Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ALLAN BAGUMA
ID: UNCST-2021-R012022
Effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV KCCA health facility in Kampala.
REFNo: HS1879ES

General Objective
To determine the effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV health facility in Kampala.
Specific Objectives
1. To determine the pre-lockdown childhood immunization coverage at Kisenyi health facility in Kampala.
2. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala during the national lockdown.
3. To assess the barriers and facilitators of childhood immunization at Kisenyi health centre IV facility in Kampala during the covid 19 pandemic.
4. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala post the national lockdown

Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Alex Abal
ID:
POINT OF CARE TESTING TO REDUCE OVERTREATMENT OF CHLAMYDIA AND GONORRHEA IN HIV-POSITIVE PATIENTS IN KUMI, UGANDA
REFNo: HS3157ES

To determine the prevalence of urogenital and anorectal infections other than CT/NG in patients presenting to the ART clinic: Trichomonas vaginalis, herpes simplex virus-1 and 2, CT biovars L1, L2, and L3 causing lymphogranuloma venereum (LGV), mpx (monkeypox), and Mycoplasma genitalium.,to determine if adding a CT/NG POCT to the standard of care in the ART clinic reduces overtreatment of CT/NG in symptomatic patients.,To reduce overtreatment of CT and NG in HIV-infected individuals with STI complaints presenting to the ART clinic in Kumi hospital and to determine the prevalence of urogenital and anorectal infections.,
Uganda 2023-11-16 13:49:07 2026-11-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Apolo Balyegisawa P
ID: UNCST-2025-R017645
Evaluation of the XF 300 Flow Cytometer, CD4 easy count kit, CD4% easy count kit and CD4/CD8 easy count kit in Tests 1112 - Explorative External Method Comparison Study and 1149.2 - Clinical Performance Study
REFNo: HS6435ES

Test 1112 - Compare the results from the XF-300 Flow Cytometer and its reagent kits with the comparator device (FACSLyric) and reagent kits Test 1149.2 - Investigate the clinical performance of the XF-300 Flow Cytometer in combination with the three kits CD4, CD4% and CD4/CD8 easy count kit.
Uganda 2025-09-30 14:39:06 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mahsa Abassi
ID:
Utilization of SMS Messaging Services to Improve Retention in Care of HIV-Infected Individuals in Uganda Short Title: SMS-2-Retain (S2R)
REFNo: SS62ES

The objective of the study is to determine if mobile health (mHealth) technology (text/voice-messaging services) is an effective method of improving retention in care for newly diagnosed HIV-infected individuals enrolling into care, as compared to standard of care. This is a pilot, non-blinded, randomized trial of mobile health implementation into routine HIV care. This pilot trial will be focusing on 1) two-week retention in care of all HIV-infected participants from enrollment and followed by 2) participants who have been found to have cryptococcal antigenemia, a population of participants most at risk for early morbidity and mortality.
USA 2017-03-07 2020-03-07 Social Science and Humanities Non-degree Award
Abbey Kato
ID:
Child art: a meaning-making mechanism for children about their gender[ed] experiences and perceptions
REFNo: SS2341ES

To interrogate children’s visual art expression as a model for gender sensitization.,To examine the gender[ed] narratives that emerge from the child art experiences and perceptions expressed in the child art.,To explore children’s experiences and perceptions of their day to day life expressed through child art.,The main objective of the study is to explore how child art can be used as a meaning-making mechanism by children to express their everyday life gender[ed] experiences and perceptions.,
Uganda 2024-07-22 14:57:37 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
ABDUL WALUSANSA
ID:
Drug Resistant Bacterial Contamination and Efficacy of Selected Herbal Medicines Sold in Kampala, Uganda
REFNo: HS1278ES

The broader aim of this study is examining the prevalence, antibiotic susceptibility, resistance genes in bacterial contaminants, and the antibacterial efficacy of selected herbal medicines sold in Kampala, in order to contribute to the mitigation of AMR.,To determine the antibacterial efficacy of some herbal medicines against selected drug-resistant bacterial isolates in Kampala. ,To examine the risk factors for bacterial contamination of herbal medicines sold in Kampala, Uganda ,To determine antibiotic resistance genes in multi-drug resistant bacteria isolated from herbal medicines sold in Kampala.,To determine the prevalence and antibiotic susceptibility of pathogenic bacterial contaminants such as, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Salmonella spp, Shigella spp, and Clostridium perfringens in herbal medicines sold in Kampala.,
Uganda 2021-03-18 2024-03-18 Medical and Health Sciences Degree Award
Abel Nzabona
ID:
Institutional resilience and recovery from disasters and pandemics in selected districts of rural Uganda-exploring the implications for governance and public policy implementation
REFNo: SS2544ES

1. To provide a holistic picture of rural local government in the countries targeted by this project.
2. To provide an analysis of the resilience and sustainability of rural livelihoods.
3. To provide an analysis of governance processes and policy implementation systems for rural livelihoods in the two countries.

Uganda 2024-04-12 7:26:29 2027-04-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abel Atukwase
ID:
Assessment of Aflatoxin Exposure among Peri-urban Low Income populations in Kampala Capital City
REFNo: HS202ES

i.To assess the determinants of aflatoxin exposure among children (6-59 months) and mothers of reproductive age (15-49 years) ii.To estimate aflatoxin exposure among children (6-59 months) and mothers of reproductive age (15-49 years) iii.Assess the relationship between aflatoxin exposure an nutritional status of children (6-59 months) iv.To design and disseminate aflatoxin Information, Education and Communication materials for improving awareness on the effects of aflatoxins among the low income populations living in peri-urban areas of Kampala Capital City.
Uganda 2018-09-06 2021-09-06 Medical and Health Sciences Non-degree Award
Abel Atukwase
ID:
EXPOSURE ASSESSMENT AND ANALYSIS OF HEALTH RISKS ASSOCIATED WITH CONSUMPTION OF AFLATOXIN CONTAMINATED STAPLES IN UGANDA
REFNo: A132ES

The overall objective of the project is to generate information that will guide the development of evidence-based policies and strategies for management of health risks associated with aflatoxins in Uganda. The specific objectives are to;
1. Determine the levels of aflatoxins in maize, sorghum and groundnuts produced and consumed in Uganda
2. Assess aflatoxin exposure among children (6-59 months) and women of reproductive age (15-49 years)
3. Characterise the health risks associated with consumption of maize, sorghum and groundnuts among children 6-59 months and women of reproductive age (15-49 years)
4. Develop policy briefs aimed at improving awareness amongst policy makers and stimulate formulation of policies and strategies for mitigating aflatoxin associated health risks.
Uganda 2021-08-11 2024-08-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
The immune response to malaria within the germinal center
REFNo: HS2717ES

Comprehensively map the germinal center immune landscape during malaria infection.

Identify key cells and processes required for and/or disrupting the induction of malaria germinal center and antibody responses.

Identify key cells and processes required for germinal center and antibody induction to vaccines that are disrupted by malaria.

Identify and test drugs that can boost germinal center responses appropriate for use in malaria exposed children.

Uganda 2023-04-26 11:08:15 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5638ES

To estimate the site-specific IR of P. falciparum infection by rapid diagnostic test (RDT) testing, overall and by age group (5-11 years, 12-17 years, 18-60 years) during the active detection of infection period.
Uganda 2025-03-19 12:57:39 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Development of context-appropriate approaches for the recruitment and retention of women of childbearing age and pregnant women in antimalarial clinical trials
REFNo: HS6036ES

1. To understand the context, socio-cultural practices and beliefs around early pregnancy as well as collecting experience with and/or perception of previous clinical trials to inform the development of culturally acceptable and understandable communication materials about the SAFIRE trial, including the information sheets for obtaining consent.
2. To identify factors and individuals that may influence WOCBA and pregnant women’s decision-making around participation and retention in the clinical trial to be addressed as part of project procedures and communications.
3. To explore approaches for facilitating the inclusion of WOCBA and pregnant women (in early pregnancy) in the clinical trial, based on the findings from objective 2.
4. To identify key stakeholders (including household decision-makers, community leaders and opinion shapers, health sector actors), from community to national levels, to be included and involved in the community engagement strategy prior to trial implementation.

Uganda 2025-06-20 9:25:32 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Dihydroartemisinin-piperaquine plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone for the prevention of febrile illnesses in children with sickle cell anemia: a double-blind randomized controlled trial
REFNo: HS6294ES

1.
To compare the incidence of all-cause febrile illness among children with sickle cell anemia randomized to receive monthly SP vs. monthly DP+SP.
2.
To compare the incidence of adverse events among children with sickle cell anemia randomised to receive monthly SP vs. monthly DP+SP.
3.
To compare the prevalence of markers of antimalarial resistance, including those associated with SP and DP resistance, among parasitemic children with sickle cell anemia randomized to receive monthly SP vs. monthly DP+SP.
Uganda 2025-10-29 15:55:44 2028-10-29 Medical and Health Sciences Clinical Trial Non-degree Award
Patrick Mawadri
ID:
EFFECT OF ESTRUS SYNCHRONIZATION PROTOCOLS ON REPRODUCTIVE PERFORMANCE OF INDIGENOUS CATTLE ON EXTENSIVE MANAGEMENT SYSTEM IN UGANDA
REFNo: A219ES

i. To evaluate the conception rate of estrus synchronization protocols used in cattle on extensive management system in Uganda using retrospective data
ii. To compare the effects of modified ovsynch protocols on ovulation of cows of short horn zebu and Ankole long-horned cattle on extensive management system in Aswa Ranch in Northern Uganda
iii. To compare the effects of modified ovsynch protocols on conception of cows of short horn zebu and Ankole long-horned cattle on extensive management system in Aswa Ranch in Northern Uganda

Uganda 2022-09-20 12:54:54 2025-09-20 Agricultural Sciences Non-Clinical Trial Degree Award
Gladys Ayot Florence
ID:
Exploring Experiences of Domestic Violence for Female Teachers in Secondary Schools in Uganda
REFNo: SS1273ES

4. Explore the support mechanism available to female teachers affected by domestic violence.,3. Provide a description of female teachers’ reports on how staff affected by domestic violence negotiates through the challenges of domestic violence in performing their duties.,2. Assess the female teachers’ perspectives about the impact of domestic violence on the administrative roles of teachers.,1. Assess from the female teachers’ perspective how domestic violence affects teachers’ teaching function/roles.,The purpose of this study is to explore the experiences of female teachers affected by domestic violence, describe how domestic violence affects the professional roles of a teacher of secondary schools and to establish how administrators manage the situation for affected staff in schools in northern Uganda.,
Uganda 2022-04-22 2025-04-22 Social Science and Humanities Non-Clinical Trial Degree Award
SUNDAY ABIDRABO
ID:
SELF-CORRECTION STRATEGY EFFECTIVENESS IN IMPROVING PRIMARY SCHOOL LEARNERS’ MATHEMATICS ACHIEVEMENT. A CASE IN KOBOKO DISTRICT.
REFNo: SS2005ES

Main Objective:
To determine the effectiveness of the self-correction strategy in improving primary school learners' mathematics achievement.
Subsidiary Objectives:
To examine the influence of the self-correction strategy on primary school learners' problem-solving skills in mathematics.
To examine the influence of the self-correction strategy on primary school learners' metacognitive abilities in mathematics.
To identify any potential challenges in implementing the self-correction strategy in primary school mathematics education.
To provide strategies regarding the implementation of the self-correction strategy in primary school mathematics instruction.

Uganda 2023-11-20 15:24:56 2026-11-20 Social Science and Humanities Non-Clinical Trial Degree Award
Milcah Abasabyona
ID:
Intimacies of Identification and Lived Citizenship among the Ghetto Youths in Kampala, Uganda
REFNo: SS1654ES

Main Objective:
To investigate how citizen certification and identification influences levels of belonging to a place and space, impacts on citizen-state relationship and individual personhood.
Specific Objectives:
1. To capture the individual practical experiences of legal certification and identification processes among the Ghetto youths.
2. To examine the regulatory effects of identification documents on citizenship rights, a sense of belonging, and personhood among the Ghetto youths in Kampala.
3. To explore the different key Identification documents and their role in the day to day lives of the Ghetto Youths.
4. To trace the ways in which the undocumented Ghetto youths create alternative routes to lived citizenship and self-certification.
Uganda 2023-04-04 9:32:41 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Abner Baryaija Besigye
ID:
DECENTRALIZATION AND QUALITY PUBLIC HEALTHCARE SERVICE DELIVERY IN THE LOCAL GOVERNMENTS OF UGANDA: A CASE STUDY OF GREATER BUSHENYI DISTRICTS
REFNo: SS2347ES

(iv) To explore the stakeholders’ perception about the effectiveness and efficiency of quality public healthcare service delivery in Greater Bushenyi districts.,To assess the influence of political decentralization on quality public healthcare service delivery in Greater Bushenyi districts.,(ii) To assess association between administrative decentralization and quality public healthcare service delivery in Greater Bushenyi districts.,(i) To assess the effect of fiscal decentralization and the quality of public health care service delivery in the local governments of Greater Bushenyi districts.,The purpose of the study is to assess the relationship between the types of decentralization and the quality of public healthcare service delivery in the local governments of Uganda.,
Uganda 2024-06-21 18:14:03 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Adeline Boatin
ID: UNCST-2019-R001255
Wireless Physiologic Monitoring in Postpartum Women
REFNo: HS417ES

1. To estimate the clinical effectiveness of wireless physiologic monitoring of women in the first 24 hours after emergency cesarean delivery at Mbarara Regional Referral Hospital (MRRH)
2. To evaluate the clinical adoption of wireless physiologic monitoring at MRRH using an implementation science approach.
3. To use qualitative methods to explore clinical adoption and acceptability of wireless physiologic monitoring among postpartum women at MRRH and understand facilitators and barriers to uptake of wireless physiologic monitoring.
4. To estimate the cost of providing wireless physiologic monitoring of women in the first 24 hours after emergency cesarean delivery at MRRH
5. To estimate the incremental cost-effectiveness, measured as cost per severe maternal outcome adverted using wireless physiologic monitoring compared to current standard of care monitoring.

Ghana 2019-08-15 2022-08-15 Medical and Health Sciences Non-degree Award
Adeline Boatin
ID: UNCST-2019-R001255
Caesarean delivery in Uganda: a mixed methods study
REFNo: HS758ES

1. To use survey methods to explore practice patterns of clinicians around caesarean usage in Uganda.

2. To use qualitative methods to explore practice patterns of clinicians and clinical policy makers around caesarean usage in Uganda

3. To describe CS rates, factors associated with CS and maternal and neonatal outcomes according to Robson group classification at Regional Referral Hospitals and large private non-profit hospitals in Uganda

Ghana 2020-12-15 2023-12-15 Medical and Health Sciences Non-degree Award
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