Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Winifred Kayizzi Nimukunda
ID:
University governance and research performance in selected public universities in Uganda
REFNo: SS1952ES

The research is to investigate the relationship between university governance and research performance of public universities in Uganda,To examine the impact of participation by university stakeholders in governance decision making processes on research performance of public universities in Uganda.,To investigate the academic governance practices impact on research performance of public universities in Uganda.. ,To establish the effect of governance architecture on research performance of public universities.,
Uganda 2023-12-19 11:16:13 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Winfred  Tugumisirize
ID:
Participatory Budgeting and Financial Sustainability in the Local Government in Uganda: A Case Study of Kabale District
REFNo: SS2353ES

4. To establish the relationship between participatory budgeting and financial sustainability in Kabale District Local Government.,3. To assess the relationship between budget implementation and financial sustainability in Kabale District Local Government.,2. To analyze the impact of budget approval on financial sustainability in Kabale District Local Government.,1. To examine the influence of budget formulation on financial sustainability in Kabale District Local Government . ,The main objective of the study is to examine the relationship between participatory budgeting and financial sustainability of Local Governments in Uganda.,
Uganda 2024-02-26 13:47:53 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
WINFRED NANNOZI
ID: UNCST-2024-R004301
PREVALENCE AND FACTORS ASSOCIATED WITH TOMOPHOBIA AMONG PRE-OPERATIVE PATIENTS AT KYABIRYA SURGICAL CENTER, BUDONDO SUB-COUNTY, JINJA CITY
REFNo: HS5857ES

To establish the institutional predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the patient-related predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To determine the prevalence of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,
Uganda 2025-08-18 12:53:37 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WINFRED ARINAITWE
ID: UNCST-2024-R015869
DEVELOPMENT OF A SECURITY FRAMEWORK FOR INFORMATION SHARING-ENABLED INTERNET OF MEDICAL THINGS IN SELECTED HEALTH INSTITUTIONS IN UGANDA
REFNo: SIR480ES

(i) To study existing security frameworks used in Information Sharing IoMT-compatible devices and applications.
(ii) To establish requirements for designing a security framework specific to the needs of Information Sharing-Enabled IoMT systems in selected Ugandan health institutions.
(iii) To develop a tailored security framework for Information Sharing-Enabled Internet of Medical Things.
(iv) To validate the developed Security Framework for Information Sharing-Enabled Internet of Medical Things.

Uganda 2025-07-18 14:10:11 2028-07-18 Engineering and Technology Non-Clinical Trial Degree Award
Wilson Namuwoza
ID:
Adoption framework for Digital Utilization in Banking in Resource Constrained Environments
REFNo: SS2411ES

The general Objective is to develop an adoption framework for digital utilization in banking in resource constrained environments.
While the Specific Objectives are;
1. To examine the digital products and technologies currently being used by commercial banks.
2. To assess the barriers and facilitators for the current use of commercial bank digital products and technologies.
3. To design a framework that can support digital utilisation in banking in resource constrained environments.
4. To test and validate the designed framework that can support digital utilization in banking in resource constrained environments.

Uganda 2024-03-14 18:44:34 2027-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
willy waninga
ID:
THE INCORPORATION OF ICT AND GENDER IN THE TEACHING OF PHYSICS EDUCATION IN TEACHER TRAINING INSTITUTIONS IN EASTERN UGANDA
REFNo: SS1891ES

1. To investigate physics lectures’ ICT competence levels (Technological content knowledge) in TTIs in Eastern Uganda.
2. To find out ICT application or tools used by lecturers in teaching Physics Education in TTIs in Eastern Uganda.
3. To examine the different factors which impede the lecturer’s use of ICT in the teaching of physics Education in TTIs in Eastern Uganda.
4. To find out ICT competences possessed by physics student teachers by gender in TTIs in Eastern Uganda.
5. To compare the ability of students in using ICT to enhance their achievement in physics by gender in TTIs in Eastern Uganda.

Uganda 2023-10-04 21:56:08 2026-10-04 Social Science and Humanities Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
PERFORMANCE OF ALTERNATIVE MEASURES OF RESPONSE TO THERAPY DURING THE INITIAL 12 WEEKS OF MDR-TB TREATMENT
REFNo: HS471ES

1. To examine the correlations of FDA smear microscopy, PMA-Xpert Ct value &16s rRNA (MBLA) with MGIT-TTP as a reference standard.
2. To evaluate the ability of FDA smear microscopy, PMA-Xpert Ct value, MBLA in predicting 12-weeks MGIT culture conversion (outcome).
3. To evaluate the influence of patient clinical characteristics, baseline resistance profiles, adherence and HIV-status to the performance of the alternative measures of response.

Uganda 2019-12-04 2022-12-04 Medical and Health Sciences Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Evaluation of a new stool-based qPCR for TB diagnosis in children and people living with HIV: a multicentre study in Eswatini, Mozambique and Uganda
REFNo: HS1615ES

To create a biorepository of well characterized pediatric samples at each of the study sites to support the future development and evaluation of novel biomarker research. ,To evaluate the quantitative stool qPCR platform as a tool to monitor treatment response in children and PLHIV,To compare the diagnostic performance of the stool qPCR platform to individual sputum and stool Xpert Ultra, urine LAM, sputum smear, sputum (MGIT) culture results against a clinical diagnosis and bacteriological reference standard,To evaluate the diagnostic accuracy of the stool Mtb qPCR tool compared to a composite reference standard (sputum and stool Xpert Ultra, sputum culture and urine TB-LAM) and clinical diagnosis. ,
Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Feasibility, Usability and Acceptability of stool-based qPCR to diagnose TB in children aged up to 8-years and HIV- positive adults in Mozambique, Eswatini and Uganda: a qualitative study
REFNo: SS1492ES

To identify cultural, socioeconomic and health system barriers and facilitators to the diagnostic tool’s implementation and uptake,To assess healthcare professionals’ perception of usefulness and applicability and related factors,To assess patients’ compliance and satisfaction with the intervention,To assess the participants’ (caretakers and PLWHA)/health professionals’ interpretation of a procedure involving stool collection for TB diagnosis in the light of current information, education communication messages regarding TB transmission,To describe participants’ views on, experiences with, and reactions towards the intervention,To explore participant’s perceptions and attitudes regarding TB in general and diagnosis in particular,To assess the feasibility of stool-based TB diagnostics from the healthcare professionals, patients and caregiver’s perspective in Uganda, Eswatini and Mozambique,
Uganda 2022-10-27 7:29:40 2025-10-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Proof-of- concept: Understanding Non-Tuberculous Mycobacteria Diversity, Evolution, Epidemiology and Pathogenicity in Tuberculosis-High Burden African Contexts (DEEP-NTM): Uganda
REFNo: HS5734ES

Objective 1 (O1) To describe the species and intra-species level diversity of NTM within each geographical area through phylogenomic studies.
Objective 2 (O2) To understand the phylogeography of non-tuberculous mycobacteria in sUganda.
Objective 3 (O3) To assess the significance of NTM isolates and their relation to NTM-PD in different populations.
Objective 4 (O4) To use results as a proof-of-concept to design a prospective multi-centre study to:
i) investigate sub-regional geographical variations
ii) to distinguish variants associated with colonisation and NTM-PD
iii) to identify risk factors, potential routes of acquisition and transmission and clinical outcomes of NTM-PD.
Uganda 2025-04-11 16:38:31 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Performance evaluation of the Truenat® MPX Tests to detect Mpox in Uganda
REFNo: HS5956ES

1) To compare the sensitivity and specificity of the Truenat® MPX assay with BioPerfectus Monkeypox Virus Real Time PCR Kit / Altona Fexstar in detecting Mpox cases in Uganda.
2) To assess the overall diagnostic accuracy, including the rate of false positives and negatives, of the Truenat® MPX assay compared to the RT-PCR standard.
Uganda 2025-06-10 14:33:48 2028-06-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
william Onyayi WHO
ID:
Drivers of Post Voluntary Medical Male Circumcision Best Practices Among Male Circumcised Adolescents 10 - 19 Years in Gulu District
REFNo: HS3127ES

4)To explore the socio-cultural factors influencing post medical male circumcision practices among male circumcised adolescents aged 10-19years in Gulu district,3) To find out the institutional factors influencing post medical male circumcision practices among male circumcised adolescents aged 10-19years in Gulu district,To assess the compliance, personal, institutional and socio-cultural factors influencing post voluntary medical male circumcision practices among male circumcised adolescents 10- 19 years in Gulu district, northern Uganda.,2) To find out the individual factors influencing post medical male circumcision practices among male circumcised adolescents aged 10-19 years in Gulu district,1) To determine the proportion of male adolescents who complied with post medical male circumcision practices among circumcised adolescents aged 10- 19 years in Gulu district,
Uganda 2023-10-23 13:04:11 2026-10-23 Medical and Health Sciences Non-Clinical Trial Degree Award
William  Veness Andrew
ID:
Assessing Causal Processes of Multi-Hazard Risk in the Rwenzori Region
REFNo: NS842ES

Generation of an evidence base for solutions through a multi-hazard risk assessment inthe Rwenzori Mountains
Hydrological characterisation of the highlands
Evidencing the mechanisms of landslides and potential for vegetative stabilisation
Evidencing geomorphological changes in river valleys
Assessment of whether water quality is being impacted by soil erosion
UK 2024-07-26 15:42:01 2027-07-26 Natural Sciences Non-Clinical Trial Degree Award
Willbroad Byamukama
ID: UNCST-2022-R010646
Adoption of Information Communication Technologies in Dissemination of Agricultural Information in Uganda. A case study of Rubanda, Mayuge Districts and Mbarara City
REFNo: A218ES

To establish ICT devices (Radio, mobile phones, television and computers) used by smallholder farmers in Rubanda, Mayuge Districts, and Mbarara City,To establish the extent of ICT usage for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City,To develop and validate a model for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City. ,To examine the factors influencing the adoption of ICT for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City.,To develop an Information Communication Technologies (ICT) model for agricultural information dissemination among smallholder farmers in Rubanda, Mayuge Districts, and Mbarara City. ,
Uganda 2022-09-12 18:31:03 2025-09-12 Agricultural Sciences Non-Clinical Trial Degree Award
Willbroad Byamukama
ID: UNCST-2022-R010646
RURAL LANDLESSNESS AND FOOD INSECURITY IN UGANDA; A CASE OF KIGEZI SUB-REGION (KABALE, RUBANDA, RUKIGA, AND KISORO DISTRICTS)
REFNo: A561ES

iii. To establish workable strategies to address food insecurity in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,ii. To examine the effect of rural landlessness on food insecurity in Kigezi region (Kabale, Rubanda, Rukiga, and Kisoro).,i. To examine the causes of rural landlessness in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,The purpose of the study is to examine the effect of rural landlessness and food insecurity in, Uganda case of Kigezi region and come up with strategies to increase food security in Kigezi sub region with the rural landlessness.,
Uganda 2025-04-09 16:09:36 2028-04-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
Exploring the mental health needs of orphans and vulnerable children in Nakivale Refugee Settlement, Uganda
REFNo: SS2264ES

• To understand the experiences, needs and views on mental health issues of OVCs and their carers
• To explore factors related to their participation in research

Uganda 2024-01-31 11:19:28 2027-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
Effectiveness of Cognitive behaviour therapy for mental health problems among adult patients with type-II diabetes mellitus: a controlled study
REFNo: SS3413ES

a. To assess the effectiveness of CBT in treating mental health problems (psychological distress, depression, anxiety, quality of life, treatment adherence, hopelessness, pessimism) among adult patients with T2DM
b. To assess whether CBT affords a better control of glycaemia and the metabolic disturbances associated with T2DM.

Uganda 2025-01-31 7:37:29 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wietse Tol
ID: UNCST-2021-R013085
AlCohol use in HumanitariAN settings: a programme of work to address alcohol use disorders and associated adversities among conflict-affected populations in UGanda and UkrainE (CHANGE)
REFNo: SS1596ES

• To identify strategies and techniques from evidence-based alcohol use therapies which can be integrated into PM+, and to develop a new intervention called PM+A (Problem Management Plus Alcohol)
• To adapt PM+A to local circumstances, and to examine the feasibility, acceptability, perceived effectiveness, and preliminary impact of PM+A
• To evaluate effectiveness and cost-effectiveness of PM+A through two single-blind randomised controlled trials in Uganda and Ukraine
• To explore the process of implementation, and to identify, characterise and explain mechanisms that promote or inhibit the delivery and take-up of PM+A in both settings
• To examine the potential for scaling-up PM+A in Uganda and Ukraine

Netherlands 2023-02-17 12:18:30 2026-02-17 Social Science and Humanities Clinical Trial Non-degree Award
Wietse Tol
ID: UNCST-2021-R013085
CHANGE: AlCohol use in HumanitariAN settings: a programme of work to address alcohol use disorders and associated adversities among conflict-affected populations in UGanda (CHANGE)
REFNo: SS1676ES

Aim: to evaluate effectiveness and cost-effectiveness of the CHANGE intervention for male South Sudanese refugees in resettlement areas in northern Uganda.

• Objective 1: evaluate effectiveness and cost-effectiveness of the CHANGE intervention at reducing percentage of days drinking at 3 and 12 months (CHANGE intervention and EUC vs. EUC alone)
• Objective 2: explore implementation processes and identify mechanisms that promote or inhibit the uptake of the CHANGE intervention amongst providers and participants


Netherlands 2023-12-01 16:59:10 2026-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wilfred Eneku
ID:
Molecular and Sero-epidemiology of zoonotic rickettsia in five districts of Uganda
REFNo: HS897ES

1. To determine seroprevalence and risk factors to rickettsioses in the five districts from archived serum samples and the accompanying secondary data
2. To characterize rickettsia in Vectors in five districts of Uganda
3. To assess the relative densities of ticks and fleas on animals and environment in the five districts of Uganda

Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Degree Award
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