Nsobya Samuel
ID: UNCST-2021-R012265
|
Characterizing artemisinin resistance in severe malaria (CHARISMA):
SMAART sub-study in Uganda
REFNo: HS3161ES
1. To characterize and compare the ex vivo drug susceptibilities of P. falciparum isolates from patients with and without severe malaria.
2. To characterize and compare genomic features of P. falciparum isolates infecting patients with and without severe malaria.
3. To assess whether presence of artemisinin partial resistance is associated with poor clinical outcomes in severe malaria patients.
4. To assess whether prior receipt of antimalarials is associated with artemisinin partial resistance in severe malaria patients
|
Uganda |
2024-02-09 23:26:22 |
2027-02-09 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Nsobya Samuel
ID: UNCST-2021-R012265
|
Ex vivo characterization of the drug susceptibility of malaria parasites in Uganda (Ex vivo study)
REFNo: HS4481ES
Primary objective
1. To characterize the ex vivo drug susceptibility of P. falciparum isolates collected from multiple sites in Uganda.
Secondary objectives
1. To characterize mutations that mediate drug resistance in P. falciparum isolates collected from multiple sites in Uganda
2. To characterize mutations that mediate drug resistance in banked P. falciparum previously collected from multiple sites in Uganda.
3. To culture, adapt and store P. falciparum isolates to enable studies of mechanisms of antimalarial drug resistance.
4. To measure drug levels in serum or plasma to help to understand treatment responses.
|
Uganda |
2024-07-09 18:35:24 |
2027-07-09 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Solomon Nsumba
ID:
|
Intelligent wearable systems for detecting medication errors at CoRSU Rehabilitation Hospital
REFNo: SIR360ES
To design and implement a low-power, real-time wearable system that seamlessly integrates with existing medical equipment, facilitating continuous monitoring and detection of medication errors during surgical procedures.,To prototype a software system capable of providing real-time feedback to medical personnel and generating automated records based on detected medication errors, integrating insights from the developed computer vision models.,To develop advanced computer vision models tailored to accurately detect and classify drug delivery events and associated errors, leveraging insights from the curated dataset,To curate a comprehensive video/image dataset capturing diverse medical drug events and errors in real-time during surgical procedures.,Overall Goal is to develop machine learning models that can detect medical drug events and errors in real-time during surgery.,
|
Uganda |
2024-07-10 13:29:17 |
2027-07-10 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
Samuel Obakiro Baker
ID: UNCST-2019-R000065
|
FORMULATION AND PRECLINICAL EVALUATION OF HERBAL PRODUCTS FOR MANAGEMENT OF DIABETES MELLITUS AND ITS COMORBIDITIES IN UGANDA
REFNo: HS4127ES
To analyze the phytochemical and pharmaceutical properties of the formulated herbal products,To assess the antidiabetic activity and toxicity of the formulated herbal products for the management of DM using in vitro and in vivo models,2. To formulate herbal products for management of DM ,1. To prioritize medicinal plants for formulation of herbal products for management of diabetes mellitus (DM),To develop standard herbal products for management of DM with proven preclinical evidence of efficacy and safety ,
|
Uganda |
2024-05-07 11:04:09 |
2027-05-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Samuel Obakiro Baker
ID: UNCST-2019-R000065
|
ASSESSMENT OF THE PHARMACEUTICAL SYSTEM CAPABILITIES AND CAPACITY TO MANUFACTURE, PROCURE AND DISTRIBUTE ESSENTIAL MEDICINES IN UGANDA (MaPDeM)
REFNo: HS5670ES
To explore the experiences and perceptions of communities on the utilization of pharmaceutical information systems regarding essential medicines,To evaluate the distribution networks and mechanisms for effective delivery of essential medicines to health facilities in Uganda. ,To assess the enablers and barriers for local pharmaceutical manufacturing of essential medicines in Uganda. ,To assess the pharmaceutical system capabilities and capacity to manufacture, procure and distribute essential medicines in Uganda. ,
|
Uganda |
2025-09-04 12:54:38 |
2028-09-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Sofie Bjerregaard Budhoo
ID: UNCST-2022-R010093
|
After Access to Justice: Exploring the development of local social dynamics and perceptions of justice in Northern Uganda after the International Criminal Court's (ICC's) Access to Justice Project
REFNo: SS1877ES
2. How will local perceptions of the ICC justice process, particularly in relation to reparations, develop over time after the end of the AJP?,1. What local patterns of behaviour and social dynamics will unfold over time in relation to the ICC justice process, particularly in relation to reparations, after the AJP has ended?,
|
Denmark |
2023-08-30 16:11:54 |
2026-08-30 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Sofie Bjerregaard Budhoo
ID: UNCST-2022-R010093
|
Waiting in the Social Aftermath of Access: An ethnographic examination of the development of local social dynamics and perceptions of justice in Odek in the wake of the International Criminal Court’s Access to Justice project
REFNo: SS1875ES
• How will local perceptions of justice and the International Criminal Court develop over time in Odek after the Court’s Access to Justice Project has ended?,• How will local patterns of behaviour and social dynamics develop over time in Odek in relation to the ICC’s justice processes and following reparations phase after the AJP has ended? ,
|
Denmark |
2023-07-27 20:59:38 |
2026-07-27 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Samuel Ojelel
ID: UNCST-2019-R000996
|
Tropical Important Plant Areas of Uganda
REFNo: NS479ES
(i) To assess conservation status of priority plant species to guide Identification of Important Plant Areas
(ii) To promote sustainable use and protection of Important Plant Areas by developing partnership with key stakeholders
|
Uganda |
2023-03-24 2:17:32 |
2026-03-24 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
HIV self-testing and linkage to care among Men having sex with Men (MSM). A trial Distribution through MSM networks in The Aids Support Organization (TASO)
REFNo: HS89ES
Aims 1. To conduct assess the barriers and facilitators of a formative research on the distribution strategy of HIVST kits through the peer networks (peers) of MSM
Aim 2. To conduct a pilot trial for evaluate the feasibility and acceptability of distributing HIVST kits using peers and linkage to HIV services.
Aim 3. To map and analyze the network of connections between peers and the peers they recruited during the trial.
|
Uganda |
2017-07-31 |
2020-07-31 |
Medical and Health Sciences |
|
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Controlled Trial of Game Changers: A Group Intervention
to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES
1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
|
Uganda |
2021-11-30 |
2024-11-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Anti-Retroviral Therapy Adherence Measurement Methods and Virological Failure in HIV infected Ugandans on long-term ART
REFNo: HS1949ES
1a. To describe incidence of virological failure in patients enrolled in the long-term ART cohort and assess the relationship between adherence to antiretroviral therapy (ART) measured either by patient self-report, appointment keeping and pill count and having virologic failure among HIV-infected Ugandan adults receiving long-term first line.
1b. To examine overall adherence measurement methods as a predictive test for VF among long term ART patients using a case control design taking patients confirmed with VF as cases and use incidence density sampling to sample for controls matched with time and age.
2. Determine the barriers and facilitators of ART adherence among patients on long-term ART at adult Infectious Diseases Institute (IDI) ART clinic using the Theoretical-Domains-Framework with 16 semi-structured, in-depth interviews with both people experiencing VF and those without VF, and ART providers (Medical Officers, Nurses, and counsellors)
|
Uganda |
2021-12-15 |
2024-12-15 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Peer Delivered HIV/Syphilis Self-Testing with Assisted Partner Notification Services for Men who Have Sex with Men (MSM) in Uganda
REFNo: HS3021ES
Estimate the cost-effectiveness of peer-delivered HIV/syphilis self-tests and partner services compared to facility-based testing.,Conduct a pilot randomized trial to pilot test the preliminary effectiveness of peer delivered HIV/syphilis self-tests and partner services versus facility-based testing., Conduct formative research to inform implementation of peer delivered self-tests for HIV and syphilis with partner services for Ugandan MSM. ,
|
Uganda |
2023-10-31 19:59:00 |
2026-10-31 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
UNDERSTANDING DRIVERS OF TB AND MALARIA PREVALENCE AND INCIDENCE, AND BARRIERS TO UPTAKE OF HEALTH SERVICES AND RETENTION IN CARE – COMMUNITY VOICE PERSPECTIVE IN NAMAYINGO DISTRICT
REFNo: SS2915ES
To collaboratively develop recommendations for driving sustainable impact and improving health outcomes in the context of TB and malaria.,To identify community-specific needs and gaps in current TB and malaria interventions and healthcare delivery systems.,To explore the socio-economic, cultural, and behavioral factors influencing the spread and persistence of TB and malaria within communities.,To engage directly with community members to understand their perspectives on the barriers and drivers of TB and malaria prevalence and incidence.,To understand the drivers of TB and malaria prevalence and incidence, as well as barriers to the uptake of health services and retention in care from a community voice perspective in Namayingo district,
|
Uganda |
2024-07-26 15:43:11 |
2027-07-26 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Amplifying Community Voices and Lived Experience of the Perceived Impact of Climate Change on Health among Community Health Workers in Namayingo District, Uganda
REFNo: SS4546ES
1.Document CHW experiences of the intersection between climate change and health among individuals, families, and communities.
2.Assess CHW experiences of how climate change affects their role and the health system more broadly.
3.Describe CHW perspectives on community strength and resilience in the face of the climate crisis, including local solutions.
4.Explore CHW recommendations for developing a climate-informed health workforce and climate-resilient health systems and communities.
|
Uganda |
2025-11-04 13:34:31 |
2028-11-04 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Solomon Mbina Adomi
ID: UNCST-2024-R015658
|
EFFECTS OF LYOPHILIZED LEAF EXTRACT OF KHAT (Catha edulis Forsk) ON HEPATORENAL SYSTEM AND LIPID METABOLISM IN HIGH FAT DIET INDUCED HYPERLIPIDEMIC MALE ALBINO WISTAR RATS
REFNo: HS5753ES
1. To characterize the bioactive compounds in lyophilized Catha edulis leaf extract using Gas chromatography-mass spectrometry (GC-MS) technique.
2. To determine the molecular interactions between bioactive compounds of Catha edulis leaf extract. and key proteins involved in lipid metabolism (leptin, adiponectin, and HMG-CoA reductase) using molecular docking analysis.
3. To determine the effect of lyophilized Catha edulis leaf extract on serum liver function parameters, (Alanine aminotransferase (ALT), Aspartate aminotransferase (AST) and
Alkaline Phosphatase (ALP), bilirubin, Albumin). in HFD-induced hyperlipidemic male
albino Wistar rats.
4. To evaluate the effect of lyophilized Catha edulis leaf extract on kidney function indices
(Urea, creatinine, serum electrolytes) in HFD-induced hyperlipidemic male albino Wistar
rats.
5. To determine the effect of lyophilized Catha edulis leaf extract on serum leptin and
adiponectin hormones levels in HFD-induced hyperlipidemic male albino Wistar rats.
6. To evaluate the effect of lyophilized Catha edulis leaf extract on serum lipid profile (Total cholesterol, High-density lipoprotein, low-density lipoproteins, and triglycerides) in HFD induced hyperlipidemic male albino Wistar rats.
7. To examine the effect of lyophilized Catha edulis leaf extract on the histology of the liver and kidney of HFD induced-hyperlipidemic male albino Wistar rats.
|
Nigeria |
2025-09-12 16:13:25 |
2028-09-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Solomon Mwije
ID: UNCST-2025-R022614
|
Potential and value of using Artificial Intelligence (AI) in Development Monitoring and Evaluation: Tools, Factors, Benefits, Challenges & Efficacy
REFNo: SS4958ES
Main Objective
1. To explore the extent to which AI is being used in M&E practices in Africa and the Asia-Pacific Regions.
Specific Objectives
1. To identify AI tools commonly used by M&E professionals and the M&E tasks where AI is used
2. To determine factors that influence professionals to use or resist AI when performing M&E tasks
3. To analyse the benefits professionals experience when using AI in M&E practices
4. To examine the risks and challenges professionals experience when using AI in M&E practices
5. To explore how professionals perceive capacities to use AI in M&E and the future impact of AI in M&E practices
|
Uganda |
2026-03-10 11:34:48 |
2029-03-10 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Solomon Mwije
ID: UNCST-2025-R022614
|
Exploring the potential of Photovoice toward strengthening social accountability through Citizen Science and Community-Based Monitoring initiatives. The RIDE-AFRICA’s Participatory Action Research Project, Kyenjojo District, Uganda
REFNo: SS4783ES
1. To understand how different photovoice mechanisms influence the citizen-state interface in extreme CBM initiatives.
2. To assess how different photovoice mechanisms influence citizen mobilization in extreme CBM initiatives.
3. To explore whether photovoice increases citizens’ and duty-bearers’ awareness in extreme CBM initiatives
4. To examine the extent to which photovoice influences citizens’ and duty-bearers’ actions in extreme CBM initiatives
|
Uganda |
2026-03-03 12:39:22 |
2029-03-03 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Solomon Lukoda
ID: UNCST-2025-R023096
|
RISE Uganda Context Analysis & Learning Support
REFNo: SS4837ES
1. Context Analysis: This scoping study will be conducted in Uganda to provide insights to the Foundation and its partners in the planning phase of the pilots.
2. Learning Support: This is aimed at filling existing knowledge gaps, facilitating learning and setting up adaptive management processes for the Foundation and its partners as the programme reaches the implementation stages, that will inform adaptation in existing countries and roll out to new countries.
|
Uganda |
2026-03-03 12:43:00 |
2029-03-03 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
|
Assessment of indoor air quality, risk factors and potential health effects among residents in an urban informal settlement in Kampala, Uganda
REFNo: SS996ES
To describe the potential health effects associated with indoor air pollution. ,To assess the factors associated with indoor air pollution among households. ,To determine the levels of indoor PM2.5, and Carbon monoxide (CO) in households., To determine levels of indoor air pollution, its associated risk factors and potential health effects among residents in an informal settlement in Kampala so as to generate information that can be used in design appropriate strategies, policies and practices that promote good air quality in households, hence mitigate health problems associated with indoor air pollution. ,
|
Uganda |
2021-09-03 |
2024-09-03 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
|
Healthcare workers’ Proficiency and Quality of Management for Snakebites in high burden Districts in Uganda
REFNo: HS2121ES
To explore the barriers faced in the management of snakebites in high burden districts in Uganda. ,To assess the quality of management for snakebites in high burden districts in Uganda.,• To assess the knowledge of health workers on snakebite management in two high burden districts in Uganda.,The overall objective is to assess health worker proficiency and quality of management of snakebites and associated barriers in high burden districts of Arua and Gulu so as to guide design of appropriate interventions to improve the quality of patient management and enhance favourable clinical outcomes. ,
|
Uganda |
2022-03-16 |
2025-03-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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