Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Francis Ssenkuba
ID: UNCST-2023-R005471
POINT-OF-CARE MONITORING OF SCHISTOSOMIASIS AND FASCIOLOSIS IN LAKE ALBERT, SOUTHWESTERN UGANDA: OPTIMISING THE ENVIRONMENTAL DNA DUPLEX QPCR
REFNo: NS1175ES

i. To develop and optimise a field deployable point of care duplex qPCR for simultaneous detection of Schistosoma mansoni and Fasciola spp. from water environmental samples. ii. To determine the influence of seasonal dynamics of biotic and abiotic factors on Schistosoma and Fasciola eDNA detection in the L. Albert region. iii. To map the actual transmission of human and bovine schistosomiasis and fasciolosis in real time to guide prevention and control interventions. iv. To evaluate the efficacy of the selected snail control measures in schistosomiasis and fasciolosis control using eLAMP and the optimised duplex qPCR assay.
Uganda 2026-03-03 12:22:53 2029-03-03 Natural Sciences Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of The Safety, Efficacy and Stability of Sangaphos® Emulsifiable Concentrate [E.C]: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricide Field Trial
REFNo: NS1171ES

General objectives: To determine the efficacy, safety, and stability of SangaPhos [Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve] when applied onto cattle by hand spraying and plunge dipping for tick control. Specific objectives The specific objectives of this acaricide field trial will to determine; i.Efficacy of Sangaphos® when applied onto cattle by hand spraying and plunge dipping for tick control. ii.Safety of Sangaphos® when applied onto cattle by hand spraying and plunge dipping for tick control. iii.Stability of Sangaphos® when applied onto cattle by plunge dipping for tick control.
Uganda 2026-03-03 12:23:56 2029-03-03 Natural Sciences Clinical Trial Non-degree Award
Kigai ErickEvansBigala
ID: UNCST-2026-R023324
Characterisation of Selected Arboviruses in Ticks, Rodents, and Livestock in the Albertine Ecosystem of Uganda
REFNo: NS1156ES

1. To determine the species diversity and distribution of rodents in selected areas of the Albertine ecosystem.
2. To determine arboviruses, present in the ticks, small mammals and livestock through metagenomic sequencing.
3. To identify the risk factors and seroprevalence associated with Wesselsbron virus (WSSLV) and the Crimean-Congo Haemorrhagic Fever virus (CCHFV) infection in rodents and livestock in selected areas of the Albertine ecosystem.
4. To characterise the Wesselsbron virus (WSSLV) and Crimean-Congo Haemorrhagic Fever virus (CCHFV) in ticks, small mammals, and livestock in selected areas of the Albertine ecosystem.
Uganda 2026-03-03 12:24:52 2029-03-03 Natural Sciences Non-Clinical Trial Degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
Causality of Post-TB Lung Disease: Population-Level evidence from Rural Uganda.
REFNo: HS7131ES

Aim 1. Prospectively characterize trajectories of lung function before and after tuberculosis (TB) disease, stratified by HIV status and compared against matched controls who do not develop TB.
Aim 2. Identify baseline characteristics and biomarkers associated with TB-attributable lung function decline.
Aim 3. Project the long-term burden of PTLD that could be averted through TB prevention and other interventions (e.g., smoking cessation, nutritional support).

Uganda 2026-03-03 12:27:40 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Asiimwe
ID: UNCST-2019-R000059
The PULM Uganda Study (Predicting Lung Health Mechanisms in Uganda)
REFNo: HS7089ES

This study aims to identify individuals at highest risk for chronic obstructive pulmonary disease early in the disease course and intervention targets for preventing disease progression
Uganda 2026-03-03 12:29:28 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lordrick Alinaitwe
ID:
Knowledge Attitude and Practices of Rural Livestock Farmers in Western Uganda Toward Zoonotic Diseases Prevention
REFNo: SS4877ES

To provide recommendations for strengthening district-level One Health programming and farmer-focused interventions based on the findings.,To document perceived barriers and enablers that affect farmers’ adoption of zoonotic disease preventive practices.,To identify sociodemographic and farm-level factors associated with KAP scores among livestock farmers.,To measure the level of knowledge, attitudes, and practices related to zoonotic disease prevention among rural livestock farmers in the study area.,To assess the knowledge, attitudes, and practices of rural livestock farmers in Western Uganda, regarding zoonotic disease prevention, and to identify factors influencing these aspects.,
Uganda 2026-03-03 12:30:46 2029-03-03 Social Science and Humanities Degree Award
Silver Onyango
ID: UNCST-2022-R009337
The AWARE Study (Air Pollution and Well-Being: Assessing Risks and Enhancing Education in Uganda
REFNo: HS7082ES

This study aims to use focus group discussions to develop a conceptual framework to explain facilitators and barriers to reducing personal air pollution exposure among adults
Uganda 2026-03-03 12:32:49 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GUMOSHABE TARASIS
ID: UNCST-2025-R020755
DETERMINANTS OF HEALTHCARE SERVICE UTILISATION AMONG CHILDREN UNDER FIVE IN RURAL SETTINGS OF BUDAKA DISTRICT, UGANDA
REFNo: HS7080ES

1.To assess the proportion of children under five who utilised formal healthcare services among those who experienced childhood illness in the past six months in rural Budaka. 2.To determine the child-related factors influencing healthcare service utilisation among children under five in rural communities of Budaka District 3.To assess the enabling factors influencing healthcare service utilisation among children under five in rural communities of Budaka District 4.To determine the need factors influencing healthcare service utilisation among children under five in rural communities of Budaka District
Uganda 2026-03-03 12:34:24 2029-03-03 Medical and Health Sciences Non-Clinical Trial Degree Award
James Tumusiime
ID: UNCST-2025-R022872
Rethinking viability in a converged environment: A qualitative analysis of business model adaptation in Uganda's newspaper industry
REFNo: SS4971ES

i. To qualitatively analyse how the integration of traditional and digital media platforms driven by media convergence has reshaped the business models of New Vision and Daily Monitor.
ii. To explore the perceptions of media owners, newsroom leaders and media experts towards the viability of the business models of New Vision and Daily Monitor in the digital age.
iii. To examine how the differences in public and private ownership structures influence how New Vision and Daily Monitor respectively adapt their business models in a converged media environment.
iv. To evaluate the role of non-traditional and non-media revenue streams in supporting the viability of New Vision and Daily Monitor in a converged media environment.

Uganda 2026-03-03 12:37:12 2029-03-03 Social Science and Humanities Non-Clinical Trial Degree Award
Solomon Mwije
ID: UNCST-2025-R022614
Exploring the potential of Photovoice toward strengthening social accountability through Citizen Science and Community-Based Monitoring initiatives. The RIDE-AFRICA’s Participatory Action Research Project, Kyenjojo District, Uganda
REFNo: SS4783ES

1. To understand how different photovoice mechanisms influence the citizen-state interface in extreme CBM initiatives.
2. To assess how different photovoice mechanisms influence citizen mobilization in extreme CBM initiatives.
3. To explore whether photovoice increases citizens’ and duty-bearers’ awareness in extreme CBM initiatives
4. To examine the extent to which photovoice influences citizens’ and duty-bearers’ actions in extreme CBM initiatives
Uganda 2026-03-03 12:39:22 2029-03-03 Social Science and Humanities Non-Clinical Trial Degree Award
Solomon Lukoda
ID: UNCST-2025-R023096
RISE Uganda Context Analysis & Learning Support
REFNo: SS4837ES

1. Context Analysis: This scoping study will be conducted in Uganda to provide insights to the Foundation and its partners in the planning phase of the pilots. 2. Learning Support: This is aimed at filling existing knowledge gaps, facilitating learning and setting up adaptive management processes for the Foundation and its partners as the programme reaches the implementation stages, that will inform adaptation in existing countries and roll out to new countries.
Uganda 2026-03-03 12:43:00 2029-03-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
simpson kamugisha
ID: UNCST-2024-R003681
A Pilot Qualitative Study of the Lived Experiences of Boda Boda Drivers in Uganda
REFNo: SS3731ES

1. What are the experiences of boda boda drivers with medical care after traffic accidents? 2. 2. How do boda boda drivers care for their mental well-being after serious traffic accidents? 3. 3. What protective factors support the health and wellness of boda boda drivers when faced with adversity?
Uganda 2026-03-03 12:45:20 2029-03-03 Social Science and Humanities Non-Clinical Trial Degree Award
Godfrey Kubiriza Kawooya
ID: UNCST-2024-R003138
An investigation of the development of Nutrient-Enriched Protein Food Products from Stunted Fish, Insects and Spirulina for Improved Nutrition among School-going Adolescents
REFNo: A732ES

Overall Objective The aim of the study is to evaluate the potential of the non-conventional protein sources as ingredients for production of affordable protein-rich products to improve nutrition of school-going adolescents. Specific objectives 1. To characterize the nutritional profiles of developed composite protein-enriched products (bars, soups, baghia) developed from crickets, small-sized (stunted) Nile tilapia and spirulina. 2. To evaluate the safety (microbial, and chemical) of the bars, soups and baghia 3. To assess the acceptability of the bars, soups and baghia 4. To determine the shelf life of the bars, soups, and baghia
Uganda 2026-03-03 12:46:51 2029-03-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
Bambeiha Asiimwe Stephen
ID: UNCST-2024-R003555
Mapping HIV and AIDS research in Uganda based on the national HIV and AIDS research agenda
REFNo: HS6892ES

1. To map completed, ongoing and planned HIV and AIDS research in Uganda in the period of 2015-2025 by the thematic areas of the national HIV and AIDS research agenda 2. To explore challenges and opportunities for the generation and application of HIV and AIDS knowledge in Uganda 3. To explore opportunities for linkages and collaborations across local governments, Universities, and communities that can support better generation and application of HIV and AIDS knowledge
Uganda 2026-03-03 12:48:22 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacinta Namakoye
ID: UNCST-2025-R016920
MACHINE LEARNING MODEL FOR PREDICTION OF CHOLERA IN RUBAGA DIVISION, KAMPALA DISTRICT
REFNo: HS6964ES

i. To analyze the key predictors influencing cholera outbreaks in Rubaga division ii. To develop machine learning models that generate early-warning predictions of cholera outbreaks to support public health decision-making in Rubaga division iii. To evaluate the predictive performance and accuracy of the developed models
Uganda 2026-03-03 12:52:00 2029-03-03 Medical and Health Sciences Degree Award
Richard Ssewakiryanga
ID: UNCST-2026-R023427
The Impact of Digital Tax Stamp (DTS) in Uganda
REFNo: SS4777ES

1. Access the legal, regulatory, and institutional framework governing DTS.
2. Evaluate the effects of DTS on revenue, compliance, and enforcement outcomes across covered products, and
3. Examine the effectiveness of DTS in addressing countering smuggling and illicit market practices.
Uganda 2026-03-03 12:53:55 2029-03-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Brian Otaalo
ID: UNCST-2025-R022795
Exploring Antibiotic Prescribing Behavior Among Healthcare Providers in HIV Clinics: A Qualitative Study in Uganda.
REFNo: HS7056ES

1. To explore the determinants of health workers’ antibiotic prescribing behavior in HIV health care settings in Kampala, Uganda. 2. To explore healthcare workers’ views and ideas for potential antimicrobial stewardship interventions in HIV health care settings in Kampala, Uganda.
Uganda 2026-03-03 12:56:39 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martin Ariapa
ID: UNCST-2021-R013296
The drivers of teacher wellbeing and retention in contexts of protracted violence and displacement
REFNo: SS4796ES

Study objectives To identify effective strategies for supporting teacher wellbeing and strengthening teacher retention in crisis-affected regions of Uganda. Specific objectives 1. To examine how teachers and informal community networks mitigate the effects of violent conflict, displacement, and related crises on teacher wellbeing and retention in Uganda. 2. To analyse the role of school leadership and sub-national education governance mechanisms in supporting teacher wellbeing and retaining teachers in crisis-affected contexts. 3. To assess how institutionalised peer-based professional support and teacher professional development contribute to strengthening teacher wellbeing and retention in crisis-affected settings.
Uganda 2026-03-10 10:39:05 2029-03-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
KIRUNGI RICHARD
ID: UNCST-2019-R001816
A MACHINE LEARNING-BASED ANOMALY DETECTION MODEL FOR ENHANCING INTRUSION DETECTION AND PREVENTION ON UNIVERSITY NETWORK
REFNo: SIR622ES

1. To analyze and determine the challenges associated with Distributed Denial of Service and ARP-based cybersecurity threats encountered on the university network.
2. To evaluate the effectiveness of machine learning algorithms in detecting the DDoS and ARP-based cybersecurity threats identified in Objective 1, while identifying the limitations of traditional intrusion detection systems on the university network.
3. To develop a machine learning–based anomaly detection model for identifying DDoS and ARP-based threats on the university network identified in objective (1).
4. To validate the accuracy and effectiveness of the proposed machine learning–based intrusion detection and prevention model in analyzing real-time traffic on the university network.

Uganda 2026-03-10 10:43:27 2029-03-10 Engineering and Technology Non-Clinical Trial Degree Award
Fred Kyeyune
ID: UNCST-2025-R021753
Evaluating non-subtype B HIV-1 reservoirs in patients with persistent low-level viremia Populations
REFNo: HS7152ES

Objectives: Main Objective 1. The major goal of this study is to comprehensively characterize the latent HIV-1 reservoir in PLHIV who exhibit pLLV and are infected with non-subtype B viruses. 2. Estimate the inducible reservoir through envelope detection by induced transcription-based sequencing (EDITS) assay after CD4+ stimulation at baseline and 9 months. 3. Quantify cell-associated env RNA as a marker of ongoing replication at baseline and 9 months. 4. Assess reservoir clonality via near full-length sequencing and integration site analysis at baseline and 9 months. Specific Objectives 1. Determine HIV-1 subtypes and co-receptor tropism through envelope gene sequencing at baseline and 9 months. 2. Assess drug resistance evolution via proviral DNA and plasma RNA sequencing at baseline and 9 months. 3. Monitor viral load and Tenofovir (TDF) drug levels to confirm adherence and persistence of LLV at baseline and 9 months. 4. Evaluate immune status by measuring CD4/CD8 counts and markers of activation, inflammation, and exhaustion at baseline and 9 months. 5. Measure intact proviral genomes using Intact Proviral RNA Assay ( IPDA) in CD4+ cells at baseline and 9 months.
2026-03-10 10:44:52 2029-03-10 Medical and Health Sciences Non-degree Award
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