Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
An education package to improve health worker communication with women and families after stillbirth or neonatal death: A feasibility study
REFNo: HS1102ES
1. To pilot an education package and associated resources, including train the trainer/training manuals and audio-visual aids to improve health worker communication in Malawi, Uganda, Zambia and Zimbabwe.
2. For feasibility
a. Explore the acceptability and implementation of the package with facility staff receiving training, trainers and service managers across settings.
b. Explore the acceptability and implementation of the package with undergraduate midwifery students receiving training.
c. Assess uptake and attendance/completion of the package.
d. Explore impacts of the research and education package on practice and clinical services.
3. To prepare for a full-scale evaluation:
a. Define the most appropriate primary and secondary outcomes to assess the effect of the educational package on health workers’ communication and parents’ experiences.
b. Assess the acceptability and burden of data collection for participants.
c. Use data to optimise the design and estimate the sample size for a full-scale trial.
d. Exploration of key resources associated with implementing the educational package will be completed to provide an economic understanding of the intervention and its potential impact.
e. To utilise existing and develop additional networks to identify potential sites for a full-scale trial.
4. To combine the feasibility, acceptability and uptake data to develop a full trial protocol by the end of the study.
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Uganda |
2021-04-21 |
2024-04-21 |
Medical and Health Sciences |
|
Non-degree Award |
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Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Translation and validation of the Perinatal Grief Intensity Scale in Kenya and Uganda
REFNo: HS2296ES
1. To perform a culturally sensitive translation and adaptation of the Perinatal Grief Intensity Scale in Kiswahili and Luganda
2. To assess validity and reliability via face, content and construct validity and internal consistency
3. To obtain statistical estimates pertaining to the use of the tool
|
Uganda |
2022-07-13 10:47:29 |
2025-07-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Development of a meta-core outcome set for stillbirth prevention and bereavement care following stillbirth
REFNo: HS2332ES
1) To identify a list of outcomes used in current stillbirth research together with outcomes reported in qualitative literature in an Low and Middle income Country (LMiC) setting relevant to stillbirth.
2) To prioritise outcomes from a health care professional, researcher and parent perspective from an LMic setting.
3) To integrate the outcomes important to all stakeholders in order to ratify a Core Outcome Set.
|
Uganda |
2022-08-25 12:09:48 |
2025-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
EVALUATING THE EFFECT OF A LOW-COST FOETAL HEART RATE MONITOR AND EDUCATIONAL PACKAGE ON MONITORING INTERVALS AND NEWBORN OUTCOMES IN GULU DISTRICT.
REFNo: HS2868ES
1. To assess the effect of a low-cost Foetal Heart Rate Monitoring device (Moyo) on the Foetal Heart Rate monitoring intervals.
2. To assess the effect of a low-cost FHRM device (Moyo) on detection of fetal heart rate abnormalities
3. To evaluate the effect of the intervention package on immediate newborn outcomes
4. To explore health care providers experiences of Foetal Heart Rate Monitoring before and after the intervention.
|
Uganda |
2023-07-06 17:16:36 |
2026-07-06 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Development and testing of a tool to assess health workers' clinical confidence to provide perinatal bereavement care in Sub-Saharan Africa (MAKSHSREC-2024-703)
REFNo: HS4959ES
To assess the validity and reliability of the tool across health workers providing care to parents in maternity facilities, including internal consistency and factor structure,
|
Uganda |
2024-10-21 15:14:14 |
2027-10-21 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Evaluation of a multicomponent intervention to improve perinatal bereavement support for women and families after stillbirth and neonatal death in Kenya and Uganda: A pragmatic cluster randomised controlled trial.
REFNo: HS3205ES
To explore factors influencing future scale up and sustainability of the intervention ,To explore potential mechanisms of impact of the intervention through understanding womens’, families’, health workers’ and service managers’ views and experiences of the intervention and usual care after stillbirth and neonatal death,To evaluate whether the intervention was implemented as intended during the trial by assessing fidelity, ‘dose’, reach and adaptations made in the study context. ,To assess the cost effectiveness of the intervention from the perspective of the local health systems in Kenya and Uganda ,To assess the mediating effect of perceived social support on intervention impact. ,To assess the impact of the intervention on maternal anxiety, risk of depression and development, diagnosis, and treatment of mental health conditions.,To assess the effectiveness of the co-produced multicomponent interventions in reducing perinatal grief intensity at 8-12 weeks post birth for women who have experienced stillbirth or early neonatal death. ,
|
Uganda |
2024-01-24 23:23:30 |
2027-01-24 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Experiences of the CEI members and Researchers working together during Global Health Research on Stillbirth Prevention and Bereavement Care: A grounded theory study in Sub-Saharan Africa and South Asia.
REFNo: SS4036ES
To produce an explanatory theory to underpin a working framework to support relevant research projects and programmes,To understand social processes that guide relationships between CEI members and researchers within a large global health programme,To understand researchers’ experiences of engaging with the CEI group within a large global health programme,To understand CEI group member experiences of contributing to research within a large global health programme,To gain better understanding of facilitators and barriers to effective community engagement through a grounded theory approach,
|
Uganda |
2025-08-18 13:51:30 |
2028-08-18 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Agnes Kiragga
ID:
|
Tracing non-rEtained HIV PoSitivE Pregnant Women enrolled in Option B+ and ascertaining their BabIeS outcomes (sTEPWISe)
REFNo: HS35ES
Specific Aim 1: Trace women, initiated ART under option B+ who disengaged from care and assess reasons for disengagement, as well as obtain corrected estimates of retention by evaluating the proportion of mothers who have re-engaged or died.\r\nSpecific Aim 2: Assess and compare HIV transmission rates among infants born to retained and disengaged mothers. \r\nSub-aim 2.1. Perform HIV DNA PCR testing on the infants of disengaged women \r\nSub-aim 2.2 Obtain HIV status data on infants of retained women from existing medical records, or by providing HIV DNA-PCR testing for untested-infants or those whose test was performed within the previous month.\r\nSpecific Aim 3: To measure efavirenz (EFV) levels in the blood collected from all re-engaged and a matched sample of retained women. \r\nSpecific Aim 4: To perform genotypic testing among retained and disengaged women with virologic failure defined as viral load ≥1,000 copies/ml in order to describe mutations that are known to confer drug resistance. \r\n
|
Uganda |
2017-05-05 |
2020-05-05 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
Men at Gaming Centers: Point of Care HIV and STI Testing
REFNo: HS70ES
• To test the acceptability and feasibility of same day testing of HIV and syphilis testing, test result notification, prevalence of HIV and syphilis, and proportion linked to care among men attending at gaming/betting centers
• To identify the proportion of men involved in other self-reported risky behaviors such as hazardous alcohol intake, illicit drug use, having sex with men and having multiple sexual partners,
• To test the diagnostic performance of the ChemBio duo HIV-syphilis point of care test.
|
Uganda |
2017-05-30 |
2020-05-30 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
Locating disengaged HIV positive women on Option B+ and ascertainment of outcomes among their infants
REFNo: HS175ES
1. To describe the pregnancy outcomes and HIV care status among women (and their exposed infants) who initiate Option B+
2. To correct 6 week and 18 month estimates of MTCT through tracing of a random sample of HIV positive women who initiated Option B+ during pregnancy and disengaged from care.
3. To identify factors associated with HIV sero-positivity among infants born to women initiated on Option B+.
4. To establish the frequency of Multiclass Resistance among HIV positive infants born to women initiated on Option B+
5. To estimate the proportion of disengaged women with viral failure and correct estimates of viral suppression (3 rd UN 90 goal) in the facilities.
|
Uganda |
2018-04-04 |
2021-04-04 |
Medical and Health Sciences |
|
Non-degree Award |
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Agnes Kiragga
ID:
|
A Pilot Test of a Technology-delivered HIV Self-Testing Intervention in Kampala, Uganda
REFNo: HS307ES
1) An established 24-hour call-in center staffed by medical providers who will deliver accurate HIV/STI information, perform pre- and post-test counselling, assist with conducting HIVST and interpreting the HIVST results, and referral and linkage to appropriate post-test prevention and treatment care; and
2) The use of SMS and social media streams – specifically private Facebook and Twitter messages - to “push†theoretically-grounded messages that promote HIVST and provide additional private communication routes between participants and medical provider research staff. The study aims are:
Aim 1: Develop HIVST messages and finalize study procedures and materials with input from a Community Advisory Board (CAB), and beta test the intervention with 6 sexually active Ugandan adults (18-49 years old; 50% female).
Aim 2: Using a pre-post design, assess the feasibility, acceptability and preliminary impact of the HIVST intervention developed in Aim 1 for Ugandan adults (n=100; 70% 18-24 years old, 30% 25-49 years old; 50% female). Feasibility will be assessed by whether enrollment targets are reached and the proportion of completed 1- and 3-month follow-ups calls. Acceptability items will be gathered at 1- and 3-month assessments. Preliminary impact will be determined by the percentage of participants who perform HIVST in the 3 months after enrollment.
Aim 3: Analyze process indicators of the overall use of the HIVST intervention, including the number of HIVST kits requested, the volume of callers requesting HIVST during the study period, the number of persons calling for assistance with self-testing procedures, the number of post-test counseling calls received, and the number of persons linked to follow-up prevention and care services.
|
Uganda |
2019-02-26 |
2022-02-26 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
Reproductive Health Empowerment through Telehealth
REFNo: HS425ES
1-With input from a Community Advisory Board develop a user-centered mobile-based reproductive health content targeted for men through SMS, interactive voice response.
2-Assess the feasibility and acceptability of the Men’s Telehealth Information Package (mTIP) on uptake of family planning and reproductive health services.
3-Assess the men’s knowledge and attitudes towards family planning following receipt of the Men’s Telehealth Information Package (mTIP)
4-Assess uptake of and attitudes towards FP and couple communication among women whose spouses received the Men’s Telehealth Information Package (mTIP) intervention.
|
Uganda |
2019-08-06 |
2022-08-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
Community Pharmacies for Assessing STI Prevalence using Point of Care diagnostics study (COPHAS)
REFNo: HS1274ES
Aim 1: To estimate the prevalence of curable STIs and HIV among persons accessing health services at community pharmacies in Kampala and Wakiso Districts.
Aim 2: To determine the feasibility and uptake of pharmacy-based specimen collection and POC testing for curable STIs and HIV among persons seeking health care services at community pharmacies in Kampala and Wakiso Districts. Uptake will be measured among the three groups of persons i.e. Persons seeking EC (group 1), clients with STI symptoms (group 2) and persons without STI symptoms (group 3)
Secondary quantitative aims:
Aim 3: To determine treatment completion among persons diagnosed with an STI at the community pharmacies in Kampala and Wakiso Districts.
Aim 4: To determine linkage to care and ART initiation among newly diagnosed HIV positive persons at the community pharmacies in Kampala and Wakiso Districts.
Aim 5: To determine the baseline and 3-month knowledge about STI and STI treatment guidelines, and principles of antimicrobial stewardship of pharmacy staff. In addition, to assess the acceptability of POC STI diagnostics collocated with the pharmacy, to pharmacy owners and staff.
Qualitative aims
Aim 6: To assess the acceptability and client satisfaction of STI and HIV testing at community pharmacies in Kampala and Wakiso Districts.
Partner notification sub-study
Aim 7: To determine the effect of technology-supported partner notification and treatment initiation using Call for LifeTM technology among persons diagnosed with an STI or HIV at community pharmacies.
|
Uganda |
2021-03-26 |
2024-03-26 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
Piloting a HIV Risk assessment application to increase awareness and uptake of HIV prevention services among young adults in Uganda. (SIDARISK)
REFNo: HS1293ES
• To assess the extent of high-risk sexual behavior and related practices among young adults using a web-based individualized HIV risk platform (SIDARISK)
• To establish the feasibility of using an existing telehealth platform for the referral and linkage to HIV/STI testing and prevention services following risk assessment by the SIDARISK application.
• To understand acceptability of the SIDARISK application for HIV risk assessment among young adults in Uganda
• To establish the feasibility of using a telehealth platform for provision of information on HIV risk reduction and linkage to HIV and PrEP services following using of the SIDARISK application
|
Uganda |
2021-03-18 |
2024-03-18 |
Medical and Health Sciences |
|
Non-degree Award |
|
Agnes Kiragga
ID:
|
SARS-CoV-2 international biorepository and diagnostic test performance
REFNo: HS1808ES
Primary:
• To create a biorepository to test retrospectively the performance of investigational, emerging diagnostic technologies in the intended population or setting compared to a reference comparator for diagnosing SARS-CoV-2 infection using frozen samples.
Secondary
• To test prospectively the accuracy of investigational, emerging diagnostic technologies in the intended population or setting compared to a standard comparator for diagnosing SARS-CoV-2 infection
• To determine agreement between self-collected nasal swabs, saliva and clinician-collected nasopharyngeal swab samples for the diagnosis of SARS-CoV-2 using a reference test in Uganda.
• Determine the proportion of non-reportable results (unresolved, indeterminate and incomplete) and turn-around time compared to reference test.
• To assess acceptability of self-collected nasal swab tests and saliva for testing SARS-CoV-2 in both participants and healthcare workers in Uganda.
• To explore socio-demographic, behavioural and clinical factors associated with positive SARS-CoV-2 diagnosis.
|
Uganda |
2022-05-13 7:45:44 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Tatiana Morais
ID:
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"Women’s Talkâ€
REFNo: SS173ES
The main objective of this research project is to understand the camps’ context response to Gender-Based Violence (GBV). The focus will be on what the refugee considers to be the best practices already implemented and what can be improved. Also, Uganda does have a National GBV Database (NGBVD) which makes the country a pioneer in addressing and making visible GBV, thus, this research would like to learn from the Uganda good practices and policies.
|
Portugal |
2018-06-26 |
2021-06-26 |
Social Science and Humanities |
|
Non-degree Award |
|
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
|
PREDICTORS OF COGNITIVE IMPAIRMENT AMONG PATIENTS WITH FIRST EPISODE PSYCHOSIS IN UGANDA.
REFNo: HS88ES
i) To determine the genetic (COMT, DISC1, HT2RA, BDNF) and environmental (substance use and childhood trauma) factors associated with cognitive impairment among patients with a psychotic episode for the first time.
ii) To determine the frequency of BDNF gene polymorphism and its association with serum BDNF levels and cognitive impairment among patients with a psychotic episode for the first time.
|
Uganda |
2017-09-20 |
2020-09-20 |
Medical and Health Sciences |
|
Non-degree Award |
|
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
|
COGNITIVE IMPAIRMENT AMONG PATIENTS WITH A FIRST EPISODE OF PSYCHOSIS IN UGANDA: ASSESSMENT, RISK PROFILE AND IMPACT ON QUALITY OF LIFE.
REFNo: HS142ES
1. To review the evidence on the assessment of cognitive function using brief neuropsychological tests in patients with FEP in sub Saharan Africa.
2. To determine the validity of cognitive assessments delivered using a smart phone application in patients with FEP in Uganda.
3. To determine mean duration and factors associated with resolution of psychotic symptoms among patients with FEP in Uganda.
4. To determine the association between genetic and environmental factors (childhood trauma and DUP), and the development of CI in patients with FEP in Uganda.
5. To determine the association between impairment in specific cognitive domains and quality of life in patients with FEP in Uganda.
|
Uganda |
2019-01-08 |
2022-01-08 |
Medical and Health Sciences |
|
Degree Award |
|
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
|
PREVALENCE, CORRELATES AND EXPLANATIONS OF A LONG DURATION OF UNTREATED PSYCHOSIS AMONG ANTIPSYCHOTIC NAÃVE PATIENTS AT BUTABIKA HOSPITAL: A MIXED METHODS STUDY.
REFNo: HS237ES
1. To determine the prevalence and factors associated with a long duration of untreated psychosis among patients with a first episode psychosis at Butabika hospital in Uganda.
2. Achieve a qualitative understanding of influence of prior treatment with alternative and complimentary therapies on duration of untreated psychosis among patients with a first episode of psychosis (FEP) presenting to Butabika hospital in Uganda.
|
Uganda |
2019-01-29 |
2022-01-29 |
Medical and Health Sciences |
|
Non-degree Award |
|
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
|
Leveraging Digitization, Archiving and Artificial Intelligence Applications to Utilize Patient Charts for Research: A Pilot Study Examining Predictors of Sustained Mental Health Care Engagement in Ugandan Psychosis Patients
REFNo: HS6912ES
4. To develop processes to scale methods for converting patient clinical files to standardized datasets for mental health research.,3. Re-examine predictors of sustained mental healthcare engagement in 1,677 Ugandan psychosis patients enrolled for the first time at Butabika Hospital in 2018.,2. Transform patient charts of Ugandan psychosis patients enrolled at Butabika Hospital in 2018 into a standard anonymized longitudinal database ,1. To leverage digitization, archiving and artificial intelligence applications to integrate patient clinical files into an existing electronic medical record at Butabika National Referral Mental Hospital.,Leveraging Digitization, Archiving and Artificial Intelligence Applications to Utilize Patient Charts for Research.,
|
Uganda |
2026-04-29 15:15:20 |
2029-04-29 |
Medical and Health Sciences |
|
Non-degree Award |
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