Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Andrew Tusiime
ID: UNCST-2025-R021675
INVESTIGATION OF ELECTROCATALYTIC ACTIVITIES OF NEW HETEROLEPTIC COPPER (I) DITHIOLATE COMPLEXES TOWARDS HETEROGENEOUS HYDROGEN AND OXYGEN EVOLUTION REACTIONS
REFNo: NS1069ES

1.To synthesize two new heteroleptic copper(I) dithiolate complexes [copper (I)bis(3,4-dimethoxyphenylacetonitrile-1,1-dithiolato)(2,2′-bipyridine)(triphenylphosphine), copper(I) bis(benzene-1,2-dithiolato)(2,2′-bipyridine)(triphenylphosphine)].

2.To characterize the newly synthesized heteroleptic copper(I) dithiolate complexes ( NMR, FT–IR, UV–Vis and SEM–EDX).

3.To investigate electrocatalytic properties of the new heteroleptic copper (I) dithiolate complexes towards heterogeneous hydrogen and oxygen evolution reactions.

Uganda 2025-12-18 17:54:31 2028-12-18 Natural Sciences Non-Clinical Trial Degree Award
Micheal Ivan Lyazi Micheal Ivan
ID: UNCST-2025-R021640
An Assessment of Gender Integration in Equity Accelerator Fund (EAF) Implementation in Uganda
REFNo: SS4547ES

1. 1. To describe the specific gender-related barriers to immunization access among Uganda’s zero-dose population archetypes. 2. 2. To assess the implementation of EAF gender integration strategies. 3. 3. To identify gaps in the implementation of EAF gender integration strategies. 4. 4. To explorer how gender integration influences the number of ZD/ under immunized cases across the different population architypes in the study Geographies.
Uganda 2025-11-21 14:44:56 2028-11-21 Social Science and Humanities Non-degree Award
Rik Lubbers
ID: UNCST-2025-R021634
Exploring Vulnerability and Resilience in Accessing and Providing Nutrition-Sensitive Maternal and Child Health Services During Floods, Droughts, and Compound Events in Katakwi, Uganda: A Multi-Hazard Qualitative Study.
REFNo: HS7019ES

To characterise how floods, droughts, and compound climate events shape vulnerability and resilience in accessing and providing nutrition-sensitive maternal and child health services in Katakwi District, Uganda. Specific objectives: To describe caregivers’ perceived access barriers and decision-making during and after floods, droughts, and compound events. To assess perceived facility-level constraints affecting continuity of maternal and child health services across referral tiers. To document household, provider, and facility-level adaptation strategies that sustain or restore services. To generate actionable, tier-specific recommendations for district preparedness and response.
Netherlands 2026-02-18 12:49:03 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Joan Kekimuri
ID: UNCST-2025-R021625
MUJAGUZO ROYAL DRUM OF BUGANDA KINGDOM: CHRONICLES OF ITS ORIGIN, MEANING-MAKING, AND CONTINUITY
REFNo: SS4868ES

1. To document the history of the Mujaguzo royal drum. 2. To identify qualities of Mujaguzo Royal Drum as a mystical art form. 3. To disinter the rituals that encompass interregnum meaning of oral continuity from one rule to another 4. To visually interpret the mystical meaning attached to Mujaguzo royal drum through visual art.
Uganda 2026-02-20 15:08:03 2029-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deogratius Ssemwanga
ID: UNCST-2025-R021563
Performance Evaluation for Diagnostic Tests
REFNo: HS6649ES

Primary Objective

The overall objectives of this performance evaluation are:

• To verify the performance characteristics of new on-the-market NAATs and antigen RDTs.
• To establish well-characterized viral pathogen sera/plasma reference panels to support evaluation efforts and quality assurance.

• To evaluate the performance characteristics of new, on-the-market, EIAs and RDTs (IgA, IgG and IgM).
• To train laboratory and POC staff in biosecurity and the required technical skills to perform diagnostic testing.

Specific Objectives:

• To confirm whether or not a new NAAT complies with the manufacturer’s specifications,
• To determine the performance equivalence of new on-the-market NAATs, including POC devices, using available gold standards (or any other comparatively/equally as good WHO/FDA approved NAAT),
• To determine the performance equivalence of new on-the-market antigen tests against the gold-standard NAAT,
• To determine the sensitivity and specificity of new on-the-market diagnostic EIAs and RDTs against a gold-standard method,
• To evaluate the operational characteristics of new on-the-market immunoassays. Operational utility characteristics that may be considered include;
o ease of performance
o specimen type utility
o inter-reader variability
o reaction endpoint stability
o suitability for use in facilities with limited infrastructure (no/limited electricity, no/limited clean water)
• To document SOPs and train laboratory staff in performing testing using recommended diagnostic tests,
• To establish a repository of well-characterized natural infection and vaccination sera/plasma as well as swabs/extracted RNA to support future evaluation and verification of immunoassays.
• To establish a cohort of natural infection and vaccinated cases in the country whose samples and demographic characteristics will be used to help understand the dynamics of human immunity development to viral infection in order to inform the clinical interpretation of the various diagnostic assays.

Uganda 2025-10-24 17:31:36 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel  Luyirika BK
ID: UNCST-2025-R021521
Destigmatizing Breast Cancer: Village Health Teams Using a Video Education Tool
REFNo: SS4394ES

1)Improve knowledge about breast cancer among VHTs 2)Evaluate if community members found this video tool to be an acceptable and helpful way to learn more about breast cancer. 3)Evaluate if VHTs found this video tool to be an acceptable and helpful way to share information about breast cancer.
Uganda 2025-12-05 18:37:27 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Caroline Gotsche Isabelle
ID: UNCST-2025-R021504
Antenatal syphilis testing in central Uganda - Exploring provider-level factors affecting maternal syphilis testing coverage
REFNo: HS6671ES

1. Mapping the current body of literature of syphilis testing in ANC services.This will allow us to obtain an overview on the current state of syphilis testing among pregnant women in ANC services in Uganda. 2. Understanding impeding and facilitating factors of syphilis testing in ANC services. Investigating providers` (Health Care Workers (HCW), midwives, nurses and physicians) knowledge of syphilis, and their experiences, perceptions, ideas and interest in syphilis testing will be essential to gain deeper understanding of these factors. Additionally, providers’ interest and ideas on engaging partners in antenatal syphilis testing will be explored to address the issue of re-infection in pregnant women. To gain an overview of a pregnant woman’s journey through the clinic, paying particular attention to how syphilis screening fits into antenatal care clinic observations will be conducted. 3. Exploring syphilis self-testing as a novel syphilis testing strategy in ANC services.
Investigating policy makers`, providers’ and pregnant women’s understanding and interest in the use of syphilis self-testing will be investigated. Whether the use of secondary distribution of self-test kits to partners of pregnant women to enhance partner engagement may be an acceptable approach among pregnant women will be also examined.
Germany 2025-11-07 5:12:16 2028-11-07 Medical and Health Sciences Non-Clinical Trial Degree Award
JACOB BIBOHERE
ID: UNCST-2025-R021298
Assessment of CDC Data Triangulation Activities to Enhance Immunization and Vaccine-Preventable Disease Surveillance Programs in Selected African Countries
REFNo: HS6596ES

1.To assess the extent to which data triangulation has been integrated into the existing immunization and/or VPD surveillance staff workload, program processes, and practices at national and sub- national levels. 2.To identify programmatic successes, challenges, enabling factors, and innovations reported by immunization and/or VPD program staff through the application of triangulation analytic tools. 3.To examine the immunization programmatic decisions, actions, and outcomes that have been informed by the use of data triangulation concepts. 4.To explore and identify sustainability strategies and recommendations for ensuring that data triangulation and existing tools remain integrated into routine program activities.
Uganda 2025-10-29 12:42:52 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nora Doukkali Elamajidi
ID: UNCST-2025-R021292
Practicing Time in Humanitarian Waiting-scapes
REFNo: SS4632ES

The aim of this research is to explore how humanitarian waiting-scapes are shaped, sustained, and transformed. The specific objectives are: A. To analyze how humanitarian actors (local and international) design and manage waiting in aid sites, including by documenting the spatial and rhythmic dimensions of waiting in specific places (medical points, distribution areas, information offices). B. To examine how people affected by humanitarian crises experience these humanitarian practices of waiting (i.e. in terms of physical and psychosocial well-being, dignity, economic), adapt and negotiate them. C. To observe the social dynamics that emerge in waiting situations (mutual support, resource sharing, tensions and violence). D. To develop a better understanding of how waiting could become more dignified and/or avoided.
France 2026-01-30 10:12:35 2029-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
Nada Eissa O.
ID: UNCST-2025-R021279
Fiscal Devices and Value-added Taxes in Uganda: An Evaluation of How Different EFRIS Platforms Relate to Tax Compliance Across Firms in Kampala
REFNo: SS4435ES

To evaluate the impact of the adoption and use of Electronic Fiscal Devices (EFDs) within the EFRIS system on VAT declarations and payments by firms in Kampala, Uganda, and to understand the factors influencing firms' compliance and the effectiveness of EFDs in reducing VAT evasion.
USA 2026-01-30 19:14:26 2029-01-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Yueh-ya Hsu
ID: UNCST-2025-R021249
The Impact of Microcredit for Refugees and Host Communities
REFNo: SS4473ES

The aim of this project is to provide some of the first evidence on the benefits of extending credit to refugees, with a focus on documenting both financial and psychosocial gains. The team's close partnership with the UNHCR and the World Bank ensures that the results can be quickly disseminated to key actors in this space. UNHCR operates in over 136 countries and collaborates closely with implementing partners to develop and disseminate impactful programs. They are eager to build a body of evidence to inform the pursuit of certain policies over others, and facilitate discussions with local governments about implementing these policies.
Taiwan 2025-10-17 19:36:16 2028-10-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Karen Ademun Helmy
ID: UNCST-2025-R021192
Assessing the impact of floods on access to diabetes treatment in Kasese district.
REFNo: HS6730ES

Objective 1: To assess how flooding disrupts the availability and accessibility of diabetes treatment facilities in Kasese District. Objective 2: To assess how flooding disrupts the availability and accessibility of diabetes treatment facilities in Kasese District. Objective 3: To explore the coping mechanisms of diabetes patients to the negative impacts of floods on access to diabetes treatment services.
Uganda 2026-01-30 16:47:56 2029-01-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph Matovu Wasswa
ID: UNCST-2025-R021145
Understanding Power, Institutions, and Policy Dynamics: A Political Economy Analysis of Youth Employment in Uganda
REFNo: SS4607ES

Research Questions The political economy analysis aims to answer two overarching research questions: I. How can current policies and regulatory frameworks be activated and enhanced to provide dignified and fulfilling work opportunities for youth in Uganda? II. What industrial and trade policies and/or plans will enable Uganda to leverage its demographic transition, the 4th industrial revolution, and the evolving digital economy to create adequate opportunities for dignified and fulfilling work for Ugandan youth? Purpose and Objectives The main purpose of this study is to examine how political, institutional, and economic structures interact to shape youth employment outcomes in Uganda. Specifically, the research seeks to: • Map the formal and informal policy, regulatory, and institutional frameworks governing youth employment. • Analyse the interests, incentives, and power dynamics of key actors who influence or obstruct youth employment reforms. • Understand the lived experiences, perceptions, and aspirations of young people in relation to work, inclusion, and voice. • Identify enablers and constraints to the implementation of effective and inclusive employment strategies. • Generate context-sensitive, actionable recommendations for policy and institutional reform.
Uganda 2025-11-26 14:32:03 2028-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cathleen Morey
ID: UNCST-2025-R021152
From Knowledge to Practice: A Mixed Methods Evaluation of a Diabetes Education Program for Healthcare Providers in Kasese District, Uganda
REFNo: SS4861ES

Main Objective To evaluate the effectiveness and impact of Diabetes Empowerment International’s (DEInt.) diabetes education programs on healthcare providers in Uganda and to examine the cultural and systemic factors that influence diabetes education and care delivery within the broader community context. Specific Objectives 1. To evaluate changes in provider knowledge, confidence, and diabetes care practices following participation in DEInt. conferences. 2. To explore community-level perspectives on diabetes education and care. 3. To identify barriers and facilitators affecting diabetes care delivery. 4. To generate recommendations to improve DEInt.’s educational programs and inform future interventions.
USA 2026-02-10 16:20:44 2029-02-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lucrezia Rovati
ID: UNCST-2025-R021085
Evaluation of a Clinical Decision-Support App for Emergency Care in a Rural Ugandan Hospital: A Pilot Randomized Crossover Simulation Trial
REFNo: HS6836ES

The primary objective is to determine whether the newly developed OASES clinical decision-support App improves frontline clinicians’ adherence to evidence-based World Health Organization (WHO) and Uganda Clinical Guidelines during the management of simulated emergency cases of diarrhea, dyspnea, and seizures in a rural outpatient department. The secondary objectives are to assess whether the OASES App improves triage accuracy using the Interagency Integrated Triage Tool, diagnostic accuracy at both the initial and post-investigation stages, and the appropriateness of disposition decisions; to determine whether App use enhances clinicians’ process quality by increasing adherence to guideline-recommended history taking and physical examination; to compare time required to complete simulated emergency cases under App-assisted versus standard practice conditions; to evaluate usability, perceived usefulness, trust, satisfaction, and feasibility of the App through structured questionnaires and qualitative interviews.
Italy 2026-01-30 9:27:17 2029-01-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Opportuna Kweka Leo
ID: UNCST-2025-R021025
STRENGTHENING KNOWLEDGE, EVIDENCE USE AND LEADERSHIP IN THE GLOBAL SOUTH ON FORCED DISPLACEMENT: WITH A FOCUS ON EAST AFRICA
REFNo: SS4309ES

Conduct research on forced displacement, namely refugees, internally displaced persons and development/conservation/disaster and climate changed induced displacement). (ii) Build capacity on forced displaced issues through seminars, training of masters, PhD and postdoctoral students doing research on forced displacement. (iii) Work with policy makers to discuss the state of the knowledge, constraining factors and possible angles for inclusion of those marginalized. (iv) Work with NGOs to conduct outreach activities either expanding and upscaling existing outreach activities (originating from refugees or external actors) or start new empowerment programmes on social and legal inclusion. (v) Develop a master’s programme on forced displacement, which will be offered in the Department of Geography at the University of Dar es Salaam
Tanzania 2025-11-04 13:40:10 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mirembe SarahAngella
ID: UNCST-2025-R021000
Influence of Women's Participation In The Rice Value Chain on Household Dietary Diversity in Eastern Uganda
REFNo: SS4586ES

1. To examine the extent of women’s participation in the rice production, processing, and marketing activities within selected rice-oriented households in Namasagali sub-county, Eastern Uganda. 2. To identify the institutional factors that influence women’s participation as rice value chain actors at the household level. 3. To assess the dietary diversity of rice-oriented households in Namasagali sub-county, Eastern Uganda. 4. To establish a relationship between women’s participation and household dietary diversity.
Uganda 2025-12-01 21:16:33 2028-12-01 Social Science and Humanities Degree Award
Isabelle Cohen
ID: UNCST-2025-R020977
Evaluating a “nearly free hour” for health centers in rural Uganda
REFNo: SS4726ES

This study has four specific objectives: 1. Evaluate the effects of a discounted, group visits window on ODH health centers, including how many ultrapoor patients visit the clinic during the discounted, group visits window. 2. Compare the discounted window to an all-day discount to understand whether a time-limited discount is (relatively) more effective at screening in the UP. 3. Document the extent to which the discounted window cannibalizes revenue by shifting patients from other times of day to the discounted window. 4. Analyze whether discounts encourage earlier treatment for mild/moderate malaria, and correspondingly reduce visits for severe malaria.
USA 2026-01-27 19:41:22 2029-01-27 Social Science and Humanities Clinical Trial Non-degree Award
DANIEL ELAMU
ID: UNCST-2025-R020928
PREVALENCE OF MALARIA AND HIV IN UGANDAN CHILDREN WITH TRAUMATIC BRAIN INJURY; AN EARLY OUTCOME STUDY.
REFNo: HS6781ES

Primary objective: To determine the prevalence of malaria (by RDT and PCR) and HIV among children presenting with traumatic brain injury at Mulago National Referral Hospital in 8 months.
Secondary Objective: To assess the impact of malaria parasitemia and/or HIV co-infection on short-term functional recovery, measured by Health-Related Quality of Life (HRQoL) at one-month post-discharge.
Uganda 2025-11-21 13:47:46 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ali Waiswa
ID: UNCST-2025-R020882
ARTIFICIAL INTELLIGENCE AND DEEP LEARNING BASED IRIDOLOGY FOR DETECTION OF COLORECTAL CANCER
REFNo: HS6756ES

To determine the sensitivity of AI and deep learning based iridology for detection of colorectal cancer in Uganda over a period of one year.
To determine the specificity of AI and deep learning based iridology for detection of colorectal cancer in Uganda over a period of one year.

Uganda 2025-11-13 16:40:17 2028-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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