Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Kizito Wamala
ID: UNCST-2025-R018261
Exploring the Traditional Counseling Practices of Indigenous Community Practitioners Treating Psychological Distress in Victims of Intimate Partner Violence in Uganda: A Case of Buganda
REFNo: SS4703ES

1.To explore the practices of traditional counseling offered by the indigenous community practitioners treating psychological distress in victims of intimate partner violence in Buganda.

2.To explore the experiences of indigenous community practitioners offering traditional counseling for treating psychological distress in victims of intimate partner violence in Buganda.

3.To derive the worldview that underpins the traditional counseling practices of indigenous community practitioners treating psychological distress in victims of intimate partner violence in Buganda.
Uganda 2026-02-12 13:29:36 2029-02-12 Social Science and Humanities Non-Clinical Trial Degree Award
EUGENE ARINAITWE -
ID: UNCST-2023-R005572
SEROLOGICAL AND MOLECULAR EPIDEMIOLOGY OF RIFT VALLEY FEVER VIRUS IN LIVESTOCK FROM THE SELECTED DISTRICTS OF UGANDA
REFNo: NS1079ES

General objective:
To understand the epidemiology of the circulating RVFv strains in the selected districts of the Uganda cattle corridor and establish the distribution and the trend of RVF outbreaks in Uganda in the past 10 years

Specific Objectives:
1. To establish the distribution and the trend of RVF outbreaks in Uganda in the past 10 years (2013-2022)
2. To determine the seroprevalence of Rift Valley Fever (RVF) in livestock from selected districts of the Uganda cattle corridor
3. To establish the associated risk factors of RVF among the livestock farmers from selected districts of the Uganda cattle corridor
4. To determine the Knowledge, Attitudes, and Practices of pastoralists from selected districts of the Uganda cattle corridor towards Rift Valley Fever
5. To establish genetic diversity of RVF viruses circulating within the livestock in the Uganda cattle corridor

Uganda 2026-02-12 13:32:15 2029-02-12 Natural Sciences Non-Clinical Trial Degree Award
Patrick Omiel Okecho
ID: UNCST-2025-R019368
Socio-Technical Factors Shaping the Integration of Climate Services into the Health System: A Case Study of Uganda’s DHIS2 Platform
REFNo: SS4764ES

Main objectives:
To examine the socio-technical factors that influence the integration of climate services into Uganda’s health information system through the DHIS2 platform.

To document how actors build legitimacy and foster cross-sectoral collaboration for climate service integration through the DHIS2 platform.

To analyze how climate services are embedded into routine HIS workflows through the DHIS2 platform.

To examine how climate-informed early warning practices f

Uganda 2026-02-12 13:33:16 2029-02-12 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Lukenge
ID: UNCST-2025-R021961
INFRASTRUCTURE QUALITY AND STUDENT’S SATISFACTION MEDIATED BY SENSE OF CAMPUS COMMUNITY IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS4520ES

This proposed study seeks to investigate the influence of infrastructure quality on the satisfaction of students mediated by a sense of campus community at public universities in Uganda.
Uganda 2026-02-12 13:35:38 2029-02-12 Social Science and Humanities Non-Clinical Trial Degree Award
Crispus Tashobya
ID: UNCST-2025-R022506
INTELLECTUAL CAPITAL AND BUSINESS PERFORMANCE AMONG SMALL & MEDIUM ENTERPRISES (SMEs) IN AGRO-FOOD PROCESSING IN WESTERN UGANDA
REFNo: SS4810ES

i. To assess the effect of structural capital on business performance of agro-food processing SMEs in Western Uganda.
ii. To determine the effect of human capital on business performance of agro-food processing SMEs in Western Uganda.
iii. To analyze the effect of relational capital on business performance of agro-food processing SMEs in Western Uganda.
iv. To examine the mediating effect of innovation on the relationship between intellectual capital and business performance of agro-food processing SMEs in Western Uganda.

Uganda 2026-02-12 13:38:44 2029-02-12 Social Science and Humanities Non-Clinical Trial Degree Award
SHAFIGA BABIRYE
ID: UNCST-2024-R004302
Prevalence and factors associated with traditional medicine use among patients scheduled for surgery at Kyabirwa surgical center, Budondo sub-county-Jinja city
REFNo: HS7012ES

1. To determine the prevalence of traditional medicine use among patients scheduled for surgery at Kyabirwa Surgical Center, Budondo sub-county, Jinja city 2. To assess the factors associated with traditional medicine use among patients scheduled for surgery at Kyabirwa Surgical Center, Budondo sub county, Jinja city
Uganda 2026-02-12 13:40:07 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victoria Rutter N/A
ID: UNCST-2025-R019210
Alignment of Fleming Fund’s Organisational Structure and Strategic Approach to Sustainable, Country-Led AMR Programme Delivery
REFNo: HS6774ES

Aim: To assess whether Fleming Fund’s current organisational structure and strategies effectively support sustainable, country-led AMR interventions. Specific objectives: 1. Evaluate how FF’s organisational structure aligns with its increasing focus on supporting sustainable, country-led AMR initiatives. 2. Examine the alignment of the Fleming Fund’s approach to national health priorities. 3. Assess factors affecting the sustainability of Fleming Fund-funded AMR programmes
UK 2026-02-12 13:40:57 2029-02-12 Medical and Health Sciences Non-Clinical Trial Degree Award
MARTHA GIMONO
ID: UNCST-2024-R016208
Improving Glycemic Control, Knowledge and Self-Management Practices Through Educational Curriculum for Young Adults with Type 1 diabetes in low-resource settings
REFNo: HS6947ES

1. To assess the changes in participants' diabetes knowledge, glycemic control, and self-management practices before and after participation in the Warrior Educator Training Program. 2. To evaluate the effectiveness of trained peer- educators in supporting Type 1 Diabetes (T1D) clinic operations and patient outcomes. 3. To assess the feasibility and impact of implementing the Warrior Educator Training Program in low resource settings.
Uganda 2026-02-12 13:41:51 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
Impact of pregnancy on HIV reservoir activity, and associated immune dynamics, inducibility, and clonality
REFNo: HS7025ES

Test the impact of pregnancy on immune dynamics and HIV reservoir activity, inducibility, and clonality.
Uganda 2026-02-12 13:43:01 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Leah Mbabazi
ID: UNCST-2019-R000099
Factors associated with malaria vaccine uptake among caregivers of children under five years in North-Western Uganda
REFNo: HS6997ES

Primary objective: To assess the factors associated with malaria vaccine
uptake among caregivers of children under five years in North Western
Uganda.
Secondary objectives:
1. To determine the Malaria vaccine uptake level among
caregivers of children under five years in North-Western
Uganda.
2. To determine factors influencing malaria vaccine uptake
among caregivers of children under five years in North
Western Uganda.
3. To assess the attitudes and perceptions of the caregivers
towards the malaria vaccine in North-Western Uganda.
4. To assess care giver and health care provider experiences and
practices that influence malaria vaccination in North-Western
Uganda.
Uganda 2026-02-18 12:09:39 2029-02-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abias Asiimwe Katesigwa
ID: UNCST-2025-R022247
Quality Improvement Strategies in Private Healthcare Facilities in Uganda
REFNo: HS7033ES

General Objective:
The primary purpose of this study is to investigate how Quality Improvement (QI) strategies become institutionalised within Uganda's private health facilities, examining the processes, factors, and outcomes that enable QI practices to transition from externally-driven initiatives to internally-sustained organisational norms.
Specific Objectives:
1. To identify and evaluate Quality Improvement (QI) strategies employed by private health facilities to enhance care quality.
2. To analyse the processes and critical factors influencing the institutionalisation of QI initiatives as a cultural norm within private health facilities, including challenges and strategies for their mitigation.
3. To assess the return on investment (ROI) of QI initiatives, focusing on their impact on care quality and operational efficiency in private health facilities.
4. To explore patients' perceptions and experiences regarding the quality of health services delivered by private health facilities.
5. To develop strategic recommendations for the institutionalisation of Quality Improvement (QI) initiatives within healthcare systems and to enhance care quality in the private health sector, informed by expert review and validation.

Uganda 2026-02-18 12:12:04 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Natalia Marina Maure Marina
ID: UNCST-2024-R003148
Burden of cardiovascular disease risk factors among patients with tuberculosis in the karamoja sub-region of uganda. A cross-sectional survey
REFNo: HS6547ES

Primary objective: •Estimate the burden of CVD risk factors among TB patients at Matany and Moroto hospitals Secondary objectives: •Compare the burden of CVD risk factors between TB patients at Matany and Moroto hospitals and the burden of CVD risk factors in the Ugandan general population •Contrast the burden of CVD risk factors among TB inpatients and outpatients •Secondary Endpoint 2: Prevalence of CVD risk factors in TB inpatients and outpatients •Determine the 10-year cardiovascular event risk using the WHO/ISH risk prediction charts •Describe the associations between TB disease characteristics (pulmonary vs. extrapulmonary, drug-resistant vs. drug-susceptible, HIV co-infection status) and cardiovascular risk profiles
Italy 2026-02-18 12:13:03 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
LONG TERM CARDIAC AND PULMONARY CONSEQUENCES OF TB (LONG TB)
REFNo: HS6945ES

Establish a sample repository for future: a) host and M.tb whole genome sequencing for genome wide association studies, b) non-targeted multi-omic (transcriptome, proteome, metabolome) analysis and, c) targeted inflammatory/immunological pathway analysis,Characterize the prevalence, clinical presentation, and progression of sub-clinical CVD – a surrogate measure for subsequent PTCVD risk – among successfully treated adult drug-sensitive pulmonary TB cases,Characterize the prevalence, clinical presentation, and progression of PTLD among successfully treated adult drug-sensitive pulmonary TB cases,The overarching goal of this proposal is to establish a well characterized cohort of pulmonary TB patients with prospective cardio-pulmonary assessments and sample repository during and after treatment for comprehensive clinical phenotyping and immunological endotyping of post-TB sequelae,
Uganda 2026-02-18 12:14:31 2029-02-18 Medical and Health Sciences Non-degree Award
Bernard Mwesigye
ID: UNCST-2024-R016003
Delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emmergency Unit of Mbarara Regional Referral Hospital
REFNo: HS6376ES

General:To assess the proportion of patients with delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emergency Unit at Mbarara Regional Referral Hospital.
Specific objectives:
•To determine the proportion of high acuity patients with delayed Door-to-Doctor time at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.
●To determine the factors associated with delayed Door-to-Doctor time of high acuity patients at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.

Uganda 2026-02-18 12:16:08 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Mark Jordans
ID: UNCST-2020-R014861
MENTAL HEALTH SYSTEMS AND A MENTAL HEALTH CARE PACKAGE FOR CHILDREN IN SELECTED REFUGEE SETTLEMENTS IN UGANDA (PAMOJA TUNAWEZA): PARTICIPATORY SYSTEM DYNAMICS AND CLIENT JOURNEYS
REFNo: SS4795ES

Objectives: 
This study aims to identify and evaluate key factors affecting the implementation and performance of a mental health care system in real-world settings.
Specific Research objectives and research questions:
1. To assess how well the mental health care system integrates and is compatible with existing mental healthcare services, infrastructure, and practices, both formal and informal with a particular focus on adolescent mental health.  
Research Question 1: Exploring how the mental health care system integrates, or is compatible, with existing mental health systems for adolescent mental health

2. To examine client experiences within the care system and identify opportunities to optimize service delivery and outcome.
Research Question 2: Evaluating the client experience, how this can be optimized within the care system

Netherlands 2026-02-18 12:19:41 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
moiti MoitiEriya
ID: UNCST-2024-R016141
LIFE HISTORY TRAITS OF VARROA MITE (Varroa destructor) AND ITS EFFECT ON HONEYBEE COLONY PERFORMANCE IN SELECTED AGRO-ECOLOGICAL ZONES IN UGANDA
REFNo: NS1167ES

To determine the effect of Varroa infestation levels on colony performance of Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess the effect of honeybee hygienic behavior and swarming behaviour on Varroa infestation levels in Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess life history traits of Varroa mites infesting Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess temporal Varroa infestation levels in Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To evaluate Varroa reproductive success so that its impact on honeybee colony performance is established.,
Uganda 2026-02-18 12:20:50 2029-02-18 Natural Sciences Non-Clinical Trial Degree Award
DAVID KITYA
ID: UNCST-2022-R009620
Quality of life in postoperative neurosurgical patients: decompressive hemicraniectomy with delayed cranioplasty versus hinge craniotomy in low-resource settings
REFNo: HS6653ES

Provide Recommendations: Develop evidence-based guidelines for surgical practices in resource-limited settings, prioritizing interventions that optimize long-term QoL,Analyze Contextual Factors: Identify patient and caregiver demographic and clinical factors influencing QoL outcomes.,Evaluate Caregiver Impact: Examine how the two surgical interventions affect caregiver QoL, including their psychological well-being and caregiving burden.,Assess QoL: Use modifications of validated surveys (e.g., Neuro-QoL surveys) to evaluate physical, cognitive, emotional, and social QoL outcomes in patients.,To compare and evaluate the long-term QoL outcomes of patients undergoing DHC without cranioplasty and HC, focusing on physical, cognitive, emotional, and social domains, as well as the perspectives of their caregivers​.,
Uganda 2026-02-18 12:22:28 2029-02-18 Medical and Health Sciences Non-degree Award
raymond Kihumuro bernard
ID: UNCST-2021-R013303
Depression Assessment in Adolescents and Young People Living with HIV in Uganda using Interactive Voice Response (DAIVR): A Pilot Feasibility Study
REFNo: HS7107ES

2. Evaluate the feasibility, acceptability, performance, and screening yield of DAIVR.,1. Explore healthcare workers’ (HCW) and AYPLHIV’s preparedness for integrating IVR-based PHQ-2 screening into routine care.,
Uganda 2026-02-18 12:28:27 2029-02-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martin Okello
ID: UNCST-2025-R020344
INVESTIGATION OF PLANT-BASED MOSQUITO REPELLENTS FOR VECTOR-BORNE DISEASE CONTROL, ESPECIALLY MALARIA IN RURAL UGANDA: A MIXED METHODS APPROACH
REFNo: HS7051ES

4. To gain more understanding through existing literature/research about Lantana camara (LC) plants and other repellent/herbal plants in relations to vector borne diseases, especially malaria control/prevention in rural Uganda.
5. To collect information regarding attitude, knowledge, beliefs, and behaviours about Lantana camara (LC) plants and possibly other repellent plants in relation to malaria prevention in rural Uganda.
6. To explore factors associated with implementing the use of plant-based repellent products like Lantana plant extracts or other repellant plants as alternatives to control or prevent malaria in rural Uganda, including the feasibility, acceptability and sustainability of such approaches.

Uganda 2026-02-18 12:32:51 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Deborah Kirabo
ID: UNCST-2025-R022547
Documentation of RAHU Peer Education Model
REFNo: SS4727ES

Objective 1: To comprehensively document RAHU\'s Peer Education Model design, implementation mechanisms, and operational approaches across five regions (Kampala, Kasese, Adjumani, Busoga, and Sebei) from 2014 to present

Objective 2: To assess the peer education model\'s performance against its three core program objectives: (a) improving young people\'s access to SRHR information for informed decision-making, (b) reducing risks and promoting individual and collective empowerment about sexual and reproductive health, and (c) strengthening interpersonal communication skills for peer-to-peer SRHR communication

Objective 3: To analyze implementation challenges, success factors, regional adaptations, and lessons learned to generate evidence-based recommendations for model replication, scaling, and policy advocacy.
Uganda 2026-02-18 12:43:08 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
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