Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Wycliff Odude
ID: UNCST-2024-R002431
 Small-scale field evaluation of the efficacy, residual activity and acceptability of Sovrenta® 15WP against Malaria Vectors in Adjumani district, West Nile, Uganda.
REFNo: HS5300ES

1. To determine the susceptibility levels of both wild-type and Kisumu strain malaria vectors to Sovrenta® 15WP insecticide in Adjumani District, West Nile, Uganda.
2. To determine the comparative residual activity of Sovrenta® 15WP and Actellic 300CS insecticides on common wall-type surfaces in Adjumani, West Nile, Uganda over 10 months.
3. To generate specific information related to the acceptability of Sovrenta® 15WP insecticide as a new product by the community in Adjumani, West Nile, Uganda.
4. To assess the ease of use of the Sovrenta by the spray operators under field conditions in Adjumani District, West Nile, Uganda.

Uganda 2024-12-10 16:05:33 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AMPAIRE WYCLIFFE
ID: UNCST-2025-R017187
 SOURCE APPORTIONMENT AND BIODEGRADATION OF PAHs AND PFAS FROM WATER AND SEDIMENTS ALONG L. ALBERT
REFNo: NS1070ES

i. To determine the concentrations of 25 selected PAHs and 18 PFAS in water and sediment samples from Lake Albert using GC-MS/MS and LC-MS/MS, respectively.
ii. To identify the potential sources and spatial distribution patterns of PAHs and PFAS in Lake Albert using principal component analysis (PCA), HCA multivariate statistical techniques, and a fugacity-based model.
iii. To evaluate the human and ecological health risks posed by combined PAH and PFAS contamination in Lake Albert, using the US EPA Exposure Factors Handbook for risk characterization.
iv. To come up with potential biodegradation pathways for one selected PAH and one selected PFAS compound identified in water and sediment samples.

 Uganda 2025-12-05 19:12:24 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
WYCLIFF TUSIIME EDWIN
ID:
Teachers digital competence in the Teaching of Art and Design in Teacher Training Institutions in Uganda
REFNo: SS152ES

(i) to analyze if and how teachers use digital tools in the teaching of art and design?; (ii) to examine the challenges and /or opportunities teachers meet in the use of digital tools during teaching processes in Art and Design; (iii) to establish ways teachers can develop digital competence to enrich the teaching of art and design in TTIs?
 Uganda 2018-06-13 2021-06-13 Social Science and Humanities Degree Award
Wyatt Brooks James
ID:
Community Lending and Outside Capital (CLOC)
REFNo: SS339ES

To measure the impact of community lending and outside capital on SILC members’ returns and default rate behavior, levels of liquid savings, and change in livelihood.
USA 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
wasswa william
ID: UNCST-2019-R001217
 Automated Diagnosis and Classification of Cervical Cancer from Pap-Smear Images.
REFNo: HS129ES

The general objective of this research is to design and validate a robust automated tool for diagnosis and classification of cervical cancer using hybrid Segmentation and Classification techniques applied to Pap smear images. To achieve this objective and address the research problem, the following specific research objectives have been formulated. 1. To review state of art prominent recent publications focusing on the application of machine learning and medical imaging in automated detection and classification of Cervical Cancer from Pap-smear images. 2. To acquire Pap-smear images and develop a hybrid technique for automated segmentation and classification of cervical cancer. 3. To develop an interactive graphical user interface (GUI) platform to facilitate the automated diagnosis and classification of cervical cancer from Pap-smear images. 4. To test and validate the developed platform using patient results obtained from a manual screening of the Pap-smear images by a trained and experienced cytologist and also comparing the algorithms with results obtained by other researchers on the same open source datasets (Hervlet Cervical cancer dataset).
Uganda 2018-05-22 2021-05-22 Medical and Health Sciences Degree Award
Kirsten Ward
ID:
Evaluation of delivery practices for multiple vaccines at a single immunization visit in low- and middle-income countries Uganda
REFNo: HS170ES

Aim: This evaluation aims to describe current preparation, administration and communication practices in the delivery of more than one vaccine to a single child at a single immunization visit in Uganda. Objectives: 1. To document the processes and techniques used to prepare and administer more than one vaccine, primarily injectable vaccines, to children in Uganda; 2. To understand the timing, content, and extent of communication messages about co-administration of one or more vaccines and post-vaccination care delivered by providers to caregivers in Uganda; and 3. To use results from 1 & 2 to develop recommendations about best practices for: a) the preparation and delivery of multiple vaccines with a focus on injectable vaccines, and b) provider communication to the caregiver about delivery of multiple vaccines and post-vaccination care.
 Australia 2018-05-15 2021-05-15 Medical and Health Sciences Non-degree Award
wilberforce Turyahikayo
ID:
Antecedents of Organisational Effectiveness of Public Universities in Uganda
REFNo: SS1694ES

To assess whether leadership styles are antecedents of organisational effectiveness of public universities in Uganda.

To examine whether organisational culture is an antecedent of organisational effectiveness of public universities in Uganda.

To examine whether leadership styles are antcendents organisational communication in public Universities.

To analyse whether organisational communication is an antecedent of organisational effectiveness in public universities in Uganda.

To examine the moderating effect of organisational culture on the relatiohship between leadership styles and organisational effectiveness of public universities in Uganda.

To assess the mediating effect of organisational communication on the relationship between leadership styles and organisational effectiveness of public universities in Uganda.

 Uganda 2023-07-03 13:36:57 2026-07-03 Social Science and Humanities Non-Clinical Trial Degree Award
Warren Phipps
ID:
Attitudes and Practices of Antimicrobial Resistance and Stewardship at the Uganda Cancer Institute
REFNo: HS871ES

We will investigate the knowledge, attitudes, and practices about antimicrobial use and antimicrobial resistance among the doctors (including medical officers, fellows, oncologists, and surgeons), nurses, and pharmacists at the Uganda Cancer Institute (UCI).

The aims of the study are;
Aim 1: To examine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial resistance.
Aim 2: To determine the current knowledge and attitudes of UCI healthcare providers towards antimicrobial stewardship.
Aim 3: To understand perceived barriers to the diagnosis and management of infections in patients at UCI

USA 2021-01-22 2024-01-22 Medical and Health Sciences Non-degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
 Field clinical evaluation of the NG-Test Point of Care lateral flow device (LFD) for monkeypox diagnosis in Uganda
REFNo: HS5602ES

To evaluate detection performance and clinical agreement of Rapid Point of Care (POC) antigen assay for diagnosis of mpox among clinically suspected patients in healthcare facilities in Kampala, Wakiso, Mukono, and Nakasongola districts in Uganda.

Specific objective 1
To determine the diagnostic sensitivity, specificity, & predictive values of the Rapid NG-Test antigen
assay in comparison to PCR and sequencing among patients with mpox
Specific objective 2
To identify MPXV clade (s) circulating among patients with mpox through virologic metagenomic
sequencing

 Uganda 2025-03-14 17:48:15 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
 UNDERSTANDING INFECTIOUS AND NON-INFECTIOUS DISEASE TRENDS IN KANUNGU DISTRICT TO INFORM PUBLIC HEALTH PLANNING AND INTERVENTIONS
REFNo: HS6462ES

1. Determine types and trends of diseases in Kanungu from 2015–2025.
2. Compare quality and quantity of HCF records with MoH’s DHSI data.

 Uganda 2025-10-24 17:28:54 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Management of Lower Respiratory Tract Infections in Sub-Saharan Africa, a Pragmatic Approach
REFNo: HS1160ES

Primary objective: To define aetiology and resistance patterns of clinically diagnosed CAP among hospitalized individuals using a comprehensive microbiological approach.

Secondary objectives:
1.To determine the level of agreement between molecular and conventional laboratory testing for the diagnosis of CAP.
2.To determine clinical predictors of treatment outcomes (early treatment failure, mortality) in patients hospitalized with CAP.
3.To determine the role of the CURB-65 severity score and biomarkers (CRP and PCT) in predicting treatment outcomes (early treatment failure, mortality) of patients hospitalized with CAP in a high HIV burden setting.

 Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 The effect of household air pollution on lung function recovery in COVID-19 disease
REFNo: SS892ES

Main objective
- The overall aim of the study is to measure the effect of air pollution on lung function recovery after COVID-19 pneumonia.

-Measure the effect of air pollution exposure on lung function recovery after COVID-19.

Specific Objectives

- Measure the effect of mobility on air pollution exposure and lung function recovery after COVID-19.
-
 Uganda 2021-06-16 2024-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) Study
REFNo: HS1482ES

1. To evaluate early and late prototypes of novel TB diagnostics to provide feedback to developers on performance and usability, inform further development and identify potential strategies for use in endemic settings.
2. To conduct large-scale, multi-center assessments of the accuracy and usability of design-locked novel TB diagnostics, including in special populations, to facilitate World Health Organization (WHO) policy review.
3. To assess the potential costs and epidemiological impact of novel TB diagnostics alone or in combination with current tests and algorithms to inform their further assessment and/or the WHO policy review process.
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Candidate Clinical Correlate as Prognostic Outcome for TB (C3PO) Study
REFNo: HS6545ES

Our specific aims are: 1. To evaluate end-of-treatment (EOT) biomarkers as predictors of recurrent TB 2. To evaluate novel cough and activity biomarkers as predictors of post-TB lung health
 Uganda 2025-11-21 13:53:39 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Irene  Wobusobozi
ID:
UTILIZATION OF LABORATORY TESTS TO GUIDE ANTIBIOTIC PRESCRIPTION: A CASE STUDY OF MUKONO GENERAL HOSPITAL
REFNo: HS4785ES

1. To determine the proportion of patients for whom biomarker tests were done. 2. To determine the proportion of patients with antibiotic prescriptions based on biomarker test results 3. To assess the turnaround time for the processing and referring microbial samples 4. To explore the barriers and facilitators of using laboratory tests to guide antibiotic prescription in Mukono Hospital. ,
 Uganda 2024-10-08 17:36:15 2027-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WINNIE NAMBATYA
ID:
Risk factors for Neural Tube Defects among children attending Mulago and Kawempe Hospitals: A case control study
REFNo: HS430ES

1. To determine the types of NTDs in Mulago National Referral Hosptial among infants,
2. To determine the factors associate with the NTDs,
3. To compare the factors with the type of NTD

 Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Non-degree Award
WINNIE NAMBATYA
ID:
Evaluation of the complexity of medicine regimens and drug therapy problems among children with sickle cell anemia in Jinja Regional Referral Hospital: A prescription audit
REFNo: HS1299ES

• To determine the complexity of medication regimens prescribed to the patients with SCA.
• To determine the incidence of DTPs among medications prescribed to children with SCA.

 Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnifred Namazzi Birabwa
ID: UNCST-2025-R017998
 AN ASSESSMENT FOR THE APPROPRIATE CULTURALLY RESPONSIVE PEDAGOGY IN IMPLEMENTING THE COMPETENCY BASED CURRICULUM AMONG INDIGENOUS BATWA COMMUNITIES IN UGANDA
REFNo: SS4097ES

1. What Batwa culturally responsive learning experiences can teachers integrate in teaching to effectively implement the CBC in Batwa heterogeneous classrooms? 2. How can the teachers utilize Batwa learners’ cultural backgrounds to address their learning needs when implementing the CBC in Batwa heterogeneous classrooms? 3. How can teachers integrate culturally responsive teaching methods to enable effective implementation of the CBC in Batwa heterogeneous classrooms? 4. What are the challenges of integrating CRP into the implementation of the competency based curriculum in Batwa heterogeneous classrooms?
 Uganda 2025-09-12 16:53:22 2028-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
 Tuberculosis, Alcohol, and Lung Comorbidities (TALC) Study
REFNo: HS2705ES

Qualitatively evaluate factors for tailoring pharmaco-behavioral alcohol and smoking interventions in PLWH being treated for TB. ,Explore how smoking alters the association of past-month heavy drinking and post-TB lung disease progression over time,• Aim 1b. Assess the association of past-month heavy drinking and post-TB lung disease progression over time. This aim uses recent alcohol use (30-day Timeline Followback, PEth) since direct mechanisms (e.g., alcohol toxicity) may drive the physiologic, anatomic, and immunologic outcomes of interest. We define past-month heavy drinking as ≥7 drinks/week (women), ≥14 drinks/week (men) or PEth>200 ng/mL.,• Aim 1a. Determine if past-year hazardous drinking is associated with post-TB lung disease. ,Aim 1. Determine the relationship between hazardous drinking and post-TB lung disease in PLWH.,
 Uganda 2023-03-24 2:08:05 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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