JIMMY SSEMALULU
ID:
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PRESCRIPTION PRACTICES AND USE OF LABORATORY PARAMETERS TO MONITOR EFFICACY AND TOXICITY OF ANTIRETROVIRAL THERAPY (ART) AMONG HIV PATIENTS (15YEARS AND ABOVE) AT ART CLINIC IN BUTABIKA NATIONAL PSYCHIATRIC REFERRAL HOSPITAL, UGANDA.
REFNo: HS151ES
STUDY OBJECTIVES
General objective
To assess prescription practices and use of laboratory parameters to monitor efficacy and toxicity of ART among HIV patients (15 years and above) at ART clinic in Butabika hospital.
1.5.2 Specific objectives
1. To describe pharmaceuticals prescribed for HIV patients (15 years and above) at ART clinic in Butabika hospital.
2. To determine drug drug interactions between ARVs and other medicines prescribed to HIV patients (15 years and above) at ART clinic in Butabika hospital.
3. To identify laboratory parameters used to monitor treatment response and toxicity of ARVs among HIV patients (15 years and above) on ART in Butabika hospital.
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Uganda |
2018-04-11 |
2021-04-11 |
Medical and Health Sciences |
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Degree Award |
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Laura Bogart
ID:
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GAME CHANGERS: A PILOT INTERVENTION TO EMPOWER HIV CLIENTS AS PREVENTION ADVOCATES IN UGANDA (PHASE 2)
REFNo: SS166ES
Primary objectives include: Assessing preliminary intervention effects on:
a) protective behavior of the HIV-positive clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART adherence)
b) diffusion of prevention messages across the network, as assessed by the content and extent of communication with network members about protective behaviors (condom use, partner concurrency/number of partners, HIV testing, engagement in HIV care, circumcision), HIV disclosure, and HIV stigma
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USA |
2018-04-11 |
2021-04-11 |
Social Science and Humanities |
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Non-degree Award |
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Michael Carter Ross
ID:
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Smallholder Farmers’ Returns and Learning from Subsidized Inputs in Uganda
REFNo: SS145ES
The Government of Uganda is launching an agricultural input subsidy program through an electronic voucher and we have the opportunity to study its first implementation phase (5,000 households) and provide lessons for scaling up the full program (450,000 households) by evaluating, inter alia, how different subsidy schemes affect the spread of technology to poor households and their networks and women farmers and their networks.
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USA |
2018-04-20 |
2021-04-20 |
Social Science and Humanities |
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Non-degree Award |
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Jacent Kamuntu Asiimwe Kamuntu
ID:
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BASELINE ASSESSMENT OF KNOWLEDGE, ATTITUDES AND PRACTICES ON HEALTH AND NUTRITION AMONG CAREGIVERS AND PREGNANT WOMEN IN LIVING GOODS OPERATIONAL DISTRICTS
REFNo: HS192ES
To assess and document existing knowledge, attitudes and practices of caregivers and pregnant women in Living Goods’ areas of operation on, nutrition and other health seeking behaviour during pregnancy as well as infant and young child feeding – (IYCF) practices.
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Uganda |
2018-04-20 |
2021-04-20 |
Medical and Health Sciences |
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Non-degree Award |
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Mael Leroux
ID:
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Dual articulation in the communication system of chimpanzees
REFNo: NS47ES
The emergence of combinatoriality (phonology and syntax) in human language represents one of the key evolutionary transitions in life (Maynard Smith & Szathmary 1995). Despite its significance, we know very little regarding how unique this capacity is to humans or the evolutionary progression of this trait. By searching for core features of language, such as its combinatoriality, in the communication systems of closely related species to humans, particularly the primates, it is possible to shed light on whether the components of language are de novo evolved traits in humans or whether they have their origins rooted in the primate lineage.
With this project, I aim to shed light on how unique combinatorics is to human language through empirically investigating the presence of linguistic forms of phonology and syntax in our closest living relative, the chimpanzee.
|
France |
2018-04-20 |
2021-04-20 |
Natural Sciences |
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Degree Award |
|
Simon Wakwale Peter
ID:
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POLITICAL DECENTRALISATION AND LOCAL GOVERNMENT PERFORMANCE: A CASE STUDY OF MBALE MUNICIPAL COUNCIL
REFNo: SS76ES
1. TO EXAMINE THE EFFECT OF DEVOLUTION OF POWERS ON TIMELY ACCOUNTABILITY IN MBALE MUNICIPAL COUNCIL
2. TO ASSESS THE EFFECT OF DEVOLUTION OF POWERS ON INFRASTRUCTURAL DEVELOPMENT IN MBALE MUNICIPAL COUNCIL
3. TO ESTABLISH THE EFFECT OF DEVOLUTION OF POWERS ON PROVISION OF SOCIAL SERVICES IN MBALE MUNICIPAL COUNCIL
4. TO FIND OUT THE EFFECT OF DEVOLUTION OF POWERS ON POLICY IMPLEMENTATION IN MBALE MUNICIPAL COUNCIL
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Uganda |
2018-04-24 |
2021-04-24 |
Social Science and Humanities |
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Degree Award |
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CHRISTOPHER OPIO KENNETH
ID:
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Analysis of the genetic determinism of hepatocellular carcinoma (HCC)
REFNo: HS125ES
1) Determine the association between chosen genetic markers among patients with HCC compared with subjects from Uganda with advanced liver fibrosis (F4 or cirrhosis). 2) Explore additional genetic markers of HCC by selected sequencing (targeted sequencing and exome sequencing) of the genome of subjects with HCC compared to controls from Uganda. 3) Determine whether these markers correlate with the clinical stages of HCC and could be predictive of HCC progression. 4) To describe clinical outcomes of advanced liver fibrosis (F4 or cirrhosis) or HCC over the study follow-up period.
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Uganda |
2018-04-24 |
2021-04-24 |
Medical and Health Sciences |
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Non-degree Award |
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Tiffany Basciano Nicole
ID:
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No One Left Behind? A Study on the Human Rights of Women Living With HIV/AIDS in Uganda
REFNo: SS140ES
A study on adult women living with HIV/AIDS in Uganda. The study will include an examination of how women’s rights are integrated into HIV/AIDS-related laws, policies, programs, and initiatives in Uganda. We will further examine any challenges that women may face in family life, healthcare settings, or in the workplace because of their status, as well as any distinction in the experiences of women in urban versus rural settings. We hope that this research will help support the achievement of Sustainable Development Goals (SDGs) 3 – good health and well-being and 5 gender equality.
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USA |
2018-04-24 |
2021-04-24 |
Social Science and Humanities |
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Degree Award |
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Specioza Twinamasiko
ID:
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Oil discovery and compensation over land: Conceptualizing risks and vulnerabilities of women's household livelihoods i Albertine Graben, Uganda
REFNo: SS147ES
i- To discover the nature of oil related land contestations in the Albertine Graben.
ii- To explore the risks and vulnerabilities experienced by women after oil discovery.
iii- To examine land compensation processes before and after eviction.
iv- To Explore the role of women in the land compensation process.
v- To examine the strategies women have put in place to improve their livelihood.
|
Uganda |
2018-04-24 |
2021-04-24 |
Social Science and Humanities |
|
Degree Award |
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Richard Wamimbi Wotti
ID:
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Community Systems and Practices to Prevent and Respond to Violence Against Children in Uganda: Children's perceptions and lived experiences.
REFNo: SS158ES
1.Find out the perceptions and lived experiences of children most especially girls in preventing and responding to Violence Against Children in their communities.
2.Establish what the formal (education and social welfare) and non formal (family , faith based, traditional) approaches to child protection are and how they are being applied in creating safer communities in Uganda free from violence.
3.Examine how the formal and non-formal elements of community referral and reporting mechanisms are functioning to prevent and respond to Violence Against Children.
4.Explore how girls are affected by different forms of violence and how they are supported to enable them live in an environment that is free from all forms of violence throughout their life course
|
Uganda |
2018-04-24 |
2021-04-24 |
Social Science and Humanities |
|
Degree Award |
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Wilfred Kokas Aupal Kokas
ID:
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Change Management Practices and Performance of Selected Local Governments in Eastern Uganda
REFNo: SS165ES
1. To establish the relationship between executive support and performance of selected Local Governments in Eastern Uganda.
2. To assess the relationship between effective communication and performance of selected Local Governments in Eastern Uganda.
3. To investigate the relationship between employee involvement and performance of selected Local Governments in Eastern Uganda
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Uganda |
2018-04-24 |
2021-04-24 |
Social Science and Humanities |
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Degree Award |
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Jack Horowitz Rosengarten
ID:
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Community-Driven Financial Solutions to Human-Wildlife Conflict in Uganda's Albertine Rift Eco-Region
REFNo: SS176ES
1. Policy objective:
Uncover and clearly illustrate any institutional challenges of the Human-Wildlife Conflict Resilience Fund (HWCRF) project that may exist which are unique to Uganda’s Albertine rift region (UAR) in order to (a) strengthen the long-term implementation of the HWCRF project and (b) provide lessons learned for other governments and communities looking to implement human-wildlife conflict (HWC) financial instruments within similar geographies.
2. Academic objective:
Contribute to the literature by bridging HWC insurance research outside of Sub-Saharan Africa with previous studies on HWC within UAR which have yet to formally analyze HWC financial instruments.
|
USA |
2018-04-25 |
2021-04-25 |
Social Science and Humanities |
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Degree Award |
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Pakoyo Kamba Fadhiru
ID:
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Elucidating the mechanism of interaction of mycobacteria rhomboid proteases with their specific substrates
REFNo: NS49ES
The goal is to elucidate the mechanism(s) of interaction of mycobacteria rhomboid proteases with their specific native substrates. There are three specific objectives:
• To identify the native peptide substrates for mycobacteria rhomboid proteases.
• To elucidate the substrate residues essential in interaction with mycobacteria rhomboid proteases.
• To elucidate the mycobacteria rhomboid protease residues essential in interaction with their substrates.
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Uganda |
2018-04-30 |
2021-04-30 |
Natural Sciences |
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Non-degree Award |
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Andrea Calcagno
ID:
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Using Calcaneal Quantitative Ultrasound (cQUS) and urine Retinol Binding Protein to screen HIV-infected cART-treated patients for reduced bone mineral density: a pilot study
REFNo: HS204ES
Primary objective: To compare DEXA and cQUS in predicting reduced BMD in a population of Ugandan HIV-infected individuals on long-term cART.
Secondary objective: To assess the prevalence of abnormal RBP/Cr and the correlation between abnormal RBP/Cr and reduced BMD.
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Italy |
2018-04-30 |
2021-04-30 |
Medical and Health Sciences |
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Non-degree Award |
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Michael Juma
ID:
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EXAMINING THE EFFECT OF SERVICE DELIVERY FACTORS ON TIMELY INITIATION OF TUBERCULOSIS TREATMENT WITHIN PRIMARY CARE SETTINGS IN UGANDA
REFNo: HS205ES
The study goal is to examine the association between service delivery factors and timeliness of Tuberculosis treatment initiation within accredited primary care facilities in Uganda. Here service delivery factors are characteristics relating to HF structure and care delivery.
The specific aims are:
Aim 1: To explore the association between service-delivery factors (structural and care delivery characteristics) and process timeliness (diagnosis time, laboratory turnaround time and treatment initiation time)
Aim 2: To measure the association between process timeliness and Tuberculosis treatment initiation
Aim 3: Describe perspectives of healthcare workers (in-charges of outpatient departments, heads of clinical teams and heads of laboratories) within each accredited health facility on preventing delays in diagnosis and initiation of Tuberculosis treatment.
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Uganda |
2018-04-30 |
2021-04-30 |
Medical and Health Sciences |
|
Degree Award |
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Sylvia Nabukenya
ID: UNCST-2019-R000906
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ASSESSMENT OF THE INFORMED CONSENT PROCESS FOR STUDIES INVOLVING GENETIC RESEARCH AMONG PEOPLE LIVING WITH HIV AT THE INFECTIOUS DISEASES INSTITUTE (IDI)
REFNo: HS199ES
1. To assess the adequacy of informed consent documents used for pharmacogenetic research and the collection, storage and future use of human samples.
2. To determine the methods used by researchers to ensure research participants’ understanding during the informed consent process in pharmacogenetic research.
3. To assess the factors that influence participants’ understanding during the consent process in pharmacogenetic research
|
Uganda |
2018-05-04 |
2021-05-04 |
Medical and Health Sciences |
|
Degree Award |
|
Jenna Wozniak Marie
ID:
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Community Knowledge, Attitudes, and Practices Around Individual Blackfly Control and the Diseases They Transmit in Northern Uganda
REFNo: HS200ES
The objective of this research project is to determine what individual level control efforts are being used to protect against blackfly biting within communities. Although large-scale control efforts have been implemented in onchocerciasis endemic regions, individual level control efforts are not well recorded or understood. Through the use of a KAP (knowledge, attitudes, and practices) survey it is hoped that this will be understood. Demographic data will also be collected to find correlations between knowledge and education level. Future application of this information can be used to either modify existing methods or to suggest personal control methods for communities where onchocerciasis and nodding syndrome are endemic. This project will take place in the district of Kitgum and Lamwo in northern Uganda were both onchocerciasis and nodding syndrome have been observed. Over a five-week period, I will travel to several communities within each district to conduct my survey. The research question of this project is what do individuals in communities where onchocerciasis and nodding syndrome are observed know as well as perceive about blackflies and what practices do they use to prevent blackfly biting?
|
USA |
2018-05-04 |
2021-05-04 |
Medical and Health Sciences |
|
Degree Award |
|
Fiona Cresswell
ID:
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High dose oral and intravenous rifampicin for adult tuberculous meningitis: an open-label phase II randomised controlled trial
REFNo: HS136ES
1. To determine whether higher-dose rifampicin, delivered orally at 35mg/kg/day or delivered intravenously at 20 mg/kg/day (for 2-weeks, followed by orally at 35 mg/kg/day for 6-weeks) provide equivalent plasma and CSF exposures, and whether the exposure profiles are favourable compared to the standard dose oral rifampicin. The pharmacokinetically optimal dose and route of administration of rifampicin can then be taken forward into a phase III clinical trial.
2. To observe whether greater rifampicin exposure in CSF is associated with any clinical benefit including more rapid resolution of coma, reduced neurocognitive deficit or reduced mortality.
3. To determine the diagnostic accuracy of Xpert MTB/Rif Ultra for TBM (ancillary study 1)
4. To describe the concentration of rifampicin in brain tissue in each treatment arm (ancillary study 2)
5. To explore the use of bedside ultrasound as a monitoring tool to improve supportive care for people with TBM (ancillary study 3)
|
UK |
2018-05-15 |
2021-05-15 |
Medical and Health Sciences |
|
Degree Award |
|
Moses Ocan
ID: UNCST-2020-R014731
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Antimalarial resistance in Sub-Saharan Africa: Assessing spread of artemisinin resistance and chloroquine resistance reversal among Plasmodium falciparum parasites
REFNo: HS168ES
1) To determine through a systematic review, the extent of chloroquine resistance reversal among Plasmodium falciparum parasites in malaria endemic countries since the change in policy
2) To determine the association between four (4) most reported K13 gene polymorphisms in Sub-Saharan Africa and artemisinin susceptibility among Plasmodium parasites
3) To predict using a model the spread to Sub-Sahara African (Uganda) Plasmodium falciparum parasite population of the K13 propeller gene polymorphisms detected in Southeast Asia and associated with artemisinin resistance
|
Uganda |
2018-05-15 |
2021-05-15 |
Medical and Health Sciences |
|
Degree Award |
|
Kirsten Ward
ID:
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Evaluation of delivery practices for multiple vaccines at a single immunization visit in low- and middle-income countries Uganda
REFNo: HS170ES
Aim: This evaluation aims to describe current preparation, administration and communication practices in the delivery of more than one vaccine to a single child at a single immunization visit in Uganda.
Objectives: 1. To document the processes and techniques used to prepare and administer more than one vaccine, primarily injectable vaccines, to children in Uganda;
2. To understand the timing, content, and extent of communication messages about co-administration of one or more vaccines and post-vaccination care delivered by providers to caregivers in Uganda; and
3. To use results from 1 & 2 to develop recommendations about best practices for: a) the preparation and delivery of multiple vaccines with a focus on injectable vaccines, and b) provider communication to the caregiver about delivery of multiple vaccines and post-vaccination care.
|
Australia |
2018-05-15 |
2021-05-15 |
Medical and Health Sciences |
|
Non-degree Award |
|
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