Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Shevin  Jacob Thomas
ID:
STUDY OF WASH AND ANTIMICROBIAL RESISTANCE IN UGANDA (SWAR-U)
REFNo: HS489ES

Primary objective: To describe the transmission dynamics and ecological niches of ESBL-E and ESBL-K within selected households from Kampala and Hoima

Secondary objectives:
To evaluate the drivers of Water, Sanitation, and Hygiene (WASH) practices and their relation to the faecal-oral transmission of extended spectrum beta-lactamase producing Eschericia coli and Klebsiella pneumoniae

To create a dynamic agent-based model to evaluate the drivers of antimicrobial resistance transmission in Uganda, through the incorporation of microbiological resistance data (ESBL-E and ESBL-K) and WASH observational data obtained from all households included in the SWAR-U study

USA 2019-12-13 2022-12-13 Medical and Health Sciences Non-degree Award
Aala Abdelgadir
ID:
Mosque Mapping Survey
REFNo: SS385ES

Religious institutions play an important role in the daily lives of Ugandans, as in other African countries. Yet, we understand little about the influence of religious institutions on social and political outcomes. This project focuses on the sway of Muslim religious institutions in shaping the opinions and behaviors of congregants. Specifically, we will study how mosques communicate with congregants, what types of messages they deliver, and how messages shape the attitudes and behaviors of congregants.

The research objectives of this project are to:
• Examine variation in sermons, including topics, religious citations, and tone.
• Assess how mosque and imam characteristics influence the nature of sermons.
• Explore how sermons shape congregant religious, social, and political attitudes and behaviors.

USA 2020-03-12 2023-03-12 Social Science and Humanities Degree Award
Robert Wyrod
ID:
Opportunity in a New Era of Development
REFNo: SS388ES

Conduct research on the growing relationship between China and Uganda in the area of development. Understand the new opportunities for improving economic growth in Uganda through a growing relationship with China as a valuable new development partner.
USA 2023-01-20 14:20:54 2026-01-20 Social Science and Humanities Non-degree Award
Amy Young
ID:
Causes of under-five child mortality in the slum communities of Kampala, Uganda: A Verbal and Social Autopsy Study
REFNo: HS507ES

The study seeks to identify the biomedical causes of death as well as the sociodemographic, behavioral and environmental factors associated with child mortality in the slum communities of Kampala. This includes recognition of illness, decisions around care-seeking, and care-seeking behaviors.
USA 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
THE AFRICAN RESEARCH COLLABORATION ON SEPSIS IN UGANDA (ARCS-UGANDA) COHORT STUDY: AN OBSERVATIONAL STUDY TO IMPROVE UNDERSTANDING OF SEPSIS EPIDEMIOLOGY, DEFINITIONS, HOST IMMUNE RESPONSE AND COSTS OF HOSPITAL CARE IN UGANDAN ADULTS
REFNo: HS511ES

General Objective:
To describe adult sepsis prevalence and incidence, validate sepsis definitions, characterize AMR, describe short- and long- term morbidity and mortality, identify host response to sepsis and quantify hospital costs using a cohort of adult patients with suspected sepsis admitted to hospitals in Uganda

Specific objectives:
1. Determine the epidemiologic characteristics, AMR characteristics, clinical outcomes (including morbidity, mortality and frequency of readmission after discharge from the hospital) and attributable costs from suspected sepsis in Ugandan hospitals
2. Evaluate performance characteristics of extant sepsis definitions/criteria when applied to a cohort of adult patients who fulfil study eligibility criteria for sepsis in Uganda
3. Characterize pathways of sepsis pathogenesis through exemplar pro-inflammatory (through neutrophil respiratory burst activity) and immunosuppressive (through HLA-DR) markers and agnostic transcriptomic analysis in a Ugandan sepsis cohort with a high prevalence of HIV infection.

USA 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Sara Weschler Weschler
ID:
Deep Roots and Bitter Greens: Legacies of Colonial-Era Forced Displacement in Western Acholiland
REFNo: SS419ES

For my Master’s thesis research I studied the way British colonial officials used Sleeping Sickness control measures to justify the forced relocation of the entire population of western Acholiland between 1911 and 1920. For my PhD dissertation research, I will use qualitative interview methods to explore how the history of this early colonial-era forced displacement is remembered and understood in Acholiland today. I intend to examine what sorts of socio-cultural changes colonial-era displacement precipitated in Acholiland. At the same time, though, I hope to trace examples of cultural resilience and examine how Acholi culture and society recovered from these upheavals over the course of the intervening century.
USA 2020-02-19 2023-02-19 Social Science and Humanities Degree Award
Catherine Carlson
ID: UNCST-2023-R007222
Promoting Resilience for Survivors of Trafficking: Evaluating a Yoga-Based Approach in Kampala, Uganda
REFNo: SS420ES

Healing and Resilience through Yoga (Hart Yoga) is a trauma-informed yoga program to support survivors of human trafficking in Uganda with psycho-social recovery. The
proposed study will evaluate Hart Yoga’s feasibility, acceptability and impact with women and adolescent girls residing in Willow International’s (https://www.willowinternational.org/) shelters for survivors of human trafficking in Kampala, Uganda. This study will advance the limited field of health and mental health research with survivors of human trafficking and provide pilot data for publication and the development of a subsequent effectiveness trial. The methodology will address two primary objectives:

• Objective 1: To determine Hart Yoga’s feasibility and acceptability among participants and successful delivery within a residential shelter setting.
• Objective 2: To assess physical, psychological and social outcomes among program participants using qualitative and quantitative methods.

USA 2020-03-18 2023-03-18 Social Science and Humanities Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
Outcomes Following Surgical Release of Gluteal Fibrosis in Children of Eastern Uganda
REFNo: HS561ES

This study is a longitudinal case series to evaluate if surgical release of gluteal fibrosis in Ugandan children has a sustained benefit. We will examine the two-year outcomes after surgical release of gluteal fibrosis in children undergoing surgical intervention for gluteal fibrosis.

USA 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
Kristen Reid
ID:
COVID-19 in Uganda: Epidemiology and Treatment Outcomes of the First 75 Cases
REFNo: HS677ES

3. To describe both immediate and intermediate outcomes of the first 75 Covid-19 patients in Uganda up to 6 months post discharge.,2. To describe the course of illness and treatment of the first 75 cases of COVID-19.,1. To describe the characteristics and clinical manifestations of the first 75 consecutive cases of COVID-19 infection in Uganda.,
USA 2020-07-15 2023-07-15 Medical and Health Sciences Non-degree Award
Travis  Curtice Benjamin
ID:
Public Health, Trust, and Livelihoods: The Case of COVID19 in Uganda
REFNo: SS465ES

The key objectives of this study are to explore 1) how support for, and trust in state institutions shape individuals’ responses to public health crisis caused by the Coronavirus; and 2) more generally, the effect of COVID19 on income and livelihoods in a low-income country setting.

Overall Objectives
The coronavirus continues to spread across the globe. While there have been several early assessments of individuals' concerns and behavior in response to the shifting landscape of the pandemic, most work thus far has concentrated in OECD countries. We therefore know far too little about the impact of the Coronavirus on everyday life in low-income countries, where the virus has made a late entry. Focusing on the case of (rural) Uganda, our proposed study aims to close this gap. Results from this study will provide important insights into the relationship between trust in the government and public health and the impact of the public health crisis on migration, money transfers, and economic and food insecurity.

We propose to conduct a short phone survey that builds on a recently completed randomized control trial (RCT). The follow-up survey will allow us to test whether trust in political institutions are important not only in shaping individuals’ attitudes (e.g., their assessment of governments mitigating actions), but also their preventative health behaviors in response to the novel Coronavirus in Uganda. We are also interested in documenting how the Coronavirus is affecting the livelihood and wellbeing of the rural poor in a low-income country setting, where Covid-19 research has been sparse.

USA 2020-07-17 2023-07-17 Social Science and Humanities Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
KarenBeth Bohan Heikkinen
ID:
Assessment of Online Modules to Increase Knowledge of Geriatric Care in Health Care Professionals RefNo: MAKSHSREC-2020-6
REFNo: HS727ES

To determine the pharmacists’ satisfaction with pharmacy geriatric online training.,To determine the learning preference in terms of online compared to live educational sessions before and after using the online modules for professional development,To determine the retention of knowledge of geriatric care at three months after completion of all five online educational modules.,To assess the improvement of pharmacy professionals’ knowledge of geriatric care after participating in online educational modules.,
USA 2020-09-29 2023-09-29 Medical and Health Sciences Non-degree Award
Sona Shah
ID:
Adoption of a wireless vital sign monitor for observation of COVID-19 patients
REFNo: HS733ES

1. To evaluate the feasibility of a wireless vital sign monitor for use on critical patients in COVID-19 treatment facilities
2. To assess the accuracy of a wireless vital sign monitor (neoGuard) on adult patients
USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Dorit Stein Talia
ID: UNCST-2022-R010349
Policy Lessons from the COVID-19 Response in Uganda: Exploring Subnational Variation in the Maintenance of Essential Health Services for Women and Children
REFNo: SS1386ES

1. Measure and assess variation in district-level implementation of national guidelines to maintain delivery of essential health services in the context of COVID-19 across key health systems functions
2. Assess whether implementation of guidelines explains variation in performance for maintaining essential RMNCH services during the first year of the pandemic
3. Develop policy recommendations to improve governance of essential service delivery during emergencies

USA 2022-08-12 13:58:11 2025-08-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nathan Fiala
ID: UNCST-2022-R009060
The Long-term Impacts of a cash-based Employment Program in Northern Uganda
REFNo: SS501ES

1.To evaluate the long-term effectiveness of a cash-based youth employment program using a randomized controlled trial.
2. To understand the effect of COVID-19 and restrictions on youth employment
USA 2020-09-16 2023-09-16 Social Science and Humanities Non-degree Award
Matthew Bird Aileen
ID:
Consumer Protection Survey
REFNo: SS523ES

In this study, we aim to generate insights on consumer protection topics related to mobile telecommunications and digital finance in Uganda. Areas to be explored through this nation-wide phone survey include consumer usage and preferences regarding service providers, levels of trust, pricing awareness, challenges, fraud, dispute resolution, and the impact of COVID-19 on these topics. This project is being conducted in partnership with the Uganda Communications Commissions (UCC).
USA 2020-08-10 2023-08-10 Social Science and Humanities Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Assessing Health Professionals’ Knowledge, Perspectives and Practices Regarding HPV and Cervical Cancer Prevention and Control among Women Living with Human Immunodeficiency Virus Infection in Uganda
REFNo: HS782ES

General Objective The proposed study seeks to examine the role that health professionals play in influencing WHIVs’ perceptions of HPV and cervical cancer and their associated health behaviors in Uganda.

Specific Objective
Interview public health and health care professionals (including clinicians, nurses, counselors, other/public health professionals, and community health workers/village health teams) to examine the following:
1. Knowledge regarding how HPV or cervical cancer impacts WHIV, which populations are impacted most, and frequency of HPV vaccination, screening and treatment. 2. Perspectives regarding barriers/facilitators of cervical cancer and HPV prevention and treatment among WHIV. 3. Practices regarding HIV professionals’ work in cervical cancer and HPV.
USA 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Warren Phipps
ID:
Attitudes and Practices of Antimicrobial Resistance and Stewardship at the Uganda Cancer Institute
REFNo: HS871ES

We will investigate the knowledge, attitudes, and practices about antimicrobial use and antimicrobial resistance among the doctors (including medical officers, fellows, oncologists, and surgeons), nurses, and pharmacists at the Uganda Cancer Institute (UCI).

The aims of the study are;
Aim 1: To examine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial resistance.
Aim 2: To determine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial stewardship.
Aim 3: To understand perceived barriers to the diagnosis and management of infections in patients at UCI

USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Geospatial Analysis of Kampala Cancer Registry Data
REFNo: HS873ES

Objective 1: Identify spatial and spatiotemporal patterns of cancer in Uganda. a) Use geospatial mapping techniques to estimate cancer burdens across geographic space and through time. b) Create visual representations of cancer patterns (maps, graphs). Objective 2: Examine relationships between social and environmental factors and cancer outcomes in Uganda. a) Use statistical analysis techniques to determine associations between environmental factors and cancer outcomes. Objective 3: Pilot the collection of new KCR variables a) For each new case, we will attempt to acquire marital status, education level, occupation, religion, national Identification number (NIN) (new in Uganda), and precise geographic location information. Objective 4: Determine the true spatial extent of KCR data collection potential. a) Identify the number of cases that are discovered and excluded under current practice, as well as the individual’s parish of residence.
USA 2020-09-28 2023-09-28 Medical and Health Sciences Non-degree Award
Daniella CHUSYD Elyse
ID:
Anthropogenic related stress on reproduction in African forest elephants (Loxodonta africana cyclostis)
REFNo: NS137ES

(i) To determine how human activity influences elephant stress and reproduction.

(ii) To assess Elephants’ allostatic load (measure of the wear and tear on the body) in relation to proximity to humans.

(iii) To determine Elephants’ reproductive cycling status (is the elephant cycling or not) in relation to the elephant’s allostatic load.

USA 2021-07-30 2024-07-30 Natural Sciences Non-degree Award
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