Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
raymond Kihumuro bernard
ID: UNCST-2021-R013303
Assessing the Readiness and Contextual Feasibility for Leveraging Interactive Voice Response (IVR) for Depression. Screening Among Adolescents and Young People Living with HIV in Uganda: A Formative Mixed- Methods Study
REFNo: HS7109ES

To examine stakeholder perspectives on how Interactive Voice Response (IVR) for depression screening could be integrated into the HIV care continuum.,To explore the factors influencing depression screening among adolescents and young people living with HIV (AYPLHIV).,Understand factors influencing depression screening of AYPLHIV, explore how IVR for depression screening could be integrated into the HIV care continuum.,Determine accessibility to IVR-capable phones and IVR user preferences among AYPLHIV.,
Uganda 2026-02-18 12:46:14 2029-02-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rik Lubbers
ID: UNCST-2025-R021634
Exploring Vulnerability and Resilience in Accessing and Providing Nutrition-Sensitive Maternal and Child Health Services During Floods, Droughts, and Compound Events in Katakwi, Uganda: A Multi-Hazard Qualitative Study.
REFNo: HS7019ES

To characterise how floods, droughts, and compound climate events shape vulnerability and resilience in accessing and providing nutrition-sensitive maternal and child health services in Katakwi District, Uganda. Specific objectives: To describe caregivers’ perceived access barriers and decision-making during and after floods, droughts, and compound events. To assess perceived facility-level constraints affecting continuity of maternal and child health services across referral tiers. To document household, provider, and facility-level adaptation strategies that sustain or restore services. To generate actionable, tier-specific recommendations for district preparedness and response.
Netherlands 2026-02-18 12:49:03 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Bastien Dieppois Patrice Laurent
ID: UNCST-2025-R022798
Royal Society APEX Award - Foreseeing Management of Emerging Unprecedented Hydroclimatic Extremes to Embrace Resilience in Sub-Saharan African Communities
REFNo: NS1150ES

To develop a comprehensive and transferable framework for the robust assessment and management of future hydroclimatic risks across SSA, integrating regional climate science, socio-ecological equity considerations, and long-term decision-making, using Uganda as a demonstrative case study. The research has three specific objectives (SO): [SO1] To model regional climate changes across Sub-Saharan Africa and identify plausible but unprecedented hydroclimatic extremes likely to emerge during the 21st century, with focused high-resolution climate risk assessment analysis for Uganda. [SO2] To co-identify socio-ecologically equitable adaptation priorities with Ugandan stakeholders, and to compare these insights with SSA-wide patterns captured through an online survey, thereby informing broader NbS planning frameworks. [SO3] To co-develop and evaluate long-term decision-making approaches that evaluate whether NbS benefits can be sustained in Uganda in the face of emerging unprecedented floods and droughts, with scalable implications for SSA
France 2026-02-18 12:50:40 2029-02-18 Natural Sciences Non-Clinical Trial Non-degree Award
Brenda Ogutu
ID: UNCST-2025-R021834
Understanding Community Communication and Pro-Social Engagement in Uganda: A Behavioral System Mapping Approach
REFNo: SS4873ES

This study aims to identify structural and behavioral factors (drivers, barriers, and levers) that
influence either increasing or decreasing prosocial engagement across different population
segments in Uganda, using a systems perspective. The goal is to use these insights to design
and test contextually grounded behavioral interventions that enable and empower civil
society organizations (CSOs) to influence and enhance prosocial engagement in the country.
This study will also apply the COM-B model as follows:
● Capability: Evaluating citizens' knowledge and skills to participate.
● Opportunity: Examining how access to information and spaces for engagement
either promote or hinder prosocial engagement.
● Motivation: Analyzing how beliefs, norms, and trust shape the willingness to
participate in prosocial activities.
Each research question will be aligned with the COM-B dimensions
Kenya 2026-02-18 12:56:59 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ibrahim Wanyama
ID: UNCST-2025-R017076
CIRcularity of Nutrients in AgroecoSystems and co-benefits on animal and human health (CIRNA)
REFNo: A670ES

The main objective of CIRNA is the development, assessment, and promotion of farmerapproved, lab- and field-tested manure management practices for smallholders that ensure better organic fertilizer quality, health and safety for humans, animals, and the environment, are socially inclusive and improve peoples’ livelihoods. The following are the objectives under this study Research objectives: Objective 1: To characterize manure management practices and feed basket composition in smallholder mixed crop-pig production systems in Uganda and their relationships to manure chemical and zoonotic pathogen/parasite composition. Objective 2: To determine the chemical and zoonotic pathogen/parasite composition of manure in smallholder crop-pig production systems in Uganda, and establish the relationship between manure composition and manure management practices. Objective 3: To quantify nutrient losses from selected manure management interventions in smallholder mixed crop-pig production systems through a mass balance approach and evaluate the fertilizer value of the produced manure. Objective 4: To access the performance of agricultural production, market integration, nutrition and food security, poverty, and gender across the different dimensions of sustainability using the Objective 5: To evaluate effects of selected manure management interventions on occurrence of microbial indicator species in smallholder mixed crop-pig production systems
Uganda 2026-02-20 14:11:36 2029-02-20 Agricultural Sciences Non-Clinical Trial Non-degree Award
Anacret Byamukama
ID: UNCST-2023-R007193
Prevalence and predictors of structural lung abnormalities among people with and without latent TB infection in rural Uganda
REFNo: HS3537ES

To identify potential predictive factors associated with structural lung abnormalities among people with LTBI compared to those without, exploring demographic, clinical, and environmental variables,To examine the patterns and distribution of structural lung abnormalities in adults with LTBI compared to those without, within southwestern Uganda. ,To assess the prevalence of structural lung abnormalities among people with and without LTBI in a population-based cohort within southwestern Uganda.,To examine the prevalence, patterns, distribution and predictors of structural lung abnormalities among adult people with and without latent TB infection (LTBI) within south-Western Uganda,
Uganda 2026-02-20 14:15:05 2029-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Joan Kekimuri
ID: UNCST-2025-R021625
MUJAGUZO ROYAL DRUM OF BUGANDA KINGDOM: CHRONICLES OF ITS ORIGIN, MEANING-MAKING, AND CONTINUITY
REFNo: SS4868ES

1. To document the history of the Mujaguzo royal drum. 2. To identify qualities of Mujaguzo Royal Drum as a mystical art form. 3. To disinter the rituals that encompass interregnum meaning of oral continuity from one rule to another 4. To visually interpret the mystical meaning attached to Mujaguzo royal drum through visual art.
Uganda 2026-02-20 15:08:03 2029-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
GEOFFREY OCEN
ID: UNCST-2025-R022953
Tuberculosis Treatment Outcomes and associated factors among patients receiving treatment at Dokolo HCIV, Northern Uganda
REFNo: HS7060ES

General Objective To measure Tuberculosis (TB) treatment outcomes and associated factors among patients receiving treatment at Dokolo HCIV in Northern Uganda. Specific Objectives 1.To describe the TB treatment outcomes among patient’s receiving treatment at Dokolo HCIV 2.To determine the proportion of patients achieving successful TB treatment outcomes 3.To identify Socio-demographic factors associated with TB treatment outcomes 4.To investigate the clinical factors associated with TB treatment outcomes
Uganda 2026-02-20 15:09:10 2029-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Balaamsikina Mwasa
ID: UNCST-2025-R022991
FINANCIAL MANAGEMENT REFORMS AND FINANCIAL ACCOUNTABILITY AMONG SELECTED PUBLIC SECTOR ORGANIZATIONS IN UGANDA
REFNo: SS4822ES

I. Evaluate the effect of structural financial management reforms on financial accountability in selected public sector organizations in Uganda.
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II. Assess the effect of policy-related financial management reforms on financial accountability in selected public sector organizations in Uganda.
III. Examine the effect of technological financial management reforms on financial accountability in selected public sector organizations in Uganda.
IV. Analyse the influence of audit and internal control reforms on financial accountability in selected public sector organizations in Uganda.
V. Determine the effect of revenue management reforms on financial accountability in selected public sector organizations in Uganda.
VI. Examine the moderating effect of institutional culture on the relationship between financial management reforms and financial accountability in selected public sector organizations in Uganda.
Uganda 2026-02-20 15:11:19 2029-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Ruth Kigozi Nassali
ID: UNCST-2021-R013025
Optimizing Malaria Surveillance: National-level Review of approaches, tools and interventions to inform innovative strategies for Uganda
REFNo: SS4862ES

2.1 Study Aim: • To assess the impact, experiences and outcomes of malaria surveillance interventions, approaches and tools in Uganda. 2.2 Study Objectives: • To investigate the effects of interventions, approaches and tools aimed at improving malaria surveillance system performance, data quality, and data use. • To systematically identify surveillance strengthening challenges and existing evidence-informed solutions critical for impact and provision of value for money.
Uganda 2026-02-20 15:12:21 2029-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Simon Peter Kibira Peter Sebina
ID: UNCST-2019-R000492
Evaluation of feasibility, acceptability and cost of implementing a Multiple First-line Therapies strategy for treatment of uncomplicated malaria in Uganda
REFNo: HS6995ES

1. To evaluate the process of co-design (stakeholder participation, inclusiveness, decision-making mechanisms, and alignment with policy processes). 2. To evaluate the outputs of co-design, including whether the resulting MFT models are feasible, contextually appropriate, and aligned with national policies and system capacities. 3. To implement, document and iteratively adapt MFT strategies, assessing feasibility, fidelity, acceptability and contextual adaptation across delivery settings. 4. To identify and assess the policy, supply chain, and health system factors – including stakeholder engagement – that influence implementation and decisions on scale-up across sectors. 5. To evaluate the cost, cost drivers, and overall cost impact of implementing and sustaining MFT models implemented across the four countries in diverse health system contexts.
Uganda 2026-02-20 15:16:41 2029-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mi Kyoung PARK
ID: UNCST-2025-R019313
Long-term Effectiveness of Vocational Training Programs for Ex-combatants in Post-conflict Uganda: A 20-Year Retrospective Study on Social Reintegration Impacts
REFNo: SS4015ES

To assess the long-term effectiveness of vocational training programs provided to ex-combatants in Uganda approximately 20 years after implementation, focusing on their current socio-economic status and level of social integration.
South Korea 2026-02-20 15:19:35 2029-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Byaruhanga RichardSserioza
ID: UNCST-2025-R017563
Effects, Risk Factors, and Treatment Outcomes Among Patients with Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Southwestern Uganda
REFNo: HS6938ES

1. To the impact of MDR/XDR TB on the quality of life of patients attending Mbarara, Kabale, and Fortportal Regional Referral Hospitals. 2. To establish treatment outcomes (cured, treatment completed, failure, died or lost follow-up) among MDR/XDR TB patients over a four-year period (January 2019 to December 2023) 3. To identify risk factors that predispose to MDR / XDR TB in patients from Southwestern Uganda.
Uganda 2026-02-20 15:20:40 2029-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Benjamin Wairindi
ID: UNCST-2025-R021862
The Integration of Ecological Sustainability into Refugee Self-reliance Strategies; A Case Study of Uganda
REFNo: A725ES

i. To explore the extent to which current theories and models of refugee self-reliance in Uganda incorporate ecological sustainability and identify gaps in their application. ii. To identify key ecological prerequisites and sustainable agricultural practices that support self-sufficient livelihoods for refugee and host communities. iii. To determine how nature-based solutions and ecological strategies can be integrated into Uganda’s refugee policy framework to enhance arable land utilization and regenerative livelihood outcomes. iv. To generate actionable insights from empirical findings to guide policy formulation and sustainable resource management in refugee-hosting contexts.
Uganda 2026-02-20 15:21:57 2029-02-20 Agricultural Sciences Non-Clinical Trial Degree Award
James Ochieng Robert
ID: UNCST-2025-R023203
Investigating the Vectors and non-human reservoirs for visceral Leishmaniasis in the Karamoja sub-region of Uganda
REFNo: NS1124ES

1. To identify the prevalent sand fly species and distribution in selected VL hotspot villages in the Karamoja sub-region.
2. To determine the sand fly host feeding preference within VL hotspot villages in the Karamoja sub-region.
3. To determine the prevalent rodent species in the VL hotspot villages of the Karamoja sub-region.
4. To identify the presence and species of Leishmania parasites isolated from sand flies and rodents in the Karamoja sub-region.

Uganda 2026-02-20 15:25:37 2029-02-20 Natural Sciences Non-Clinical Trial Degree Award
Anacret Byamukama
ID: UNCST-2023-R007193
Association of COPD with neurocognitive impairment and structural brain changes in people with and without HIV in Uganda
REFNo: HS7010ES

1. To characterize the relationship between COPD and structural brain changes in PWH and PWoH. 2. To characterize the relationship between COPD and NCI in PWH and PWoH. To investigate the association of chronic obstructive pulmonary disease (COPD) related structural lung abnormalities with neurocognitive impairment (NCI), and structural brain changes in PWH and people without HIV (PWoH) in Uganda
Uganda 2026-02-20 15:27:45 2029-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NKWASIBWE NELSON
ID: UNCST-2025-R023068
CAPITAL STRUCTURE AND FINANCIAL PERFORMANCE OF COMMERCIAL BANKS IN SOUTHWESTERN UGANDA
REFNo: SS4757ES

i. To determine the effect of debt financing on the financial performance of commercial banks in South Western Uganda
ii. To examine the effect of equity financing on the financial performance of commercial banks in South Western Uganda.
iii. To assess the influence of optimal financing decisions on the financial performance of commercial banks in South Western Uganda.
iv. To analyze the moderating effect of external factors on the relationship between short-term debt financing and the financial performance of commercial banks in South Western Uganda.

Uganda 2026-02-20 15:29:27 2029-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Julian Bagyendera Kobutungi
ID:
Endline Evaluation for the Second Education Response Plan (ERP II) for Refugees and Host Communities
REFNo: SS4899ES

5. To identify and document key lessons learnt and recommendations to inform future programming.,4. To assess the extent to which ERP II implementation is sustainable at national and sub-national levels,3. To analyse the efficiency of ERP II implementation, including resource utilisation and process management.,2. To assess the effectiveness of ERP II implementation with a specific focus on progress made in executing planned activities and delivering outputs in alignment with ERP II objectives.,1. To evaluate the relevance and coherence of interventions in addressing beneficiaries’ needs and priorities, and the level of complementarity, harmonisation, and coordination among actors.,To assess the overall performance in achieving its intended outcomes.,
Uganda 2026-02-23 12:58:30 2029-02-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
Infant Sleep Positioning in Uganda: Formative Research to Inform Culturally Appropriate Sudden Infant Death Syndrome (SIDS) Prevention Strategies
REFNo: HS7148ES

1. To explore caregivers’ beliefs, social norms, and perceived control regarding infant sleeping position practices in the north and central regions of Uganda. 2. To identify cultural, social, environmental, and structural barriers and facilitators of the adoption of supine sleeping for infants. 3. To adapt key components and messages of the “Back to Sleep” campaign for the Ugandan context. 4. To assess the acceptability and feasibility of using an objective device to measure infant sleeping position in preparation for a future sleep position intervention study.
Uganda 2026-03-03 12:20:23 2029-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ZALIKA FIKIRA
ID: UNCST-2025-R022860
Internal Control Systems and Management of Accounts Receivables in Private Healthcare Providers in Uganda: A Case of Norvik Hospital, Kampala
REFNo: SS4893ES

To examine the relationship between Control environment and Management of accounts receivables in private healthcare providers in Uganda, a case of Norvik Hospital. To examine the relationship between Monitoring activities and Management of accounts receivables in private healthcare providers in Uganda, a case of Norvik Hospital. To examine the relationship between Control activities and Management of accounts receivables in private healthcare providers in Uganda, a case of Norvik Hospital.
Uganda 2026-03-03 12:21:34 2029-03-03 Social Science and Humanities Non-Clinical Trial Degree Award
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