Sarah Lofgren
ID: UNCST-2019-R001647
|
The Growth Study- Group Therapy In HIV For Depression In Uganda
REFNo: HS493ES
Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
|
USA |
2019-12-09 |
2022-12-09 |
Medical and Health Sciences |
|
Non-degree Award |
|
Sarah Lofgren
ID: UNCST-2019-R001647
|
Supervised Treadmill intervention to Reduce Inflammation and Depression through Exercise in HIV: The STRIDE Pilot Study
REFNo: HS3358ES
The objective of this study is to determine the feasibility and acceptability of an aerobic intervention via a treadmill among individuals with HIV and depression in Uganda.
3.1 Primary Endpoint: Feasibility and acceptability of Exercise as a treatment for depression in Ugandans with HIV. This will be measured by:
-Percent completion of the prescribed aerobic exercise intervention, as assessed by research staff logging participation.
3.2 Secondary Endpoint(s)/ Outcome(s):
- acceptability of the intervention assessed via a post intervention survey
-feasibility and acceptability of using a wearable exercise tracker to assess the volume of exercise, based on calories burned and steps achieved, during the intervention period among Ugandans with HIV and depression.
- measure the mean and standard deviation of baseline and 8-week serum BDNF and IL-6 level to estimate an effect size and power a future study.
- measure the mean and standard deviation of baseline and 8-week depression score via PHQ-9 to estimate an effect size and power a future study.
- measure the mean and standard deviation in aerobic fitness baseline and at 8 weeks measured via METS/watts achieved and total time/distance to estimate the effect size for a future intervention.
|
USA |
2024-02-26 13:41:23 |
2027-02-26 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
|
New approaches for the diagnosis of Kaposi's sarcoma
REFNo: HS28ES
To evaluate two novel diagnostic approaches for KS that may be eventually deployed with portable, point-of-care techniques. One approach features confocal microscopy and the other approach uses nucleic acid amplification. We shall compare these new approaches with the gold standard of histology from a traditional skin punch biopsy to determine the sensitivity and specificity of each new approach.
|
Uganda |
2016-12-13 |
2019-12-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
|
ESTIMATION AND EXPLANATIONS FOR THE HYPERTENSION SCREENING GAP AMONG HIV-INFECTED PATIENTS IN HIV PRIMARY CARE.
REFNo: HS118ES
1. Estimate the screening gap for hypertension among HIV-infected adults on ART attending Uganda Cares HIV primary care clinics in Masaka, Rakai and the St. Balikudembe Clinic in Kampala, Uganda over 12 months.
2. Document explanations for the screening gap for hypertension from the perspective of health providers at the Uganda Cares HIV primary care clinic in Masaka, Rakai and St. Balikudembe Clinic in Kampala, Uganda.
|
Uganda |
2017-11-28 |
2020-11-28 |
Medical and Health Sciences |
|
Non-degree Award |
|
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
|
EVALUATION OF THE USE OF TELEDERMATOLOGY AMONG PRIMARY CARE PATIENTS IN KAMPALA
REFNo: HS3655ES
Aim 3: Define the distribution of dermatologic diagnoses that arise in primary care settings in which TD is used and their subsequent management. ,Aim 2: Evaluate the barriers and facilitators to implementation of the TD service,Aim 1: Describe the utilization of TD in ambulatory care settings. ,
|
Uganda |
2024-02-02 11:24:53 |
2027-02-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
|
Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS)
REFNo: HS5498ES
•Aim 1: Refine SkinScan3D Technology and Usage Protocols for Routine KS Imaging:
•Aim 2: Compare Reproducibility and Accuracy of KS Lesion Size Measurements Between SkinScan3D and Current Standard of Care Measurement.
•Aim 3: Validate and Optimize SkinScan3D Clinical Workflow in Real-World Settings.
|
Uganda |
2025-04-11 16:47:49 |
2028-04-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
|
PATIENT AND PROVIDER PERCEPTIONS, EXPERIENCES, AND INTERVENTION SUGGESTIONS AFTER HIV/AIDS CARE FUNDING REDUCTIONS
REFNo: HS7138ES
To characterize comprehension of U.S. funding reduction for HIV/AIDS care and the implications on care among persons living with HIV.
2. To determine the initial impact of U.S. funding reductions for HIV/AIDS care by eliciting the experiences of persons living with HIV and their healthcare providers.
3. To understand perceptions regarding proposed or enacted interventions to maintain care after U.S. HIV/AIDS care funding reduction among providers and persons living with HIV.
|
Uganda |
2026-04-10 15:36:15 |
2029-04-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Anne Kantel
ID:
|
Situating Legitimacy: Encounters between State-Based and Local Fisheries Lifeworlds in Uganda
REFNo: SS48ES
Questions of how to design successful environmental management systems have motivated research in anthropology, political geography and international relations for decades. To the extent that ‘success’ depends on compliance, this raises a fundamental question: When and why do people comply with regulations governing the commons? I address this issue from a specific angle: Why do the same natural management policies fail in some spaces, while they succeed in others? Using the exemplifying case of fisheries management in Uganda, I argue that variance in compliance rates with state policies can be understood by studying the constitution and interaction of different lifeworlds and the effects of such encounters on the perceived cultural legitimacy of state policies in specific spaces. Existing studies suggest that if state-based lifeworlds are incongruent with local fisheries lifeworlds, the perceived cultural legitimacy of, as well as compliance rates with, government policies in these spaces are low.
|
Germany |
2017-02-21 |
2020-02-21 |
Social Science and Humanities |
|
Degree Award |
|
Priscilla Namaganda
ID: UNCST-2019-R001653
|
Oncogenic viral proteins associated with lymphomas at the Uganda Cancer Institute, Uganda, a comparison between HIV-associated and non-HIV-associated lymphomas.
REFNo: HS4342ES
To describe the oncogenic viral protein patterns among lymphomas at the Uganda Cancer Institute (UCI), comparing HIV-associated and non-HIV-associated lymphomas.,To determine the effect of oncogenic viral proteins on treatment outcomes of lymphoma among patients, HIV infected and uninfected at the UCI. ,
|
Uganda |
2024-11-13 17:04:50 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Robert Lukande
ID:
|
Post-Mortem Assessment of Pathogen and Anti-infective Distribution and Responses i HIV-Positive Patients
REFNo: HS24ES
• Use histopathology to determine pathogen (viral, fungal) distribution within and across tissue compartments\r\n• Improve diagnostic methods for HIV and AIDS-related infections\r\n• Determine distribution of anti-infective agents within and across tissue compartments\r\n
|
Uganda |
2016-12-13 |
2019-12-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
John Lule Ronald
ID:
|
Baseline Study for an Adolescent HIV and SRHR Programme
REFNo: HS23ES
The objective of this study is to establish baseline values and qualitative information on select project indicators. This information will serve as a basis for Alliance and CHAU to set targets and track changes and progress against these indicators throughout the project period. This information may also serve Alliance and CHAU to inform and shape programming as well as READY project contribution to Uganda national SRHR and HIV outcomes and targets.
|
Uganda |
2017-01-10 |
2020-01-10 |
Medical and Health Sciences |
|
Non-degree Award |
|
Lara Rosenoff Gauvin Shelley
ID:
|
We are Sons and Daughter of Bwoc: Refusal and Land Rights Protections in Rural Post-Conflict Acoliland, Northern Uganda.
REFNo: SS112ES
To understand: What do processes involved in writing a clan-based non-profit foundation’s constitution (in a previously oral tradition of indigenous governance) do for relatedness in the post-conflict, land-pressured context? After it is written, and circulated, what does the document do for relatedness in context? How does/can it mediate both between sons and daughters of the clan, and between clan members, National Government, and foreign companies, as examples? And finally, how do real and perceived land pressures impact ideas and practices of relatedness, and thus social repairing and particular notions of refusal, through time.
|
Canada |
2017-11-14 |
2020-11-14 |
Social Science and Humanities |
|
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
An Evaluation of the Association of Anaesthetists of Great Britain & Ireland Uganda Fellowship Programme.
REFNo: HS27ES
The research objectives are:\r\n\r\n1. To quantify the number of trained physician anaesthetists now working in Uganda, including their roles and responsibilities.\r\n\r\n2. To explore what impact the AAGBI Uganda Fellowship Programme has had on the standards of training in anaesthesia and patient care in Uganda.\r\n\r\n3. To explore how perceptions of the specialty of anaesthesia in Uganda have changed over the duration of the AAGBI Uganda Fellowship Programme.\r\n\r\n4. To understand the impact that different partnerships have had on the specialty of anaesthesia in Uganda over the last 10 years.\r\n
|
UK |
2016-12-13 |
2019-12-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
A cluster randomised trial to determine whether increased postoperative surveillance of adult African surgical patients reduces postoperative mortality
REFNo: HS298ES
Primary objective - To determine whether increased postoperative surveillance reduces in-hospital mortality in high-risk adult surgical patients aged 18 years and over in Africa.
Primary outcome measure - In-hospital mortality, censored at 30 days if the patient is still alive and in-hospital.
Secondary objective - To determine whether increased postoperative surveillance reduces the incidence of the composite of severe in-hospital complications and mortality in high-risk adult surgical patients aged 18 years and over in Africa.
Secondary outcome measure - Composite of severe in-hospital complications and mortality, censored at 30 days if the patient is still alive and in-hospital.
|
UK |
2019-04-16 |
2022-04-16 |
Medical and Health Sciences |
|
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
Family SuppleMented pAtient monitoRing afTEr suRgery (SMARTER) pilot trial
REFNo: HS944ES
To develop a training and support intervention, in accordance with the MRC complex intervention framework, to train family carers to perform and document basic vital signs, to supplement routine monitoring of patients by nursing staff, whilst they provide personal care to their relatives after surgery and to evaluate the effect of this intervention on frequency of documented vital signs for patients in the first three days after surgery in a stepped-wedge cluster trial.
To evaluate compliance with the trial intervention, and how this changes over the duration of the trial.
To evaluate the effect of the intervention on in-patient mortality, to inform the design of a subsequent international clinical trial across Africa
|
UK |
2021-03-23 |
2024-03-23 |
Medical and Health Sciences |
|
Degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
African Surgical Outcomes Study in Paediatric patients (ASOS-Paeds)
REFNo: HS2179ES
In paediatric surgical patients < 18 years in Africa: To determine the association between pre-operative, intra-operative and facility factors with postoperative complications and death. ,In paediatric surgical patients < 18 years in Africa: To determine the incidence of intraoperative severe critical incidents,,In paediatric surgical patients < 18 years in Africa: To determine the in-hospital postoperative mortality rate up to 30 days post-surgery,,To determine the incidence of in-hospital postoperative complications up to 30 days post-surgery in paediatric surgical patients <18 years in Africa,
|
UK |
2022-05-27 18:55:24 |
2025-05-27 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
The African Critical Illness Outcomes Study
REFNo: HS3338ES
To determine the availability of resources for essential emergency and critical in African hospitals.,To investigate the association between the provision of essential emergency and critical care to critically ill patients and mortality.,To estimate the proportion of critically ill patients who receive essential emergency and critical care.,To establish the mortality rate of the critically ill patients and those who are not critically ill.,To establish the proportion of adult (18 years or older) inpatients in African hospitals that are critically ill.,
|
UK |
2023-10-30 21:08:01 |
2026-10-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study.
REFNo: HS5389ES
To evaluate the impact of a structured antimicrobial review on rates of antimicrobial density, redundancy and associated indicators of antimicrobial utilisation.,To determine whether a structured antimicrobial review can be implemented in LMIC ICUs,
|
UK |
2025-01-31 7:20:18 |
2028-01-31 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
‘5 Rs to Rescue’ A quality improvement initiative with a cluster trial evaluation and embedded process evaluation
REFNo: HS5020ES
To evaluate the effect of the QI intervention on: 1. 30 day in-hospital mortality. 2. Duration of hospital stay.,To evaluate whether implementation of the ‘5 Rs to Rescue’ quality improvement intervention increases surveillance for patients at risk of ‘failure to rescue’ after surgery in hospitals in Africa.,
|
UK |
2025-01-22 12:30:25 |
2028-01-22 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adam Hewitt Smith
ID: UNCST-2019-R001658
|
Assessing the bottlenecks for coverage of Essential Emergency and Critical Care in Uganda, Tanzania, Ethiopia, and South Africa
REFNo: HS6924ES
To determine the underlying causes and suggested solutions of these bottlenecks.,To determine the implementation bottlenecks for the provision of EECC in public hospitals in Uganda, Tanzania, Ethiopia and South Africa ,To investigate the bottlenecks, and their underlying determinants, for the provision of EECC in hospitals in Uganda, Tanzania, Ethiopia and South Africa,
|
UK |
2026-01-19 13:39:06 |
2029-01-19 |
Medical and Health Sciences |
|
Non-degree Award |
|
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