Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Cynthia Moffitt
ID: UNCST-2022-R011033
 Improving Adherence to Malaria Treatment Guidelines in Children at a Ugandan Regional Hospital
REFNo: HS2633ES

1. To determine the current level of adherence to severe malaria treatment protocols at MRRH. 2. To determine the factors responsible for poor adherence to severe malaria treatment protocols. 3. To assess the treatment outcomes at the current severe malaria treatment protocol adherence. 4. To design an adherence improvement intervention
 USA 2023-01-18 17:51:42 2026-01-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rena Deitz
ID:
Do good intentions translate? The rise, transfer, and localization of Social Emotional Learning (SEL)
REFNo: SS1325ES

To develop a locally relevant measure / instrument of SEL that can be used by education practitioners in Uganda,To provide youth (refugee and host community) the skills and experience in co-designing a research instrument,To assess the differences between locally and globally defined SEL,To understand the transfer of "social emotional learning" (SEL) through foreign aid and the differences between local and global values around SEL,
 USA 2022-08-11 15:40:14 2025-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Carlson
ID: UNCST-2023-R007222
 Adolescent Mental Health and COVID-19 in Uganda
REFNo: SS1238ES

1. To understand the lived experiences of children in Uganda during the Covid-19 school closures and how those experiences affected their mental health.
2. To understand how children, teachers, and other school staff view the role of schools in supporting children’s mental health “after” the pandemic.
3. To assess any initial supports schools have provided to support students' mental health as they reopen in 2022.

 USA 2022-06-29 14:11:27 2025-06-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alexandra Sacco
ID:
Population Health in Endangered Red Colobus Monkeys in Kibale National Park
REFNo: NS336ES

1) Disentangle the impact of various factors on gut microbial community structure of female red colobus monkeys (Piliocolobus tephrosceles) that live in disturbed and old-growth areas across Kibale National Park, Uganda, and (2) characterize the interactions between gut microbes and female sex hormones over the reproductive cycle.
USA 2022-05-06 13:44:47 2025-05-06 Natural Sciences Non-Clinical Trial Degree Award
Peter Jackson Durham
ID: UNCST-2022-R010933
 Investigation of Serologic and Pulmonary Mediators of post-Tuberculosis Lung Fibrosis in a Ugandan cohort
REFNo: HS2172ES

Primary objective:
-To analyze the levels of cytokines and SPM’s in the blood and exhaled breath of patients with pulmonary TB at diagnosis, 6 months and one year to determine if there are differences in cytokine and SPM expression among patients who develop PTLI and those who do not.
Secondary objectives
-To identify socio-demographic and clinical risk factors associated with PTLI development and investigate associations of these characteristics with specific PTLI phenotypes.
-To document the quality of life among patients who develop PTLI. ? To develop a biobank of EBC and serum samples from subjects with PTLI and those with resolution of their lung impairment at diagnosis, conclusion of treatment and at one year from diagnosis.
 USA 2022-05-04 11:28:09 2025-05-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lisa Hartwig
ID:
The effectiveness of a behavioral science and design intervention for family savings on increased use of maternal health services and male involvement: a randomized controlled trial
REFNo: HS2194ES

To assess the effectiveness of a behavioral intervention designed to encourage financial savings for healthcare costs and birth preparedness among pregnant women and their partners in Uganda. To examine whether increased earmarked financial savings for healthcare costs leads to increased utilization of maternal health services and male involvement in maternal healthcare.
 USA 2022-05-23 9:28:49 2025-05-23 Medical and Health Sciences Clinical Trial Degree Award
Sebastian Linnemayr
ID: UNCST-2021-R012696
 Goals for Adherence with Low-cost Incentives (GOALS)
REFNo: HS2207ES

The objective in year 1 is to identify the incentive design most effective for improving adherence.
The objective in year 2 is to maintain adherence improvements at the clinically optimal level of 90 percent and achieve viral suppression.
The objective in year 3 is to measure adherence for 12 months after the intervention ends to assess the impact of the different treatment arms on behavior change once incentives are withdrawn (persistence).

USA 2022-04-14 2025-04-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Parkinson
ID: UNCST-2022-R010888
 Exploring Human Origins in the Albertine Rift Valley, Uganda
REFNo: SS1257ES

This project will conduct paleoanthropological research in central Africa, at fossil sites located near the shores of Lake Albert in the western branch of the Rift in western Uganda (Albertine Rift). Our goal is to investigate the diversity of adaptive challenges faced by early human ancestors, in order to better understand the forces driving human evolution. We will document the distribution and age of sites, collect and describe new fossil and archaeological evidence, and re-examine previous collections in the Uganda Museum. Drawing on the team’s expertise in innovative approaches in archaeology, paleoecology, and geochronology, we aim to renew human origins research in this underexplored region.
 USA 2022-06-16 14:43:10 2025-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Travis Baseler Andreas
ID:
The Effects of Voluntary Relocation and Forced Displacement by Natural Disasters: Evidence from Ugandan Landslides
REFNo: SS1263ES

We intend to study the economic effects of displacement following environmental disasters, with a focus on the displaced population. Our goal is to identify mechanisms behind economic outcomes for the displaced, to inform future adaptation policy and humanitarian responses. The setting of this study is landslide episodes in Eastern Uganda in 2010-2019, which have displaced nearly 10,000 people.
 USA 2022-05-12 8:00:58 2025-05-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benigno Alonzo Jr
ID:
Dry Rifting In the Albertine-Rhino Graben, Uganda (DRIAR)
REFNo: NS347ES

A geophysical, geochemical, geological, and geodynamic investigation of the Albertine-Rhino Graben in western and northwestern Uganda to improve our understanding of continental rifting in areas where volcanic activity is minimal.
USA 2022-07-06 10:20:32 2025-07-06 Natural Sciences Non-Clinical Trial Non-degree Award
Jane Fieldhouse
ID:
One Health Timeliness Metrics: Stakeholder Experiences in Multisectoral Outbreak Reporting
REFNo: HS2255ES

The general objective of this proposal is to evaluate timeliness, or speed of detection and response, during multisectoral outbreak events in Uganda. Quantitative and qualitative analyses of One Health timeliness metrics will be used to make recommendations for a One Health outbreak reporting tool designed to monitor progress toward finding and responding to outbreaks faster.
 USA 2022-06-06 11:39:24 2025-06-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Samuel Davidoff-Gore Asher
ID:
Socioeconomic Inclusion of Migrant and Forcibly Displaced Women in Cities in West Africa and the Horn of Africa: What Opportunities and Challenges Exist in a Post-COVID-19 World?
REFNo: SS1300ES

This study seeks to understand what the challenges are across these urban contexts, and how development and humanitarian actors need to adapt their programming approaches along with modus operandi. In particular, it explores the following three levels:
• The gender effects of the COVID-19 pandemic and specific challenges faced by female migrants and forcibly displaced women in terms of access to services and livelihoods depending on the urban context, in West Africa and in the Horn of Africa.
• How donors, humanitarian and development actors, as well as national and local governments, the private sector, and civil society have provided economic and social assistance during the health crisis, to what extent these interventions and policies have addressed the socioeconomic challenges faced by migrant and forcibly displaced women and contributed to gender equality.
• Moving forward, how development actors can work towards better including forcibly displaced and migrant women in recovery efforts and overcome the barriers to their inclusion, and how these initiatives should differ based on the urban context (e.g., capital city; border town; small city).

USA 2022-05-26 9:04:08 2025-05-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Holly Koogler
ID:
Social Relationships and Child Labor Migration from Karamoja, Uganda: An Exploratory Study
REFNo: SS1302ES

•Investigate the social risk factors related to child labor migration •Explore the nuances of the social lives of child labor migrants, including both strengths and negative aspects of social relationships •Propose policies and potential interventions that reflect the true structure and dynamics of social networks for preventing child labor migration, mitigating the most dangerous forms, and withdrawing migrant children from labor
 USA 2022-05-30 17:20:41 2025-05-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jennifer Verdolin
ID:
Testing the Feasibility of Community Driven Course Development: A New Paradigm in Equity, Diversity, and Inclusion
REFNo: NS364ES

Together with local community experts create two university level online courses in the areas of wildlife conservation and ecotourism. The courses, when offered to students outside of Uganda will incorporate profit sharing so that part of the tuition fees go back to the communities that helped develop the courses.

1. Collaborate with Conservation Through Public Health (CTPH) to connect with local community experts to
develop two online university courses in wildlife conservation and ecotourism.

2) Provide guest lectures and workshops to faculty at Kabale University on science communication and online course development

3. Conduct a special podcast series: Voices of Uganda where I invite community members and local experts to share their experience.

4. Develop a strategic plan development to recruit university partners
 USA 2022-09-29 13:34:29 2025-09-29 Natural Sciences Non-Clinical Trial Non-degree Award
Lina Rademacher Ann
ID:
Female Reproductive Strategies in Vervet Monkeys
REFNo: NS369ES

To gain insight into female choice in vervet monkeys and how it changes throughout the ovulatory cycle.
To gain a better understanding of the ovulatory cycle in vervets using hormonal analysis from feces which has not previously been done for this species.
 USA 2022-08-03 11:20:59 2025-08-03 Natural Sciences Non-Clinical Trial Degree Award
Kearsley Stewart
ID: UNCST-2021-R011830
 Reducing Sickle Cell Burden in Kalangala, Uganda: A Student Research and Training Program
REFNo: HS2312ES

Aim 4: To develop educational activities for adolescent sickle cell patients (non-research) We aim to develop non-research, educational activities specifically designed for adolescent sickle cell patients who attend the monthly sickle cell clinic at Kalangala Health Center. Activities will include a “kids camp” that will train older children to share their experiences managing their sickle cell disease with younger clinic patients. Also, we will establish a “MDD Troupe”, or “Music Dance and Drama Troupe” to spread awareness about sickle cell in community settings such as schools and youth clubs. These activities are not part of the testing initiative, nor are they generalizable research. However, these activities will be conducted by Duke undergraduate students in collaboration with Ugandan students from Kalangala - this is part of the “student research training program the “twins” or matches Ugandan and US-Based students on collaborative teams.,Aim 3: Conduct a retrospective chart review of all SCD patients at KHCIV since 2015 Conduct a retrospective chart review of all sickle cell patients appearing in various KHCIV paper-based databases (Ministry of Health Outpatient Register 002, registries, laboratory forms, death records, etc) since the opening of the KHCIV sickle cell clinic in 2015. Build a standardized form to record data such as medical history, demographics, clinical data, pain episodes, routine and acute clinic visits, etc.,Aim 2: To increase community knowledge and understanding about SCD and the importance of diagnostic testing for Kalangala. We aim to increase community knowledge about SCD through a community educational component that will complement the testing initiative. Study participants will go through an education module prior to testing that will describe SCD, symptom management and treatment options, the importance of testing, and SCD-related stigma. Study participants will also be briefed on their options for counseling post SCD testing, in the event of a positive diagnosis. ,Aim 1: To improve access to sickle cell RDTs and establish a standard RDT for Kalangala, Uganda. We aim to improve access to screening and confirmatory sickle cell RDTs and establish a standard RDT that best fits the health infrastructure in Uganda, specifically Kalangala Health Center IV, which is the government referral health center for Kalangala District. Another goal is to increase the capacity of local health centers to diagnose patients efficiently, informing more of the population of their status and treatment options, and lowering SCD disease burden in the area over time.,The main objective of this study is to reduce the burden of sickle cell disease in Kalangala, Uganda through rapid testing, education, and retrospective patient chart review. This pilot study aims to identify methods and tools to mitigate the burden of SCD, increase community awareness of SCD diagnosis status, improve knowledge and understanding of SCD within the Kalangala community, and better understand retrospective trends in health indicators of sickle cell patients in Kalangala, Uganda. ,
 USA 2022-06-28 17:17:19 2025-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shevin  Jacob Thomas
ID: UNCST-2022-R010715
 Evaluation of Supportive Care Guidelines for Epidemics: Implementation Case Study: Filovirus Diseases (FVDs) and Covid-19 guidelines in Uganda.
REFNo: SS1320ES

Main objective:
to understand implementation practices, challenges and experiences of providing clinical management guidelines (CMGs)/ providing supportive care recommendations for patients with VHFs and/or COVID-19 in Uganda.

specific:

1) implementation of CMGs for a selection of high-risk epidemic prone pathogens
2) factors influencing implementation in different settings and contexts
3) perceived impact of available CMGs and supportive care recommendations on research and development for medical countermeasures and on outcomes
4) experiences of key informants who led CMG development and contributed to the evolution of CMGs in epidemics
5) community-level perceptions in any changing quality of care during the evolution of CMGs.
6) any changing essence and meaning to patient journeys during the expansion and implementation of CMGs

USA 2022-08-08 19:07:46 2025-08-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Tapscott
ID:
Uganda's Resistance Councils
REFNo: SS1322ES

Main objective - Study the process of establishment of the Resistance Councils and their institutional features, both during the war and especially in the immediate post-war years. Specific objectives - Explore the role of the Resistance Councils in areas beyond Luwero. - Document the institutional features of the first Resistance Councils. - Study the process of establishment of the Resistance Councils, especially in the immediate post-war years.
 USA 2022-07-20 17:49:18 2025-07-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda (Experimental Phase)
REFNo: SS1324ES

The study objectives are as follows:
1. To determine whether business relocation within Kampala can increase profits for mobile microentrepreneurs (primary objective)
2. To identify which constraints might restrict microentrepreneurs’ business locations within the city by separately relieving information and liquidity constraints (secondary objective)
 USA 2022-06-28 16:47:30 2025-06-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Shevin  Jacob Thomas
ID:
Oxygen requirements and approaches to respiratory support in patients with COVID-19 in low- and middle-income countries: a WHO study
REFNo: HS2399ES

1. To characterize the type and duration of different modalities of respiratory support delivered to patients with suspected or confirmed severe and critical COVID-19 in LMICs. a. To quantify the amount (m3 and L/min.) of oxygen delivered to patients with suspected or confirmed severe and critical COVID-19 in LMICs b. To describe practice patterns in escalation and de-escalation of oxygen therapy and respiratory support for patients with suspected or confirmed severe and critical COVID-19 in LMICs 2. To describe baseline demographics and hospital outcomes of hospitalized patients with COVID-19 3. To describe facility-level characteristics for oxygen delivery and respiratory support
USA 2022-08-23 17:18:56 2025-08-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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