Kate Scow
ID:
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Innovations  in Dry Season Horticulture for Women and Smallholders in East Africa -Production and Marketing for income, nutrition, and climate resilience
REFNo: A14ES
Dry season vegetable production has been identified as a high priority in the largely rainfed (>97%) agricultural systems of Uganda. Off season vegetable supplies are currently inadequate to meet human nutritional needs. As rainfall patterns become increasingly unpredictable and rapid population expansion places more pressure on food systems, demand for vegetables will further outstrip supplies. This spin-off project builds on the team’s previous participatory work in Uganda to convene stakeholders from public and private sectors and develop innovations in small scale dry season vegetable production for women farmers in East Africa. We will develop a research and development approach resulting in release of horticulture irrigation innovations tested at five ‘innovation sites’ over three field seasons in Eastern Uganda and create a framework for local public and private sector organizations to develop small scale irrigation systems. We will work closely with smallholder women farmers who are often excluded from irrigation and marketing developments. We will: i) work at five locations over three dry seasons to test dry season vegetable production systems with farmers, research partners, district staff, NGO partners, and university students, ii) assess agronomic, economic, market, nutrition, and gender impacts of the innovations; and iii) develop scale-out options for the most promising technologies. Ugandan partners include two regional NGOs, three institutes of the National Agricultural Research Organization, and one university. Development of a co-innovation systematic approach for assessing and supporting innovations in dry season vegetable production will strengthen small scale farmer enterprises targeted to local markets and family consumption.
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USA |
2017-10-31 |
2020-10-31 |
Agricultural Sciences |
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Non-degree Award |
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marie nanyanzi
ID: UNCST-2019-R001553
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Point Of Entry Sauti Za Wananchi (Voices of the citizens)Extension Survey
REFNo: SS468ES
To understand the COVID-19 effects on the citizens’ experience and key services they receive during this era of COVID-19 especially
â–ª Establish citizen access to safe water;
â–ª Establish citizen access and usage of health services and knowledge, Attitudes and
Practices (KAPs);
â–ª Find out level of participation/involvement/interaction in development and public
activities /institutions;
â–ª Find out access and usage of financial services amongst citizens;
â–ª Find out how; what and when citizen access different type of information including
government and development information.
â–ª Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different
guidelines, policies; laws and regulations etc
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Uganda |
2020-09-28 |
2023-09-28 |
Social Science and Humanities |
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Non-degree Award |
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marie nanyanzi
ID: UNCST-2019-R001553
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Sauti Za Wananchi (Voices of citizens) Baseline Survey Panel II
REFNo: SS887ES
o Gather opinions from the citizens on the key services they receive especially
 Establish citizen access to safe water;
 Establish citizen access and usage of health services;
 Establish the citizens attitudes and practices on issues related to COVID-19
 Find out level of participation/involvement/interaction in development and public activities /institutions;
 Find out access and usage of financial services amongst citizens;
 Find out how; what and when citizen access different type of information including government and development information.
 Establish the knowledge, Attitudes and Practices (KAPs) of citizens on different policies; laws and regulations etc
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Uganda |
2021-07-05 |
2024-07-05 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Madelyn Prevost
ID:
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The Entrepreneurial Spirit: Crafting subjects with regimented health and religion
REFNo: SS122ES
This project is intended to further the knowledge on HIV/AIDS, Catholicism, Non-Governmental Organizations, poverty, and work in a Ugandan context as globalization, greater access to medicine, and modernity change the cultural landscape. In addition to furthering scholarly knowledge, this project will also, ideally, help the site organization, Reach Out Mbuya remain relevant in the changing climates of donor funding, client needs, and HIV prevalence rates. Reach Out is a Catholic-based HIV/AIDS organization that seeks to provide holistic care to clients and their families through medical care, material support, subsistence projects, counseling, HIV prevention, and peer support. In Kampala, Reach Out has community sites in Mbuya, Banda, and Kinawatak; they also have an additional site in Kasaala. I will likely draw all of my participants from the Mbuya, Banda, and Kinawataka site locations; as a volunteer, I will spend most days at Mbuya, but also do work in Banda and Kinawataka sites weekly. Therefore, I will be more known to staff and clients at these locations, making recruiting participants smoother.
Building off literature that demonstrates how an HIV diagnoses affects a person’s sense of self and habits (Wekesa and Coast [2013]; McGrath et al [2014]); Whyte [2014]; Bartos and MacDonald [2000]), I propose that HIV, as well as comprehensive aid programs can have unique and varied affects on a person’s employment and livelihood. Adding to this argument, I will draw on literature dealing with subject formation (how a person’s identity and behaviours are formed and changed through processes and interactions), both in secular and Christian contexts (Foucault [2000]; Koopman [2013]; Skinner [2012]; Tambling [1990]; Norget, Napolitano, and Mayblin [2017]). Using this literature, I will argue that it is a combination of the regimented HIV/AIDS treatment schedule and Catholic belief and practice encouraged and facilitated by Reach Out that creates a socially responsible and productive subjects in their clients.
Working from this hypothesis, my project asks three primary questions: (1) How might being HIV positive affect an individual’s work, livelihood, and/or employment, and what role might religion play in the extent of these effects? (2) How does Reach Out’s comprehensive, holistic-based approach complement services provided by the government? (3) How does being HIV positive affect one’s social and/or economic standing, and one’s capability to remain in care?
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Canada |
2017-11-20 |
2020-11-20 |
Social Science and Humanities |
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Degree Award |
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Joshua Nfambi
ID:
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Effect of Moringa oleifera extracts on the HIV model: A study of nutrient bioavailability and immunological responses
REFNo: HS46ES
1. To assess the presence and quantity of micronutrients in Moringa oleifera leaf extracts
2. To determine the bioavailability of the micronutrients in Moringa oleifera in a Murine model
3. To establish the effect of Moringa oleifera leaf extracts on HIV virus replication in T-lymphocytes and macrophages
4. To determine the effect of Moringa oleifera leaf extracts on secretion of chemokines, IL1, 12 TNF α and INF γ in HIV infected cells
5. To determine the effect of Moringa oleifera leaf extracts on the cell mediated immune system of a humanized HIV murine model
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Uganda |
2017-04-25 |
2020-04-25 |
Medical and Health Sciences |
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Non-degree Award |
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Bruno Braak Jim
ID:
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Access to land and justice among South Sudanese refugees in Uganda
REFNo: SS67ES
This proposed research would contribute to my PhD dissertation. It would draw on a prior period of three months of intensive and collaborative field research in South Sudan as a basis to compare current perceptions and practices with. The objective of this proposed research would be to discover the changes and continuities in Western Equatorians’ access to land and justice mechanisms. Doing so, it hopes to shed light on the impact of the process of forced displacement to Uganda. Conceptually, this research would draw on notions and practices around authority, identity and property. Special attention will be devoted to the differentiated impact according to gender, ethnicity, and socio-economic background.
|
Netherlands |
2017-05-09 |
2020-05-09 |
Social Science and Humanities |
|
Degree Award |
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Lucia Rost Aline
ID:
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Negotiating time use: an inter-generational mixed methods approach to intra-household decision-making on care and domestic work in Northern Uganda
REFNo: SS59ES
My research develops an intergenerational approach to understanding intra-household decision-making on time use, especially with regards to time spent on care work—in the post-conflict setting in Northern Uganda.
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Germany |
2017-06-13 |
2020-06-13 |
Social Science and Humanities |
|
Degree Award |
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Mahsa Abassi
ID:
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Utilization of SMS Messaging Services to Improve Retention in Care of HIV-Infected Individuals in Uganda Short Title: SMS-2-Retain (S2R)
REFNo: SS62ES
The objective of the study is to determine if mobile health (mHealth) technology (text/voice-messaging services) is an effective method of improving retention in care for newly diagnosed HIV-infected individuals enrolling into care, as compared to standard of care. This is a pilot, non-blinded, randomized trial of mobile health implementation into routine HIV care. This pilot trial will be focusing on 1) two-week retention in care of all HIV-infected participants from enrollment and followed by 2) participants who have been found to have cryptococcal antigenemia, a population of participants most at risk for early morbidity and mortality.
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USA |
2017-03-07 |
2020-03-07 |
Social Science and Humanities |
|
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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Automated visual evaluation and geospatial mapping for cervical cancer screening optimization in sub-Saharan Africa (AVE-Map)
REFNo: HS2069ES
3. To use AVE and geospatial analysis to scale up cervical cancer screening in Uganda ,2. To determine access to cervical cancer screening and referral pathways in Uganda ,1. To validate and expand use of AVE for cervical cancer screening in SSA ,We aim to leverage and develop data science expertise at our sites to first optimize and then combine AVE-based screening by health workers at peripheral health facilities with geospatial-analysis and needs-driven assessment to inform scale-up of cervical cancer screening in Uganda ,
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Uganda |
2022-02-28 |
2025-02-28 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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Smart Discharges for Mom & Baby: A cohort study to develop prognostic algorithms for post-discharge readmission and mortality among mother-infant dyads..
REFNo: HS2174ES
To identify gaps and opportunities during in-hospital, discharge, and post-discharge care to inform the future development of an evidence-and risk-based bundle of interventions to improve postnatal care (PNC) for dyads.,To inform the development of an integrated maternal and newborn risk-based post-discharge care program.,To develop and internally validate clinical risk prediction models for identifying dyads at high-risk of death or hospital readmission in the 6 week post-delivery post-discharge period.,
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Uganda |
2022-04-07 |
2025-04-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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Development of Software to Rapidly Assess Placenta Images at Birth
REFNo: HS3159ES
1. To develop AI-based software that accurately identifies a range of placental features and diagnoses from digital images.
2. To improve the reliability and robustness of the software under different conditions (e.g., different cameras, lighting).
3: To test and quantify improvements in software accuracy with medical data input (e.g., infant sex, delivery mode, and birth weight).
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Uganda |
2023-12-21 20:48:48 |
2026-12-21 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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OPTIMIZATION, VALIDATION AND ASSESSMENT OF FEASIBILITY AND ACCEPTABILITY OF HPV TESTING USING CODA
REFNo: HS4734ES
To develop and establish a novel rapid multi-modal algorithm (CANOPY) for screening and treatment of cervical cancer integrating multiple (CODA, VIA, ML) screening modalities to improve diagnostic yield. ,To gather design feedback to improve CODA workflow and device design, and refine CODA device, assay, and workflow using this critical feedback provided by Ugandan stakeholders,To evaluate the feasibility and acceptability of CODA in a clinical setting in Uganda based on feedback from clinical, public health, and patient stakeholders,To evaluate HPV testing using CODA in comparison to other (VIA, ML, ATILA System) devices for clinicians and patients engaged in community-based cervical cancer screening. ,To determine the diagnostic accuracy of CODA a clinical setting, using FP rate and comparison with gold-standard HPV tests and cytology,We will optimize, validate and assess the feasibility and acceptability of HPV testing using CODA and develop and validate a multimodal cervical cancer screening algorithm to optimize diagnostic yield (CANOPY).,
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Uganda |
2024-12-10 15:49:00 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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PACO Heart Evaluation and Risk Tracking (PACO-HEART)
REFNo: HS5985ES
Main objective: 1. Determine whether women with HIV taking DTG during pregnancy are more likely to experience hypertension, have elevated cardiovascular disease risk factors, and demonstrate vascular dysfunction postpartum.
Sub-Objectives:
1. Prospectively assess postpartum cardiovascular disease risk factors in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
2. Assess vascular function in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
3. Quantify and compare biomarkers of cardiovascular disease in peripheral plasma in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
4. Examine association between placenta pathological features (already measured in PACO cohort participants) and postpartum hypertension, vascular function, and biomarkers of cardiovascular disease
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Uganda |
2025-09-17 13:26:00 |
2028-09-17 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Polycyclic aromatic hydrocarbon exposures and dietary risk of Esophageal squamous cell cancer in southwestern Uganda
REFNo: HS37ES
1) To evaluate biomass fuel exposure as an ESCC risk factor by comparing personal carbon monoxide exposure among ESCC patients to that of age and gender matched controls with normal esophageal epithelia. We hypothesize that individuals with ESCC have greater exposure to biomass fuel compared to matched age and gender controls. \r\n\r\n2) To assess food preparation methods and dietary patterns as risk factors for ESCC in southwestern Uganda. We hypothesize that patients with ESCC have unique food preparation methods and consumed foods with high polycyclic aromatic hydrocarbons content compared with age and gender-matched controls with normal esophageal epithelia.\r\n
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Uganda |
2017-03-28 |
2020-03-28 |
Medical and Health Sciences |
|
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Impact of HIV-infection on Geriatric Health among Older-Age People in Southwestern Uganda.
REFNo: HS97ES
Our main objective for this study is to provide data to help answer the following question:
How does the prevalence of and risk factors for frailty, decreased physical functioning, visual/auditory impairment, and neurocognitive disorders differ between HIV-infected people versus HIV-uninfected controls in Uganda.
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Uganda |
2017-11-08 |
2020-11-08 |
Medical and Health Sciences |
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Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Epidemiology of Coronary Artery Disease among People with HIV in Rural sub-Saharan Africa
REFNo: HS267ES
Our over-arching goals are to demonstrate the extent to which coronary artery disease (CAD) burden may be greater among PLWH in rural Uganda, to discern which risk factors are responsible for this greater burden, and to propose a risk score and promising intervention targets to improve the health of this population.
Aim 1: Determine whether CAD is more prevalent and severe among PLWH than HIV-uninfected comparators in rural Uganda. We will complete coronary CT angiography in 600 participants and compare the prevalence and severity of CAD between PLWH and HIV uninfected comparators, before and after adjustment for traditional risk factors
Aim 2: Determine the extent to which the association between HIV infection and CAD is modified by sex and region. Within our cohort, we will test for effect modification by sex
Aim 3: Identify regional correlates of CAD, and develop a risk prediction score for the presence of CAD among PLWH in rural sub-Saharan Africa. We will collect data on traditional (e.g. age, smoking, diabetes), HIV-specific (e.g. macrophage activation, CD4 count, ART history), and region-specific factors (e.g. biomass exposure, K:T ratio, tuberculosis infection). In Aim 3a we will include traditional, HIV-specific and regional risk factors in models to identify correlates of CAD. In Aim 3b, we will propose a simplified risk score to identify PLWH with CAD.
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Uganda |
2019-01-29 |
2022-01-29 |
Medical and Health Sciences |
|
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Experiences and Perspectives of Patients with Hypertension in Mbarara, Uganda
REFNo: HS343ES
To understand the patient experience of hypertension, including diagnosis, understanding of disease, medical adherence, and treatment regimens.
|
Uganda |
2019-06-06 |
2022-06-06 |
Medical and Health Sciences |
|
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Cardiovascular risk factor profiles and outcomes in rural Uganda: The Bugoye Hypertension Improvement Project (B-HIP)
REFNo: HS487ES
1. To assess the baseline (at time of enrollment to BHIP) prevalence of various cardiovascular risk factors (obesity, dyslipidemia, and diabetes mellitus) in adults visiting the Bugoye Hypertension Improvement Project.
2. To determine incidence of sustained blood pressure control among persons with hypertension enrolled in BHIP.
3. To assess the costs of hypertension care in a Level III healthcare center in rural Uganda.
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Uganda |
2020-02-07 |
2023-02-07 |
Medical and Health Sciences |
|
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Epidemiology of cardiac dysfunction in sub-Saharan Africa: Heart Failure Registry of HIV-infected and HIV-uninfected persons in Uganda and Zambia
REFNo: HS788ES
1. To describe the clinical characteristics, treatment outcomes, and predictors of all-cause and CV mortality among HIV-infected and HIV-uninfected heart failure adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
2. To describe echocardiographic etiology of heart failure among HIV-infected and uninfected adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
3. To determine the differences in the serum markers of cardiac fibrosis, cardiac injury, oxidative stress, and hypercoagulability in HIV-infected and HIV-uninfected individuals hospitalized with heart failure at Mbarara Regional Referral Hospital and the University of Zambia Hospital.
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Uganda |
2022-03-30 |
2025-03-30 |
Medical and Health Sciences |
|
Non-degree Award |
|
Samson Okello
ID: UNCST-2019-R001580
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EsophaCap for the Detection of Early Esophageal Carcinoma
REFNo: HS3248ES
Using our POC approach to carry out a diagnostic pilot study of ESCC in Uganda,In order to achieve fully automatic high-speed biomarker assaying, to design a small,light apparatus,In order to achieve a sample-to-answer assay, to implement DNA extraction, bisulfitetreatment, and methylation-specific PCR into a magnetofluidic chip with dried reagents.,Using a sponge-capsule swallowed/tethered collection device, to construct amethylation marker-based strategy to detect ESCC,To evaluate and validate the performance of the combined sponge methylation biomarker strategy in vivo in PRoBE-compliant, among prospective live cohorts od patients with EAC/HGD, ESCC and gastric cancer and controls in Uganda.,
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Uganda |
2024-04-26 9:27:48 |
2027-04-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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