Stephen Okoboi
ID: UNCST-2019-R001356
|
Controlled Trial of Game Changers: A Group Intervention
to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES
1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
|
Uganda |
2021-11-30 |
2024-11-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Anti-Retroviral Therapy Adherence Measurement Methods and Virological Failure in HIV infected Ugandans on long-term ART
REFNo: HS1949ES
1a. To describe incidence of virological failure in patients enrolled in the long-term ART cohort and assess the relationship between adherence to antiretroviral therapy (ART) measured either by patient self-report, appointment keeping and pill count and having virologic failure among HIV-infected Ugandan adults receiving long-term first line.
1b. To examine overall adherence measurement methods as a predictive test for VF among long term ART patients using a case control design taking patients confirmed with VF as cases and use incidence density sampling to sample for controls matched with time and age.
2. Determine the barriers and facilitators of ART adherence among patients on long-term ART at adult Infectious Diseases Institute (IDI) ART clinic using the Theoretical-Domains-Framework with 16 semi-structured, in-depth interviews with both people experiencing VF and those without VF, and ART providers (Medical Officers, Nurses, and counsellors)
|
Uganda |
2021-12-15 |
2024-12-15 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Peer Delivered HIV/Syphilis Self-Testing with Assisted Partner Notification Services for Men who Have Sex with Men (MSM) in Uganda
REFNo: HS3021ES
Estimate the cost-effectiveness of peer-delivered HIV/syphilis self-tests and partner services compared to facility-based testing.,Conduct a pilot randomized trial to pilot test the preliminary effectiveness of peer delivered HIV/syphilis self-tests and partner services versus facility-based testing., Conduct formative research to inform implementation of peer delivered self-tests for HIV and syphilis with partner services for Ugandan MSM. ,
|
Uganda |
2023-10-31 19:59:00 |
2026-10-31 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
UNDERSTANDING DRIVERS OF TB AND MALARIA PREVALENCE AND INCIDENCE, AND BARRIERS TO UPTAKE OF HEALTH SERVICES AND RETENTION IN CARE – COMMUNITY VOICE PERSPECTIVE IN NAMAYINGO DISTRICT
REFNo: SS2915ES
To collaboratively develop recommendations for driving sustainable impact and improving health outcomes in the context of TB and malaria.,To identify community-specific needs and gaps in current TB and malaria interventions and healthcare delivery systems.,To explore the socio-economic, cultural, and behavioral factors influencing the spread and persistence of TB and malaria within communities.,To engage directly with community members to understand their perspectives on the barriers and drivers of TB and malaria prevalence and incidence.,To understand the drivers of TB and malaria prevalence and incidence, as well as barriers to the uptake of health services and retention in care from a community voice perspective in Namayingo district,
|
Uganda |
2024-07-26 15:43:11 |
2027-07-26 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Stephen Okoboi
ID: UNCST-2019-R001356
|
Amplifying Community Voices and Lived Experience of the Perceived Impact of Climate Change on Health among Community Health Workers in Namayingo District, Uganda
REFNo: SS4546ES
1.Document CHW experiences of the intersection between climate change and health among individuals, families, and communities.
2.Assess CHW experiences of how climate change affects their role and the health system more broadly.
3.Describe CHW perspectives on community strength and resilience in the face of the climate crisis, including local solutions.
4.Explore CHW recommendations for developing a climate-informed health workforce and climate-resilient health systems and communities.
|
Uganda |
2025-11-04 13:34:31 |
2028-11-04 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Denish Calmax Angol
ID:
|
Antibacterial Use and Resistance in Under Five Children in Post Conflict Northern Uganda
REFNo: HS362ES
General study objective
•To assess the burden, drivers of inappropriate antibacterial prescriptions and resistance patterns of the pathogens among under five children attending care in selected public health facilities in Lango sub-region, northern Uganda.
Specific objectives
•To determine microbiologically, the burden and drivers of inappropriate prescription of antibacterials for under 5-year outpatient children presenting with acute diarrhoea at public health facilities in Lango sub-region (Sub-study I)
•To determine microbiologically, the burden and drivers of inappropriate prescription of antibacterials for under 5-year outpatient children presenting with UTRIs at public health facilities in Lango sub-region (Sub-study II)
•To determine the proportion of bacterial species and their resistance among under 5 year inpatient children with systemic infections at Lira Regional Referral Hospital (Sub-study III)
•To determine the prescribers’ knowledge, attitudes and practices regarding antibacterial prescription with respect to the available guidelines for under 5-year outpatient children with acute diarrhoea and URTIs at public health facilities in Lango sub-region (Sub-study IV)
|
Uganda |
2019-11-19 |
2022-11-19 |
Medical and Health Sciences |
|
Degree Award |
|
Robert Kairania
ID:
|
Reassessing the HIV and STI syndemic in Rakai, Uganda after scale-up of combination HIV prevention interventions: a population-based study
REFNo: HS364ES
Aim 1: To measure population-level prevalence of syphilis, Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), and herpes simplex virus 2 (HSV-2) among ~2000 RCCS participants aged 18-49.
Aim 2: To assess the prevalence of antimicrobial resistant mutations among individuals with PCR-confirmed gonococcal infection
Aim 3: To assess the association between individual-level and partner use of CHIs and STI prevalence.
|
Uganda |
2019-06-06 |
2022-06-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Robert Kairania
ID:
|
TESTING HIV SUSCEPTIBILITY IN FORESKIN TISSUE
REFNo: HS372ES
Study objective: To explore potential determinants of HIV infection in foreskin tissue.
Aim 1: Explore host immune factors that contribute in vitro HIV infection.
Aim 2: Explore microbial factors that contribute in vitro HIV infection.
Aim 3: Explore viral factors that contribute in vitro HIV infection
|
Uganda |
2019-08-06 |
2022-08-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Robert Kairania
ID:
|
Baseline, Midterm and End of Project Evaluation Protocol for Masaka Regional mechanism
REFNo: SS334ES
The purpose of the evaluation is to collect data that will inform improvement of program implementation so that services are provided more effectively and efficiently in the region and best practices shared with other IPs in the country. The evaluation will also inform RHSP, CDC and other stakeholders about program challenges, performance gaps, progress towards achievement of set targets and program outcomes (effectiveness) in a timely manner so that implementation strategies can be maintained, scaled up or modified where necessary.
|
Uganda |
2019-10-07 |
2022-10-07 |
Social Science and Humanities |
|
Non-degree Award |
|
Robert Kairania
ID:
|
HIV DISCLOSURE TRAJECTORIES AND ADHERENCE TO ANTIRETROVIRAL THERAPY AMONG CHILDREN IN MASAKA REGION, UGANDA.
REFNo: HS522ES
i. To assess the association between disclosure of HIV diagnosis and ART adherence among children on ART
ii. To examine the socio-cultural factors that influence disclosure of HIV diagnosis among children on ART
iii. To explore lived experiences before, during and after disclosure of HIV diagnosis among children on ART
|
Uganda |
2020-02-11 |
2023-02-11 |
Medical and Health Sciences |
|
Degree Award |
|
Robert Kairania
ID:
|
Exploration of psychological distress and cross-cultural adaptation of a mental health measure for people living with HIV in Rakai, Uganda
REFNo: SS408ES
Aim 1: To characterize local manifestations of psychological distress among people living with HIV in rural communities in Rakai, Uganda
Aim 2: To identify and cross-culturally adapt appropriate mental health measurement instruments based on findings from Aim 1.
Aim 3: To validate the adapted mental health measurement instrument within the rural Rakai population.
|
Uganda |
2020-02-21 |
2023-02-21 |
Social Science and Humanities |
|
Non-degree Award |
|
Robert Kairania
ID:
|
Performance of the Asanteâ„¢ HIV-1 Rapid Recencyâ„¢ Assay in recent HIV infections detection and incidence estimation in a Ugandan setting using the Rakai Community Cohort Study
REFNo: HS534ES
Main aim: To determine the performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of HIV-1 recent infections and incidence estimation in a Ugandan setting with A and D predominant subtypes.
Specific aims
I. To evaluate the diagnostic performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of recent infections in a setting with A and D predominant subtypes.
II. To establish the false recency rate (FRR) of the Asanté™ HIV-1 Rapid Recency™ assay.
III. To determine factors associated with being misclassified as recent by the Asanté™ HIV-1 Rapid Recency™ assay.
IV. To compare HIV incidence estimated using the Asanté™ HIV-1 Rapid Recency™ assay from a cross-sectional survey with that observed longitudinally in an observational cohort in Rakai.
|
Uganda |
2020-03-16 |
2023-03-16 |
Medical and Health Sciences |
|
Non-degree Award |
|
Robert Ssekubugu
ID: UNCST-2019-R001365
|
Prevalence of Oral Human Papillomavirus and HIV-infection in priority populations in South Central Uganda: a pilot study
REFNo: HS4937ES
Objective 1: Estimate the prevalence of HIV and OHPV and their impact on oral health conditions in Rakai and neighboring districts in South Central Uganda.
(a) Estimate the prevalence of HIV and OHPV infection;
(b) Estimate the prevalence of oral diseases (pre-cancerous lesions, oropharyngeal cancer, periodontal disease, dental decay);
(c) Estimate the extent to which OHPV, HIV, and OHPV/HIV co-infection is associated with an increase in the prevalence of oral diseases.
Objective 2: Identify the barriers to accessing oral health services among fisherfolk participating in Rakai and neighboring districts in South Central Uganda.
a) Explore the key perceived barriers to healthcare services, including STI and oral health services;
b) Explore the level of oral health understanding among community members;
c) Explore the pathways community members use to access oral health care services,
d) Identify environmental, personal, sexual, and other risk factors associated with the prevalence of common oral conditions, including tooth decay, periodontal problems, and OHPV.
|
Uganda |
2024-09-27 22:19:07 |
2027-09-27 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Hellen Nansumba
ID: UNCST-2019-R001368
|
Health care users’ knowledge, attitudes, and perceptions of broad consent for storage of biological materials and associated data in Uganda
REFNo: HS652ES
Main Objective
To evaluate the HCUs’ knowledge, attitudes, and perceptions of broad consent for storage of biological materials and associated data in a clinical setting in Uganda
Specific objectives
1. To assess HCUs’ understanding of essential elements of the informed consent form
2. To determine HCUs’ attitudes towards informed consent form
3. To determine the acceptability rate for storage of biological materials and associated data
4. To understand the of motivation of HCUs who accept for storage of biological materials and data
5. To assess HCUs’ perception of broad consent for biological materials and data
|
Uganda |
2020-07-01 |
2023-07-01 |
Medical and Health Sciences |
|
Non-degree Award |
|
Timothy Allen Peter
ID: UNCST-2019-R001369
|
Public Authority and International Devlopment
REFNo: SS92ES
The objective is to produce high-quality, evidence-based research that informs local, national and international policies to promote inclusive growth. Inclusive growth in many places in Africa and elsewhere has proved elusive. Formal governance can be remote, development policies persistently fail and humanitarian aid, at best, assists a minority. CPAID will use innovative approaches to research across disciplines and beyond narrow academic concerns. Our research will draw its understandings from ordinary people, and in particular vulnerable, marginalised and excluded groups and populations. CPAID will take public authority as its conceptual starting point, exploring the ways in which governance of people actually occurs. CPAID used the term public authority to refer to all forms of authority beyond the immediate family unit, from clans, religious institutions, aid agencies, civil social organisations, rebel militia and vigilante groups - to formal and semi-formal mechanisms of government. The public authority lens offers a new foundation for development discourse and hence for policy and interventions. It offers a set of tools for exploring African social and political realities. The lens offers an essential means of gathering evidence about these dynamics as well as the challenges and opportunities associated with them. Our research will be organised around studies of public authority at macro and micro levels to analyse: how public authorities regulate moral orders, deal with crimes (including regulation of sexually-based violence and the management of vigilantes), offer a degree of security and justice (including informal policing, and enforcing land rights); tax and redistribute fiscal resources socially and regionally; use and regulate new media technologies (including social media and mobile money); relate to disease control and health promotion (including tablet distribution for parasitic infections, the consequences of Ebola outbreaks and responses to non-biomedical health matters, such as witchcraft and spirit possession); and provide education and other public services (including allocation of land rights and land access). In all areas, we will be asking how public authorities function or do not function for ordinary people (including minorities and excluded sections of society). Our interest is in customary and neo-customary authorities as well as state ones. Distinguishing between state and customary authorities, as well as understanding how they interact, merge or generate hybrid new forms is an ambitious task that requires more grounded research. The research will also outline the processes by which effective and legitimate forms of public authority – those, which are delivering public goods and are inclusionary in orientation (i.e. do not aggressively exclude or oppress vulnerable groups and individuals) can be strengthened in practice. The research will draw upon the extensive research CPAID scholars have done on these issues, notably on the provision of security and justice in conflict affected and fragile settings .CPAID researchers have also made major contributions to the study of health-related institutions – including public health programmes, disease control and local or customary measures to promote wellbeing and the alleviation of suffering.
|
UK |
2017-07-20 |
2020-07-20 |
Social Science and Humanities |
|
Non-degree Award |
|
Timothy Allen Peter
ID: UNCST-2019-R001369
|
Public Authority and International Development Uganda Programme Phase 2
REFNo: SS1678ES
Inductive theory-building through comparative applications,New curriculum development for scholars and development professionals,Reciprocal capacity-building in the academy and knowledge production,Reflexive policy-making and governance impact,Generate impact, knowledge exchange and capacity building through a public authority lens,
|
UK |
2023-04-03 16:41:36 |
2026-04-03 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
henry bazira
ID:
|
DETERMINANTS OF MALE INVOLVEMENT IN ANTENATAL CARE IN MUKONO DISTRICT, UGANDA
REFNo: HS81ES
1. TO DESCRIBE THE LEVELS OF MALE PARTICIPATION IN ANTENATAL CARE SERVICES IN MUKONO DISTRICT.
2. TO ASSESS MEN’S ATTITUDES TOWARDS MALE INVOLVEMENT IN ANTENATAL CARE SERVICES IN MUKONO DISTRICT
3. TO ASSESS THE FACTORS ASSOCIATED WITH MALE INVOLVEMENT IN ANTENATAL CARE SERVICES IN MUKONO DISTRICT.
|
Uganda |
2017-07-13 |
2020-07-13 |
Medical and Health Sciences |
|
Degree Award |
|
Corrie Decker
ID:
|
Debating Childhood and Maturating in Colonial East Africa
REFNo: SS91ES
Between 1900 and 1960, missionaries, colonial officials, anthropologists, chiefs, elders, educated elites, and cultural nationalists in Uganda, Kenya, and Tanzania (at the time British colonial territories) came into conflict over whether or not to eradicate certain African customs governing a child’s maturation into adulthood. Demands to ban African customs are still heard in the international media today. Why were these debates so controversial at the time and why do they continue to invoke intense discord? I argue that these issues sparked such conflict because they dealt with differing opinions about how to manage a child’s maturation into adulthood. I investigate debates about rites of passage, puberty, adolescence, marriage, and definitions of the child culturally and legally in colonial East Africa. Many different viewpoints and approaches informed these debates, but they became polarized around two positions: the protection of the presumed innocent child in the name of universal rights, on the one hand, and, on the other hand, the preservation of cultural practices that fostered the child’s maturation toward normative adulthood. Scholars have pointed out that this struggle between universal human rights and culture was one that played out within the politics of colonialism and neocolonialism (Babatunde 1998; Hodgson 2011). These discourses portrayed the child as either a helpless creature in need of saving or a future productive and reproductive member of society. These debates shifted toward the end of the colonial era (1960s) as African teenagers’ greater independence became a source of anxiety as daunting as African nationalists’ demand for the end of colonialism (Burton and Charton-Bigot 2010; Ivaska 2011). This project spans the former British colonies of Uganda (1894-1962), Kenya (1895-1963), Zanzibar (1890-1963), and Tanganyika (1916-1961). I focus on the colonial era in order to show how East African customs became part of an international intellectual debate about child development and maturation.
|
USA |
2017-08-16 |
2020-08-16 |
Social Science and Humanities |
|
Non-degree Award |
|
Sofia Forss Ingrid Fredrika
ID:
|
Comparing the Effects of Early Experience and Cognitive Plasticity across the Great Ape Species
REFNo: NS27ES
The main aim of the project is to compare developmental- and experience effects both within and across ape species. First, I aim to investigate the influence of rearing histories (mother reared, wild born, sanctuary born, zoo housed, sanctuary housed, human hand reared etc) on cognitive skills within ape species. Second, by acknowledging individual differences due to rearing histories, this project will deliver meaningful comparisons, where individuals of similar experiences are compared across great ape species. In addition, it allows me to evaluate the strength of experience effects by examining if the change in problem-solving abilities linked to rearing experiences and human contact can even outweigh intrinsic species differences.
|
Finland |
2017-09-12 |
2020-09-12 |
Natural Sciences |
|
Non-degree Award |
|
Doreen Nabukalu
ID:
|
ASSESSMENT OF VILLAGE HEALTH TEAMS TO IMPROVE PUBLIC HEALTH SURVEILLANCE IN RURAL SOUTHWESTERN UGANDA.
REFNo: HS80ES
• To assess the performance of VHTs in the conduct of verbal autopsy and collection of vital statistics in a rural setting.
• To ascertain the leading causes of Adult Mortality in Bugoye sub county through facilitating of VHTs to conduct verbal autopsies in at least 75% of households in their villages by the end of nine months
• To ascertain the magnitude of various causes of Adult Mortality in Bugoye sub county through facilitating of VHTs to conduct verbal autopsies in at least 75% of households in their villages by the end of nine months.
• To examine the validity of adult mortality statistics gathered by VHTs by comparing health facility data and verbal autopsy data.
|
Uganda |
2017-08-07 |
2020-08-07 |
Medical and Health Sciences |
|
Non-degree Award |
|
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