Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
ConfiSign HIV/Syphilis Combo Self-Test: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6687ES

Untrained users will either take part in the label comprehension study and results interpretation study (part A) or in the observed untrained user study (part B). Untrained users enrolled for the label comprehension and results interpretation study (part A), shall not participate in the observed user study (part B) and vice versa.,The primary and overall objective of this study is to evaluate the performance and the usability of the ConfiSign HIV/Syphilis Combo Self-Test in the hands of untrained users from a low prevalence HIV region (< 5%) who have no, or limited experience in self-testing. ,
Uganda 2025-10-29 16:22:26 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Partial Analytical and Clinical Performance Study focusing on Specimen Type Equivalence, Diagnostic Sensitivity and Specificity, and Usability Evaluation of ConfiSign HCV Pro.
REFNo: HS6742ES

3. Qualification of usability for professional use of ConfiSign HCV Pro through a label comprehension study and a results interpretation study which are to be completed by at least 3 laboratory professionals and at least 4 lay providers/healthcare workers.,2. Establish part of the clinical performance (diagnostic sensitivity and specificity) of ConfiSign HCV Pro using capillary whole blood samples.,1. Demonstrate the specimen type equivalence between capillary whole blood, venous whole blood, serum and plasma samples while using ConfiSign HCV Pro.,The general objective of this study is the partial evaluation of both clinical and analytical performance as well as qualification of usability for professional use of the ConfiSign HCV Pro according to parts of WHO TSS-16 (Part 1 - section 1.2.1, Part 2a - sections 2a.1.1 to 2a.1.3, Part 3a - sections 3a.1.1 to 3a.1.2) and CS (Annex I - Part I and Part II and Annex V - Table 2). For further details, see section 7.4.,
Uganda 2025-11-07 5:14:01 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ConfiSign HIV/Syphilis Combo Pro (REF: HISP001) Partial clinical and analytical performance study focusing on diagnostic sensitivity, diagnostic specificity, specimen type equivalence and usability evaluation of the ConfiSign HIV/Syphilis Combo Pro
REFNo: HS6989ES

3. Evaluate the usability of the ConfiSign HIV/Syphilis Combo using a label comprehension study and a results interpretation study which are to be completed by at least 3 lab technicians and 4 lay providers/healthcare workers,2. Demonstrate sample type equivalence between venous whole blood, serum and plasma samples while using the ConfiSign HIV/Syphilis Combo.,1. Determine parts of the diagnostic sensitivity and specificity of the ConfiSign HIV/Syphilis Combo using venous whole blood samples,
Uganda 2026-01-23 16:25:14 2029-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Evaluation of the Clinical and Analytical Performance and Usability of the KHB HIV/Syphilis Combo Rapid Test in the Hands of the Intended User
REFNo: HS7852ES

Establish the performance of the KHB HIV/Syphilis Combo Rapid Test in accordance with WHO TSS-27 (draft). This study will not cover all the parts of the TSS-27 (draft) but will focus on: - Part 1 Analytical Performance and Other Evidence o Aspect 3.05.02 ‘Validation of specimens’ o Aspect 3.05.06a ‘Potentially Interfering Substances’, Endogenous o Aspect 3.05.06b ‘Cross-reactivity’ o Aspect 3.06.04b ‘Usability: Label comprehension study (including instructions for use (IFU))’ o Aspect 3.06.04c ‘Usability: Results interpretation study’ - Part 2 Clinical Evidence o Aspect 4.02.03 Device specific clinical studies,Establish the performance of the KHB HIV/Syphilis Combo Rapid Test in accordance with WHO TSS-1. This study will not cover all the parts of the TSS-1 but will focus on: - Part 1 Establishing Analytical Performance Characteristics o Aspect 1.1 ‘Specimen Type’ (1.1.1 and 1.1.2) o Aspect 1.7.1 ‘Potentially Interfering Substances’, Endogenous o Aspect 1.7.2 ‘Cross-reactivity’ - Part 2 Establishing Clinical Performance Characteristics o Aspect 2.1 ‘Diagnostic sensitivity and specificity’ (2.1.1, 2.1.2 and 2.1.3)his study will not cover all the parts of the TSS-1 but will focus on:,
Uganda 2026-06-12 3:54:05 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sofia Forss Ingrid Fredrika
ID:
Comparing the Effects of Early Experience and Cognitive Plasticity across the Great Ape Species
REFNo: NS27ES

The main aim of the project is to compare developmental- and experience effects both within and across ape species. First, I aim to investigate the influence of rearing histories (mother reared, wild born, sanctuary born, zoo housed, sanctuary housed, human hand reared etc) on cognitive skills within ape species. Second, by acknowledging individual differences due to rearing histories, this project will deliver meaningful comparisons, where individuals of similar experiences are compared across great ape species. In addition, it allows me to evaluate the strength of experience effects by examining if the change in problem-solving abilities linked to rearing experiences and human contact can even outweigh intrinsic species differences.
Finland 2017-09-12 2020-09-12 Natural Sciences Non-degree Award
Sachin Gathani Gathani
ID:
Effect of Covid-19 lockdown measures on coffee farmers in Central and Western Uganda
REFNo: SS486ES

This study aims to understand the effect of COVID-19 and the consequent lockdown
measures on coffee farming households in the JDE Farm College a program being
implemented by TechnoServe (a non-profit organization). JDE is working in partnership with Technoserve to train coffee farmers on coffee agronomy best practices, helping them improve
the quality and yields of their coffee trees, which in turn will increase their income in the long term. Farmers are enrolled in the training program every 2 years in what is referred to as a
“cohort”. Enrolled farmers come together and form a focal farmer group and a farmer trainer is appointed to run the training sessions. Coffee demo plots are implemented in order to train farmers in real-life conditions. The trainings are conducted every month and attendance is tracked. Laterite is a research, data and advisory firm with offices in Kampala who is partnered with TechnoServe to provide research support for the monitoring and evaluation activities of the TechnoServe Farm College Program.
The main objective of the study is to generate timely data and insights for TechnoServe and coffee industry stakeholders on how coffee farming households that are part of their agronomy training program are affected by COVID-19 crisis and the consequent lockdown measures to address Covid-19. This will be useful for TechnoServe, to inform their programming including targeting interventions to areas that need them most and considering options for redirecting
resources from coffee agronomy to other types of training.
The results from this study will result in monthly briefs (not an academic study) that
demonstrate farmer’ knowledge of COVID-19 and how the lockdown measure may have
affected their farming activities including access to input, farms and markets.
Kenya 2020-06-30 2023-06-30 Social Science and Humanities Non-degree Award
Sydney Gourlay
ID:
Advancing methods for measuring agricultural productivity in household surveys
REFNo: SS2185ES

In a world with increasing climate change and intensifying food insecurity, agricultural productivity is central to development. Increasing agricultural productivity requires a detailed understanding of cultivated land and its limitations, and how these shortcomings can be addressed. Towards this end, getting more reliable data on land quality and quantity, two critical elements in agricultural production, is essential for accurately estimating agricultural productivity indicators like crop yield as well as for correctly identifying key agricultural relationships, such as the often-cited inverse land size-productivity relationship. Recent technological advancements both in the areas of in field soil measurement as well as GPS-based area measurement offer promises to this respect. However, there is a need to test and validate some of the most promising methods to assess their cost-effectiveness and potential for scalability in the context of large-scale surveys and vis-ŕ-vis more traditional improved approaches such as the elicitation of subjective and observational information in household level questionnaires.

The primary objectives of this study are:
1. Improve the measurement of agricultural productivity in household surveys
2. Test and validate innovative methods for soil health and land area measurement in the context of household surveys
3. Assess cost-effectiveness of the different methods for scaling up in national surveys

The objectives, methods and relevant literature are presented in the proposal (attached), by domain of research: soil health, land area measurement, and agricultural production measurement.

USA 2023-12-22 22:53:15 2026-12-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Gray Blair
ID: UNCST-2025-R019416
Understanding the Role of Play in Promoting Psychosocial Well-being and Learning Among Children in Refugee and Host Communities: A Contextual Study in Adjumani and Obongi Districts
REFNo: SS4275ES

Objectives of the Study This context study aims to generate evidence on how children, parents and guardians, and educators in Adjumani and Obongi districts understand, perceive, and practice play and its implications for education and psychosocial well-being. In particular, this study aims to: ? Understand the cultural and contextual meanings of play and well-being among children, parents and guardians, ECD caregivers and teachers, and community members in West Nile, ? Explore the perceptions of the role of play in supporting children’s psychosocial well-being and learning, ? Document existing practices and norms related to play and psychosocial well-being within families/at home, schools, and communities, and ?Identify barriers and enablers to using play-based learning to support children’s psychosocial well-being.
New Zealand 2025-09-26 18:28:13 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Shaheen Memon Mohamed Zahiruddin
ID:
APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES

1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.

Kenya 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
Shai Andre Divon AndrĂ©
ID:
Community Based Policing: Uganda Case Study (ICT4COP)
REFNo: SS231ES

The Uganda case study provides an insight into African perspectives on COP. The overarching objective of the study is to explore the influence and impact of the Ugandan approach to COP. As such the research in Uganda will focus on: police training, application of policing/community policing and impacts of policing on communities. Parts of the research in Uganda may link to the South Sudan case study including through the impact of Uganda’s approach to policing on South Sudan through police training. The focus on the training component will mainly observe the efforts of the Government of Uganda to assist the crisis in South Sudan through police training, but also on the Ugandan concept of COP and the official structures for the implementation of COP. The focus on application of policing/community policing will explore police-community relations in selected areas in Northern Uganda. This component will also include an element bridging into the South Sudan case study by exploring the dynamics between Ugandan host communities and settled refuges from South Sudan, concentrating on police-community relations and the unique challenges that Ugandan police faces in such contexts. The impacts of policing on communities element will explore how both the police and communities collaborate and how has this collaboration affects a range of human security issues in contexts. To achieve the overarching objective the research will revolves around the following sub-objectives: 1. To analyze COP applied in Northern Uganda 2. To investigate COP applied in a variety of socio-cultural contexts in Northern Uganda 3. To understand COP training provided by Uganda to other African nations
Norway 2018-10-30 2021-10-30 Social Science and Humanities Non-degree Award
Shamilah Namusisi
ID:
Improving Household and Community Practices to reduce human contact with bats in Bundibugyo District
REFNo: SS1406ES

To determine the effectiveness of the “Living Safely with Bats” model developed by the USAID-PREDICT project at a community level. ,Improve community knowledge of, and increase uptake of safety practices through a multi-pronged social and behavior change (SBC) strategy.,Engage local women, women groups and school clubs in testing out plants that repel bats due to their scent, including as mint and rosemary.,Identify locally available and affordable materials to keep bats out of homes and community buildings. ,The overall goal of this intervention is to reduce the risk of exposure from pathogens arising as a result of human contact with bats by deterring bats from entering houses and buildings, as well as improving household and community safety practices once the bats have already entered or roosted.,
Uganda 2022-09-23 11:53:17 2025-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Shamirah Najjinda
ID:
Family support, entrepreneurial resources, resilience and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda
REFNo: SS2842ES

To determine the levels of understanding of entrepreneurial wellbeing by women entrepreneurs in Uganda.To establish the relationship between family support and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To examine the relationship between entrepreneurial resources and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To explore the influence of entrepreneurial resilience on the entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.
Uganda 2024-07-10 13:40:22 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
NAKAJUBI SHAMUSI
ID: UNCST-2024-R003579
“BLOCKCHAIN-BASED FRAMEWORK FOR INTRA-DATA SHARING IN SAVINGS AND CREDIT COOPERATIVE SOCIETIES (SACCOS)” A CASE OF WAZALENDO SACCO - UGANDA
REFNo: SIR412ES

To Evaluate the framework for intra-data sharing in SACCOS.,To develop a Blockchain-based Framework for intra-data sharing in SACCOS.,To examine the challenges faced in the current intra-data sharing processes in SACCOS,To establish the current state of the art and Intra-data sharing practices in SACCOS,The general objective of this study will be to develop a Blockchain-based Framework for intra-data sharing in SACCOS. ,
Uganda 2024-11-19 7:28:29 2027-11-19 Engineering and Technology Non-Clinical Trial Degree Award
Shana Warren
ID:
Vitamin A Supplementation (VAS) Post Event Coverage Survey (PECS) in Uganda
REFNo: SS1261ES

To conduct a PEC survey for the October-November 2021 round of the ICHD in Uganda,
USA 2022-04-21 2025-04-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
SHANI BUDIGOLI DEODATUS
ID:
Prevalence, clinical manifestations, relationship with viral load of cutaneous disorders among children and adolescents living with HIV attending Mbarara Regional Referral Hospital.
REFNo: HS1265ES

1. To determine the prevalence of cutaneous disorders among children and adolescents living with HIV attending pediatric infectious Diseases' clinic at MRRH.
2. To describe the clinical manifestations of cutaneous disorders among children and adolescents living with HIV attending paediatric infectious Diseases’ clinic at MRRH.
3. To determine the relationship of cutaneous disorders and viral load among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.
4. To assess the relationship between cutaneous disorders and CD4 counts among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.



Tanzania 2021-07-26 2024-07-26 Medical and Health Sciences Degree Award
Sharon Muita
ID: UNCST-2024-R003345
Social Marketing Research to Understand Barriers to and Increase Consumption of Fortified Whole Grains in Uganda
REFNo: SS3251ES

?Generate insights for development of a Social and Behavior Change Communication (SBCC) campaign. A big idea was developed based on Rwanda Survey findings. Consumer Focus Group Discussions will be instrumental in generating insights for adopting the big idea in Uganda to prepare the SBCC campaign for execution. ?It is understood that behavior change campaigns are contextual and must consider the intersections of diverse identifies to be effective for the desired behavior change and ensure they do no harm by reinforcing negative stereotypes and further marginalizing vulnerable populations. The campaign intends to shift behavior towards increased consumption of fortified whole grain maize flour and develop SBCC tools for use in awareness campaign activities within schools, households and larger communities. ? ,?Gather insights from key stakeholders, including policy makers and nutritional experts, on whole grain promotion and consumption. The study seeks to establish the demand, profitability, and ease of access of whole grains especially for the millers and traders both in the retail and wholesale space, highlighting gender, social status, cultural and rural/urban specific challenges, and opportunities that shape the whole grain supply environment. ,?Analyze the school feeding ecosystem. This study will seek to understand school feeding programs including key actors and their relationships, establishing the key decision makers, cost, policy influencers, schools\' management systems and structure, and the school feeding program’s value chain. Gender analysis will consider composition, leadership structures, knowledge and decision-making power across the actors, systems and processes that result in or facilitate school feeding programmes. ,?Identify factors influencing the consumption choices of whole grain maize flour at household and community levels. ?This study will ascertain the awareness, cultural and social expectations, roles and responsibilities, access, decision-making, purchase power and habits, barriers and drivers, underlying preferences and gender dynamics influencing consumption of whole grains in Uganda. It will evaluate consumer acceptance and satisfaction of whole grain maize flour based on sensory attributes such as taste, texture, appearance and overall preference. ,1. ?Understand consumers and food consumption patterns. ?This research aims to understand consumer’s knowledge, attitudes and practices as well as perceptions, preferences, and habits in their choice of food consumed at the household and in particular, both refined and whole grains. It will explore the influencers of food choices, the motivators, enablers, and inhibitors to maize flour consumption among women and men, boys and girls and examine the influence of gender, demographics, beliefs and practices, geolocation, nutritional awareness and access, social expectations and agency and other social constructs on personal and household food provision dynamics and whole grains consumption. It will also assess bases of minimum dietary diversity for both men and women in relation to their consumption patterns at the household level. ,?The overall objective is to understand consumer whole grain eating habits with a view of shifting consumer behavior to the consumption of fortified whole grains. ,
Kenya 2024-10-08 16:35:40 2027-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sharon Pang Sze Lu
ID:
Transform Randomised Controlled Trial in Uganda
REFNo: SS1823ES

To evaluate the impact of the Transform program on the key indicators in values, health and livelihood in Uganda
Hong Kong 2023-08-25 8:07:30 2026-08-25 Social Science and Humanities Clinical Trial Non-degree Award
SHARON NAMIIRO MIRIAM
ID: UNCST-2023-R006661
Prevalence of Human Papilloma Virus in lung cancer tumors of adult people with and without HIV, and its association with lung cancer stage at diagnosis.
REFNo: HS6375ES

1. To determine the prevalence of Human Papilloma Virus (HPV) in primary lung cancer tumors of adult patients living with and without HIV 2. To compare the most prevalent HPV subtypes in the primary lung cancer samples of adult people living with and without HIV in Uganda. 3. To determine the association of HPV with lung cancer stage among adults with and without HIV.
Uganda 2025-09-09 16:45:06 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
sharot kintu
ID: UNCST-2024-R016314
CARING FOR CHILDREN WITH SICKLE CELL DISEASE: A QUALITATIVE STUDY OF PARENTS/CAREGIVERS’ EXPERIENCES IN WAKISO DISTRICT
REFNo: SS3536ES

The study seeks to achieve four primary aims/objectives: 1.To understand and document the experiences of parents/carers in looking after children with SCD in Wakiso District. 2.To assess the ways in which the social cultural context in Wakiso affects the ability of the parents to care for children with SCD. 3.To explore the care related needs of the parents that can help them improve their role performance. 4.To identify SCD related with Gender Based violence against caregivers/parents in the community
Uganda 2025-02-14 15:44:16 2028-02-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
SHEBA  NAKACUBO GITTA
ID:
How can UK Health Worker Volunteers Effectively and Sustainably Support the Development of Ugandan Health Workforce?
REFNo: HS837ES

1. To provide an overview of current approaches and priorities to health worker volunteer placements in Uganda;
2. To identify the priority needs for health worker volunteer placements in partnership with the Ministry of Health;
3. To give insight into the volume of health worker placements available and make recommendations on how such schemes can be designed to achieve mutual benefit for the UK, Uganda and other host countries.

Uganda 2020-11-02 2023-11-02 Medical and Health Sciences Non-degree Award
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