degree Award
Jenny Farmer
ID:
The Global Methane Project; Monthly Observations, Yearly Assassments
REFNo: NS4ES

The aims of this project are to:\r\n1. achieve a significant improvement in the measurement of methane and to understand what changes are happening at global and regional scales.\r\n2. understand why these changes are occurring through targeted field campaigns and the analysis of atmospheric measurements using advanced modelling methods.\r\n3. predict how methane sources and sinks may change in future.\r\n
 UK 2017-03-17 2020-03-17 Natural Sciences Non-degree Award
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