Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Katia  Peterson
ID:
A quasi-experimental study of Interpersonal Group Therapy (IPT) treatment attribution on decreasing depression severity among depressed women in Iganga District, Makuutu Sub County and Mukono District, Kimenyedde Sub Counties
REFNo: SS297ES

General objective

To establish a baseline prevalence of depression and determine the period and treatment effects of depression severity between depressed women in Iganga (Makuutu Sub County) and Mukono District (Kimenyedde Sub Counties).

Specific objectives
1. Determine the prevalence of depression in Makuutu Sub County (Iganga) and Kimenyedde Sub Counties (Mukono).
2. Determine the change in depression severity, as measured by the PHQ-9, within control subjects at six months and one year follow up.
3. Determine the change in depression severity, as measured by the PHQ-9, between control and treatment subjects at six months and one-year follow up.
4. Determine the change in well-being as measured by the “Well-being Indicator Survey” within control subjects and between control and treatment subjects at six months and one year follow up.

USA 2019-05-07 2022-05-07 Social Science and Humanities Non-degree Award
PETER SPENCER SIMNER
ID:
Etiology of Nodding Syndrome: an Epileptic Disorder of East African Children
REFNo: HS410ES

Increase understanding of the role of environmental exposures, notably to specific neurotropic viruses, as risk factors for Nodding syndrome.
USA 2019-12-04 2022-12-04 Medical and Health Sciences Non-degree Award
Mackenzie Carlson
ID:
Investigating the prevalence and practices of herbal medicine use in antenatal care in Mukono District, Uganda
REFNo: HS386ES

Specific Aim 1: Collect qualitative data using a standardized questionnaire to evaluate the prevalence of herbal medicine use in pregnancy, including which herbs are taken for what purposes.
Specific Aim 2: Identify ways in which herbal medicines are obtained and prepared for use in pregnancy.
Specific Aim 3: Identify the concordance between what recommendations and medications are given to pregnant women to prepare for labor and delivery by traditional birth attendants versus government midwives.
Hypotheses: We hypothesize that most pregnant women in the Mukono District use herbal medicine during pregnancy and that the exact preparations of herbal medications vary by traditional birth attendant preparing them and by village.
USA 2019-06-24 2022-06-24 Medical and Health Sciences Non-degree Award
Christa Kuntzelman Marie
ID:
Refugee Perceptions of their Rights in Uganda
REFNo: SS305ES

The purpose of this study is to learn (a) learn what rights refugees believe they have in Uganda; (b) learn how refugees understand the roles and responsibilities of the Ugandan Government, UNHCR, InterAid, and other NGOs (non-governmental organizations) to provide for refugees in the cities and in the settlements, (c) gain understanding of to whom refugees turn when they need assistance, and (d) understand the role of refugee-led organizations to support other refugees for learning rights or gaining assistance.
USA 2019-08-20 2022-08-20 Social Science and Humanities Degree Award
Dorsa Amir
ID:
Decision-making across cultures
REFNo: SS308ES

The aim of this study is to understand how children learn to make virtuous decisions – that making the right decision-- about resources and how children learn to invest cost and effort in resources that benefit the public community. We plan to determine how these behaviors develop and change with age and how they influence cooperation in children all over the world.
USA 2019-10-31 2022-10-31 Social Science and Humanities Non-degree Award
Jennifer Davis
ID: UNCST-2019-R000218
Reliable handpumps at scale? Evaluating costs and benefits of, and demand for, professionalized preventative maintenance services in rural Uganda
REFNo: SS309ES

(1) Characterize common models of infrastructure maintenance for rural boreholes with handpumps in Uganda.
(2) Assess rural communities’ willingness and ability to pay for professionalized preventative maintenance service designed to enhance handpump reliability.
(3) Estimate the costs and benefits of providing handpump maintenance services to communities in Apac and Kwania districts
USA 2019-06-24 2022-06-24 Social Science and Humanities Degree Award
Matthew Henderson George
ID:
Chimpanzee communication and its function in the regulation of fission-fusion social dynamics
REFNo: NS92ES

- Enhance overall understanding of gestural and vocal communication of East Africa Chimpanzees with a focus on the understudied female sex
- Understand how female chimpanzees use short-distance gestures with their infants and long-distance vocalizations to maintain fission-fusion dynamics
- Which gestural or postural markers are used by females and their infants specifically before joint travel
- What behavioural cues produced by infants and mothers differ prior to successful joint travel of all forms
-How behavioral context affects the pant-hoot structure in female chimpanzees
- How individual life-characteristics differences affect pant-hoot vocalizations
USA 2019-08-06 2022-08-06 Natural Sciences Degree Award
Kevin Hunt Dean
ID:
DRY HABITAT CHIMPANZEE ECOLOGY: IMPLICATIONS FOR HUMAN EVOLUTION
REFNo: NS101ES

Document feeding, social and locomotor behavior using 1-minute focal observations. Record food items, ranging behavior, canopy use, feeding rate and habitat use. Collect hairs for trace element analysis. Collect skeletal material from any deceased individuals. Analyze skeletal material for distinctive characteristics. Analyse hormone profiles to determine if lower levels of aggression are due to low T levels. Look for poisons in Muguri River to find source of sex organ abnormalities. Examine dental micro wear and trace elements in hair to determine diet. Look at genetic variations
USA 2019-09-05 2022-09-05 Natural Sciences Non-degree Award
Heather Brown
ID:
Evaluating the Impact of a Layperson EMS System on Morbidity and Mortality of Injured Patients in Masindi, Uganda
REFNo: HS414ES

The purpose of this study is to evaluate the effectiveness of a pilot layperson EMS system for commercial boda drivers and the feasibility of using a pre-existing trauma registry to evaluate the outcomes of these patients.

Primary Objective:

Evaluate the impact of a boda driver EMS system on time to presentation for ill and injured patients.

Secondary Objectives:

1. Evaluate the purpose and rate of utilization for a lay person EMS system in Masindi, Uganda.

2. Evaluate the impact of a lay person EMS system on patient morbidity and mortality at MKMC.

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Sona Shah
ID:
Validation of the safety and performance of a clinical vital signs monitor on infants and neonates: A pilot study
REFNo: HS420ES

1. To assess the safety of the Neopenda wearable vital signs monitor (neoGuard) in healthy infants (aged 8 to 16 weeks) and stable neonates (aged 0-28 days)
2. To determine the performance accuracy of neoGuard device in comparison to a gold standard monitor comparable to the Edan M3A Vital Signs Monitor

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Paula Rabaey Ann
ID:
A seat for every child: Ensuring safe and dignified mealtimes for children with disabilities
REFNo: SS1247ES

Determine in country stakeholder interest in promoting and using the chair,Determine percent change in caregiver stress level while feeding child in the chair versus current position (without adaptive equipment),Determine ability and level of ease/difficulty with which caregivers can independently position their child correctly in the chair ,Determine change in feeding position and tolerance for using the chair (from child’s current feeding position to being fed in the chair),To pilot test SPOON Foundation’s low-cost feeding chair for acceptability, usability, and feasibility for families with a child with a disability (CWD) in Uganda. ,
USA 2022-04-20 2025-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wyatt Brooks James
ID:
Community Lending and Outside Capital (CLOC)
REFNo: SS339ES

To measure the impact of community lending and outside capital on SILC members’ returns and default rate behavior, levels of liquid savings, and change in livelihood.
USA 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
Shana Warren
ID:
Vitamin A Supplementation (VAS) Post Event Coverage Survey (PECS) in Uganda
REFNo: SS1261ES

To conduct a PEC survey for the October-November 2021 round of the ICHD in Uganda,
USA 2022-04-21 2025-04-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Thornton
ID:
Solid Foundations and the Transition to Post-Primary School
REFNo: SS359ES

This proposed study will: 1. extend a longitudinal dataset of students who were participants in a randomised literacy intervention during grades 1-4, as they transition out of primary school and into their adolescence years; 2. measure the effects of foundational literacy skills in primary school – due to the intervention – on primary school completion, secondary school enrolment, and learning outcomes (also measure labor market participation, aspirations, motivation, and other measures of well-being); 3. compare the differential effects of two versions of delivery of the literacy program (a full-cost version and a lower-cost version) to estimate the differences in cost- effectiveness; and 4. compare two levels of exposure to the program (one year vs. four years) to estimate the differences in cost-effectiveness. The project will follow 5,348 students in two cohorts to grades 6/7.
USA 2022-01-07 2025-01-07 Social Science and Humanities Non-degree Award
Sarah Lofgren
ID: UNCST-2019-R001647
The Growth Study- Group Therapy In HIV For Depression In Uganda
REFNo: HS493ES

Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
USA 2019-12-09 2022-12-09 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
STUDY OF WASH AND ANTIMICROBIAL RESISTANCE IN UGANDA (SWAR-U)
REFNo: HS489ES

Primary objective: To describe the transmission dynamics and ecological niches of ESBL-E and ESBL-K within selected households from Kampala and Hoima

Secondary objectives:
To evaluate the drivers of Water, Sanitation, and Hygiene (WASH) practices and their relation to the faecal-oral transmission of extended spectrum beta-lactamase producing Eschericia coli and Klebsiella pneumoniae

To create a dynamic agent-based model to evaluate the drivers of antimicrobial resistance transmission in Uganda, through the incorporation of microbiological resistance data (ESBL-E and ESBL-K) and WASH observational data obtained from all households included in the SWAR-U study

USA 2019-12-13 2022-12-13 Medical and Health Sciences Non-degree Award
Aala Abdelgadir
ID:
Mosque Mapping Survey
REFNo: SS385ES

Religious institutions play an important role in the daily lives of Ugandans, as in other African countries. Yet, we understand little about the influence of religious institutions on social and political outcomes. This project focuses on the sway of Muslim religious institutions in shaping the opinions and behaviors of congregants. Specifically, we will study how mosques communicate with congregants, what types of messages they deliver, and how messages shape the attitudes and behaviors of congregants.

The research objectives of this project are to:
• Examine variation in sermons, including topics, religious citations, and tone.
• Assess how mosque and imam characteristics influence the nature of sermons.
• Explore how sermons shape congregant religious, social, and political attitudes and behaviors.

USA 2020-03-12 2023-03-12 Social Science and Humanities Degree Award
Robert Wyrod
ID:
Opportunity in a New Era of Development
REFNo: SS388ES

Conduct research on the growing relationship between China and Uganda in the area of development. Understand the new opportunities for improving economic growth in Uganda through a growing relationship with China as a valuable new development partner.
USA 2023-01-20 14:20:54 2026-01-20 Social Science and Humanities Non-degree Award
Amy Young
ID:
Causes of under-five child mortality in the slum communities of Kampala, Uganda: A Verbal and Social Autopsy Study
REFNo: HS507ES

The study seeks to identify the biomedical causes of death as well as the sociodemographic, behavioral and environmental factors associated with child mortality in the slum communities of Kampala. This includes recognition of illness, decisions around care-seeking, and care-seeking behaviors.
USA 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
THE AFRICAN RESEARCH COLLABORATION ON SEPSIS IN UGANDA (ARCS-UGANDA) COHORT STUDY: AN OBSERVATIONAL STUDY TO IMPROVE UNDERSTANDING OF SEPSIS EPIDEMIOLOGY, DEFINITIONS, HOST IMMUNE RESPONSE AND COSTS OF HOSPITAL CARE IN UGANDAN ADULTS
REFNo: HS511ES

General Objective:
To describe adult sepsis prevalence and incidence, validate sepsis definitions, characterize AMR, describe short- and long- term morbidity and mortality, identify host response to sepsis and quantify hospital costs using a cohort of adult patients with suspected sepsis admitted to hospitals in Uganda

Specific objectives:
1. Determine the epidemiologic characteristics, AMR characteristics, clinical outcomes (including morbidity, mortality and frequency of readmission after discharge from the hospital) and attributable costs from suspected sepsis in Ugandan hospitals
2. Evaluate performance characteristics of extant sepsis definitions/criteria when applied to a cohort of adult patients who fulfil study eligibility criteria for sepsis in Uganda
3. Characterize pathways of sepsis pathogenesis through exemplar pro-inflammatory (through neutrophil respiratory burst activity) and immunosuppressive (through HLA-DR) markers and agnostic transcriptomic analysis in a Ugandan sepsis cohort with a high prevalence of HIV infection.

USA 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
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