Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sara Weschler Weschler
ID:
Deep Roots and Bitter Greens: Legacies of Colonial-Era Forced Displacement in Western Acholiland
REFNo: SS419ES

For my Master’s thesis research I studied the way British colonial officials used Sleeping Sickness control measures to justify the forced relocation of the entire population of western Acholiland between 1911 and 1920. For my PhD dissertation research, I will use qualitative interview methods to explore how the history of this early colonial-era forced displacement is remembered and understood in Acholiland today. I intend to examine what sorts of socio-cultural changes colonial-era displacement precipitated in Acholiland. At the same time, though, I hope to trace examples of cultural resilience and examine how Acholi culture and society recovered from these upheavals over the course of the intervening century.
USA 2020-02-19 2023-02-19 Social Science and Humanities Degree Award
Catherine Carlson
ID: UNCST-2023-R007222
Promoting Resilience for Survivors of Trafficking: Evaluating a Yoga-Based Approach in Kampala, Uganda
REFNo: SS420ES

Healing and Resilience through Yoga (Hart Yoga) is a trauma-informed yoga program to support survivors of human trafficking in Uganda with psycho-social recovery. The
proposed study will evaluate Hart Yoga’s feasibility, acceptability and impact with women and adolescent girls residing in Willow International’s (https://www.willowinternational.org/) shelters for survivors of human trafficking in Kampala, Uganda. This study will advance the limited field of health and mental health research with survivors of human trafficking and provide pilot data for publication and the development of a subsequent effectiveness trial. The methodology will address two primary objectives:

• Objective 1: To determine Hart Yoga’s feasibility and acceptability among participants and successful delivery within a residential shelter setting.
• Objective 2: To assess physical, psychological and social outcomes among program participants using qualitative and quantitative methods.

USA 2020-03-18 2023-03-18 Social Science and Humanities Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
Outcomes Following Surgical Release of Gluteal Fibrosis in Children of Eastern Uganda
REFNo: HS561ES

This study is a longitudinal case series to evaluate if surgical release of gluteal fibrosis in Ugandan children has a sustained benefit. We will examine the two-year outcomes after surgical release of gluteal fibrosis in children undergoing surgical intervention for gluteal fibrosis.

USA 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
Kristen Reid
ID:
COVID-19 in Uganda: Epidemiology and Treatment Outcomes of the First 75 Cases
REFNo: HS677ES

3. To describe both immediate and intermediate outcomes of the first 75 Covid-19 patients in Uganda up to 6 months post discharge.,2. To describe the course of illness and treatment of the first 75 cases of COVID-19.,1. To describe the characteristics and clinical manifestations of the first 75 consecutive cases of COVID-19 infection in Uganda.,
USA 2020-07-15 2023-07-15 Medical and Health Sciences Non-degree Award
Travis  Curtice Benjamin
ID:
Public Health, Trust, and Livelihoods: The Case of COVID19 in Uganda
REFNo: SS465ES

The key objectives of this study are to explore 1) how support for, and trust in state institutions shape individuals’ responses to public health crisis caused by the Coronavirus; and 2) more generally, the effect of COVID19 on income and livelihoods in a low-income country setting.

Overall Objectives
The coronavirus continues to spread across the globe. While there have been several early assessments of individuals' concerns and behavior in response to the shifting landscape of the pandemic, most work thus far has concentrated in OECD countries. We therefore know far too little about the impact of the Coronavirus on everyday life in low-income countries, where the virus has made a late entry. Focusing on the case of (rural) Uganda, our proposed study aims to close this gap. Results from this study will provide important insights into the relationship between trust in the government and public health and the impact of the public health crisis on migration, money transfers, and economic and food insecurity.

We propose to conduct a short phone survey that builds on a recently completed randomized control trial (RCT). The follow-up survey will allow us to test whether trust in political institutions are important not only in shaping individuals’ attitudes (e.g., their assessment of governments mitigating actions), but also their preventative health behaviors in response to the novel Coronavirus in Uganda. We are also interested in documenting how the Coronavirus is affecting the livelihood and wellbeing of the rural poor in a low-income country setting, where Covid-19 research has been sparse.

USA 2020-07-17 2023-07-17 Social Science and Humanities Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
KarenBeth Bohan Heikkinen
ID:
Assessment of Online Modules to Increase Knowledge of Geriatric Care in Health Care Professionals RefNo: MAKSHSREC-2020-6
REFNo: HS727ES

To determine the pharmacists’ satisfaction with pharmacy geriatric online training.,To determine the learning preference in terms of online compared to live educational sessions before and after using the online modules for professional development,To determine the retention of knowledge of geriatric care at three months after completion of all five online educational modules.,To assess the improvement of pharmacy professionals’ knowledge of geriatric care after participating in online educational modules.,
USA 2020-09-29 2023-09-29 Medical and Health Sciences Non-degree Award
Sona Shah
ID:
Adoption of a wireless vital sign monitor for observation of COVID-19 patients
REFNo: HS733ES

1. To evaluate the feasibility of a wireless vital sign monitor for use on critical patients in COVID-19 treatment facilities
2. To assess the accuracy of a wireless vital sign monitor (neoGuard) on adult patients
USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Dorit Stein Talia
ID: UNCST-2022-R010349
Policy Lessons from the COVID-19 Response in Uganda: Exploring Subnational Variation in the Maintenance of Essential Health Services for Women and Children
REFNo: SS1386ES

1. Measure and assess variation in district-level implementation of national guidelines to maintain delivery of essential health services in the context of COVID-19 across key health systems functions
2. Assess whether implementation of guidelines explains variation in performance for maintaining essential RMNCH services during the first year of the pandemic
3. Develop policy recommendations to improve governance of essential service delivery during emergencies

USA 2022-08-12 13:58:11 2025-08-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nathan Fiala
ID: UNCST-2022-R009060
The Long-term Impacts of a cash-based Employment Program in Northern Uganda
REFNo: SS501ES

1.To evaluate the long-term effectiveness of a cash-based youth employment program using a randomized controlled trial.
2. To understand the effect of COVID-19 and restrictions on youth employment
USA 2020-09-16 2023-09-16 Social Science and Humanities Non-degree Award
Matthew Bird Aileen
ID:
Consumer Protection Survey
REFNo: SS523ES

In this study, we aim to generate insights on consumer protection topics related to mobile telecommunications and digital finance in Uganda. Areas to be explored through this nation-wide phone survey include consumer usage and preferences regarding service providers, levels of trust, pricing awareness, challenges, fraud, dispute resolution, and the impact of COVID-19 on these topics. This project is being conducted in partnership with the Uganda Communications Commissions (UCC).
USA 2020-08-10 2023-08-10 Social Science and Humanities Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Assessing Health Professionals’ Knowledge, Perspectives and Practices Regarding HPV and Cervical Cancer Prevention and Control among Women Living with Human Immunodeficiency Virus Infection in Uganda
REFNo: HS782ES

General Objective The proposed study seeks to examine the role that health professionals play in influencing WHIVs’ perceptions of HPV and cervical cancer and their associated health behaviors in Uganda.

Specific Objective
Interview public health and health care professionals (including clinicians, nurses, counselors, other/public health professionals, and community health workers/village health teams) to examine the following:
1. Knowledge regarding how HPV or cervical cancer impacts WHIV, which populations are impacted most, and frequency of HPV vaccination, screening and treatment. 2. Perspectives regarding barriers/facilitators of cervical cancer and HPV prevention and treatment among WHIV. 3. Practices regarding HIV professionals’ work in cervical cancer and HPV.
USA 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Warren Phipps
ID:
Attitudes and Practices of Antimicrobial Resistance and Stewardship at the Uganda Cancer Institute
REFNo: HS871ES

We will investigate the knowledge, attitudes, and practices about antimicrobial use and antimicrobial resistance among the doctors (including medical officers, fellows, oncologists, and surgeons), nurses, and pharmacists at the Uganda Cancer Institute (UCI).

The aims of the study are;
Aim 1: To examine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial resistance.
Aim 2: To determine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial stewardship.
Aim 3: To understand perceived barriers to the diagnosis and management of infections in patients at UCI

USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Geospatial Analysis of Kampala Cancer Registry Data
REFNo: HS873ES

Objective 1: Identify spatial and spatiotemporal patterns of cancer in Uganda. a) Use geospatial mapping techniques to estimate cancer burdens across geographic space and through time. b) Create visual representations of cancer patterns (maps, graphs). Objective 2: Examine relationships between social and environmental factors and cancer outcomes in Uganda. a) Use statistical analysis techniques to determine associations between environmental factors and cancer outcomes. Objective 3: Pilot the collection of new KCR variables a) For each new case, we will attempt to acquire marital status, education level, occupation, religion, national Identification number (NIN) (new in Uganda), and precise geographic location information. Objective 4: Determine the true spatial extent of KCR data collection potential. a) Identify the number of cases that are discovered and excluded under current practice, as well as the individual’s parish of residence.
USA 2020-09-28 2023-09-28 Medical and Health Sciences Non-degree Award
Daniella CHUSYD Elyse
ID:
Anthropogenic related stress on reproduction in African forest elephants (Loxodonta africana cyclostis)
REFNo: NS137ES

(i) To determine how human activity influences elephant stress and reproduction.

(ii) To assess Elephants’ allostatic load (measure of the wear and tear on the body) in relation to proximity to humans.

(iii) To determine Elephants’ reproductive cycling status (is the elephant cycling or not) in relation to the elephant’s allostatic load.

USA 2021-07-30 2024-07-30 Natural Sciences Non-degree Award
Christina Bergey Marie
ID: UNCST-2020-R014338
Genetic survey of bloodborne pathogens and investigation of malaria response in sanctuary chimpanzees
REFNo: NS139ES

Our proposed study has three main objectives:

1. To determine which blood-borne pathogens sanctuary chimpanzees carry, with a particular interest in those which can be transmitted from human to chimpanzee (anthroponoses) and vice versa (zoonoses);

2. To diagnose malaria infection in sanctuary chimpanzees and determine which malaria parasite species are present, with a particular interest in human malaria that may be infecting the chimpanzees; and

3. To describe the genetic mechanisms underlying the chimpanzee immune system response to malaria, and contrast this with that of humans.
USA 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Matthew  Cotten Louis
ID:
Local sequencing of SARS-CoV-2 from Uganda COVID-19 cases
REFNo: HS936ES

To document the transmission dynamics of COVID-19 in Uganda using full viral genome sequencing
USA 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Anthony  Fuller
ID:
Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2000â„¢) in Detecting Subdural and Epidural Hematomas in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS1010ES

Aim 1: Determine whether the InfraScanner 2000â„¢ detects epidural and/or subdural hematomas with adequate precision relative to CT scans to be used as a diagnostic tool for epidural and/or subdural hematomas.

Aim 2: Use these findings to inform the feasibility of conducting a future trial in which the InfraScanner 2000â„¢ is used as a stand-alone diagnostic tool for intracranial hematomas, and therein, to determine candidacy for decompressive craniotomies in patients who suffer TBIs in places where CT scans are not available.
USA 2021-07-13 2024-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kristie McComb
ID:
Evaluation of the Patient Navigation Program at Uganda Cancer Institute
REFNo: HS1014ES

The goal of this study is to document the experiences and lessons learned (through a baseline and endline process evaluation), and the ways in which this program improved outcomes for cancer patients (through an outcome evaluation). These evaluations will document best practices for other countries considering similar projects, provide programmatic evidence on the usability and effectiveness of the program development methodology, and guide development of a resource toolkit for other health institutions like UCI seeking to start a patient navigation program.

The evaluation questions are:

Process Evaluation (2020 and 2021)
1. Coordination and Referral: Has the patient navigation program increased coordination/ referral of patients within Uganda Cancer Institute (UCI) and with other support services (e.g. Civil Society Organizations (CSO), psychosocial services and other necessary services)?
2. Fidelity and Adaptation: To what extent is the patient navigation program implemented as intended and what changes to the program have been made over time?
3. Improving Understanding of Care: To what extent does the patient navigation program reduce barriers to understanding cancer diagnosis and accessing treatment services and how does patient navigation increase adherence to patient treatment plans?
4. Training and Technical Assistance: How effective is the training and technical assistance provided by American Cancer Society (ACS) in supporting new patient navigation program design, preparation and implementation?
5. Sustainability: How prepared is the program to transition to UCI ownership?

Outcome Evaluation (2023)
1. To what extent, if at all, are the program activities focused on addressing the needs of the target population?
2. To what extent do decision makers and other stakeholders view patient navigation as the right intervention to address challenges to patient access to cancer treatment?
3. How effective is the patient navigation program at improving hospital processes and service delivery?
4. How effective is the patient navigation program at improving desired outcomes at the individual patient and caregiver level?
5. How effective is the training and technical assistance provided by ACS in supporting new patient navigation program design, preparation and implementation?
6. To what extent is the patient navigator program likely to continue after ACS support ends?

USA 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
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